Abstract
Synthetic 2-stranded RNA—a helical complex formed by duplexing homopolymers of polyriboinosinic and polyribocytidylic acids (poly I:C)—induced host resistance to foot-and-mouth disease virus when microgram quantities were injected into mice. There was a graded response as shown by titrations of polynucleotide complex or virus. Protection was effective for >48 hours after a single injection of polynucleotide complex. Survival and serum interferon titers were directly related.
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Selected References
These references are in PubMed. This may not be the complete list of references from this article.
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