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. 1968 Jan;59(1):139–144. doi: 10.1073/pnas.59.1.139

The immediate precursor of viral RNA in the Q-beta-repicase reaction.

N R Pace, D H Bishop, S Spiegelman
PMCID: PMC286013  PMID: 5242117

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Billeter M. A., Libonati M., Viñuela E., Weissmann C. Replication of viral ribonucleic acid. X. Turnover of virus-specific double-stranded ribonucleic acid during replication of phage MS2 in Escherichia coli. J Biol Chem. 1966 Oct 25;241(20):4750–4757. [PubMed] [Google Scholar]
  2. Bishop D. H., Claybrook J. R., Pace N. R., Spiegelman S. An analysis by gel electrophoresis of Q-beta-RNA complexes formed during the latent period of an in vitro synthesis. Proc Natl Acad Sci U S A. 1967 May;57(5):1474–1481. doi: 10.1073/pnas.57.5.1474. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Bishop D. H., Claybrook J. R., Spiegelman S. Electrophoretic separation of viral nucleic acids on polyacrylamide gels. J Mol Biol. 1967 Jun 28;26(3):373–387. doi: 10.1016/0022-2836(67)90310-5. [DOI] [PubMed] [Google Scholar]
  4. Bishop D. H., Pace N. R., Spiegelman S. The mechanism of replication: a novel polarity reversal in the in vitro synthesis of Q-beta-RNA and its complement. Proc Natl Acad Sci U S A. 1967 Oct;58(4):1790–1797. doi: 10.1073/pnas.58.4.1790. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. ERIKSON R. L., FENWICK M. L., FRANKLIN R. M. REPLICATION OF BACTERIOPHAGE RNA: STUDIES ON THE FATE OF PARENTAL RNA. J Mol Biol. 1964 Dec;10:519–529. doi: 10.1016/s0022-2836(64)80070-x. [DOI] [PubMed] [Google Scholar]
  6. FENWICK M. L., ERIKSON R. L., FRANKLIN R. M. REPLICATION OF THE RNA OF BACTERIOPHAGE R17. Science. 1964 Oct 23;146(3643):527–530. doi: 10.1126/science.146.3643.527. [DOI] [PubMed] [Google Scholar]
  7. Francke B., Hofschneider P. H. Uber infektiöse Substrukturen aus Escherichia coli Bakteriophagen. VII. Formation of a biologically intact replicative form in ribonucleic acid bacteriophage (M12)-infected cells. J Mol Biol. 1966 Apr;16(2):544–552. doi: 10.1016/s0022-2836(66)80190-0. [DOI] [PubMed] [Google Scholar]
  8. Franklin R. M. Purification and properties of the replicative intermediate of the RNA bacteriophage R17. Proc Natl Acad Sci U S A. 1966 Jun;55(6):1504–1511. doi: 10.1073/pnas.55.6.1504. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. HARUNA I., NOZU K., OHTAKA Y., SPIEGELMAN S. AN RNA "REPLICASE" INDUCED BY AND SELECTIVE FOR A VIRAL RNA: ISOLATION AND PROPERTIES. Proc Natl Acad Sci U S A. 1963 Nov;50:905–911. doi: 10.1073/pnas.50.5.905. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Haruna I., Spiegelman S. Specific template requirments of RNA replicases. Proc Natl Acad Sci U S A. 1965 Aug;54(2):579–587. doi: 10.1073/pnas.54.2.579. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Loening U. E. The fractionation of high-molecular-weight ribonucleic acid by polyacrylamide-gel electrophoresis. Biochem J. 1967 Jan;102(1):251–257. doi: 10.1042/bj1020251. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Mills D. R., Pace N. R., Spiegelman S. The in vitro synthesis of a noninfectious complex containing biologically active viral RNA. Proc Natl Acad Sci U S A. 1966 Dec;56(6):1778–1785. doi: 10.1073/pnas.56.6.1778. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Pace N. R., Bishop D. H., Spiegelman S. Examination of the Qbeta-replicase reaction by sucrose gradient and gel electrophoresis. J Virol. 1967 Aug;1(4):771–778. doi: 10.1128/jvi.1.4.771-778.1967. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Pace N. R., Bishop D. H., Spiegelman S. The kinetics of product appearance and template involvement in the in vitro replication of viral RNA. Proc Natl Acad Sci U S A. 1967 Aug;58(2):711–718. doi: 10.1073/pnas.58.2.711. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Pace N. R., Spiegelman S. In vitro synthesis of an infectious mutant RNA with a normal RNA replicase. Science. 1966 Jul 1;153(3731):64–67. doi: 10.1126/science.153.3731.64. [DOI] [PubMed] [Google Scholar]
  16. Pace N. R., Spiegelman S. The synthesis of infectious RNA with a replicase purified according to its size and density. Proc Natl Acad Sci U S A. 1966 Jun;55(6):1608–1615. doi: 10.1073/pnas.55.6.1608. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Spiegelman S., Haruna I., Holland I. B., Beaudreau G., Mills D. The synthesis of a self-propagating and infectious nucleic acid with a purified enzyme. Proc Natl Acad Sci U S A. 1965 Sep;54(3):919–927. doi: 10.1073/pnas.54.3.919. [DOI] [PMC free article] [PubMed] [Google Scholar]

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