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The American Journal of Tropical Medicine and Hygiene logoLink to The American Journal of Tropical Medicine and Hygiene
. 2010 May;82(5):758. doi: 10.4269/ajtmh.2010.09-0628

Unusually Thickened Ulnar Nerve and Lagophthalmos in Leprosy

Ravindra Kumar Garg 1,*
PMCID: PMC2861401  PMID: 20439951

Case summary

Leprosy is a common cause of neuropathy. Thickened peripheral nerves are one of the cardinal features. Ulnar and common peroneal nerves are the most frequent thickened nerves.1 Figure 1 shows a visibly thickened ulnar nerve in a 22-year-old man presenting with mononeuritis multiplex along with hypopigmented and hypoesthetic skin lesions. Borderline leprosy has a high propensity to involve nerve trunks resulting in mononeuritis multiplex. Figure 2 shows lagophthalmos in a 45-year-old patient of lepromatous leprosy. Lagophthalmos is the inability to close the eye because of paralysis of the upper eyelid. Involvement of zygomatic and temporal branches of facial nerve result in lagophthalmos.2

Figure 1.

Figure 1.

Unusually thickened ulnar nerve (fine arrows) in a patient with borderline leprosy. There is a hypopigmented skin lesion on the dorsal aspect of the elbow (a thick arrow). This figure appears in color at www.ajtmh.org.

Figure 2.

Figure 2.

Lagophthalmos in a patient with lepromatous leprosy. Patient is attempting to close his eyelids but he is unable to close them. This figure appears in color at www.ajtmh.org.

Footnotes

Disclosure: The journal has permission from the patient shown in Figure 2 to publish his photograph. Ravindra Kumar Garg reports no financial disclosures.

Author's address: Ravindra Kumar Garg, Department of Neurology, Chhatrapati Shahuji Maharaj Medical University, Uttar Pradesh, Lucknow, India, E-mail: garg50@yahoo.com.

References

  • 1.Saunderson P, Gebre S, Desta K, Byass P, Lockwood DN. The pattern of leprosy-related neuropathy in the AMFES patients in Ethiopia: definitions, incidence, risk factors and outcome. Lepr Rev. 2000;71:285–308. doi: 10.5935/0305-7518.20000033. [DOI] [PubMed] [Google Scholar]
  • 2.Turkof E, Richard B, Assadian O, Khatri B, Knolle E, Lucas S. Leprosy affects facial nerves in a scattered distribution from the main trunk to all peripheral branches and neurolysis improves muscle function of the face. Am J Trop Med Hyg. 2003;68:81–88. [PubMed] [Google Scholar]

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