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Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 1969 Sep;64(1):404–410. doi: 10.1073/pnas.64.1.404

AGING OF α-CRYSTALLINS DURING DEVELOPMENT OF THE LENS*

Winifred G Palmer 1, John Papaconstantinou 1
PMCID: PMC286176  PMID: 4983823

Abstract

Fetal α-crystallin from the bovine lens can be resolved into three major subunit fractions by ion exchange chromatography. A fourth subunit gradually arises during the development of the lens. Incorporation studies indicate that this subunit is not formed by de novo synthesis but by the chemical conversion of one subunit into another. Possible mechanisms for this conversion are discussed.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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