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. 1970 Jan;65(1):110–113. doi: 10.1073/pnas.65.1.110

Induction of Stalk Cell Differentiation by Cyclic AMP in the Cellular Slime Mold Dictyostelium discoideum*

John Tyler Bonner 1
PMCID: PMC286198  PMID: 4313192

Abstract

Cyclic AMP, which is a cell attractant (acrasin) for Dictyostelium discoideum, will cause isolated, unaggregated cells to turn directly into stalk cells containing thick celluloselike walls and large vacuoles. From previous work we know that in the cell mass, acrasin is produced solely in the region of stalk formation during fruiting, that stalk formation involves a high level of catabolism, and that cyclic AMP stimulates catabolic enzymes in other systems. These facts obviously suggest that in the development of D. discoideum, cyclic AMP might be a key factor in stalk cell differentiation.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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