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. Author manuscript; available in PMC: 2011 Jun 1.
Published in final edited form as: Resuscitation. 2010 Mar 17;81(6):749–754. doi: 10.1016/j.resuscitation.2009.12.007

Table 2.

Physiologic Data and Lung Injury and Inflammation at 3 h or prior to Death

Group UVC NTNI NT LT HT
pH --- 7.27±0.05 7.20±0.14 7.22±0.1 6.98±0.22+
PaCO2 (mmHg) --- 58±7 75±34 58±11 113±44+
PIP (cmH2O) --- 26±6.9 34±7.5 28±5.8 38±3.2+
VT/kg (mL/kg) --- 7.2±1.6 7.8±1.9 6.0±1.4 7.1±1.8
Pulse Rate (bpm) --- 167±15 174±29 118±21+ 209±44+
Lung Injury and Inflammatory Responses
Pneumothorax N --- 0 2 0 6
Death < 3 h N --- 0 0 0 5
PIE at autopsy N 0 1 5 2 7
ALI score (0-6) 0.6±0.4 1.6±1.3 4.2±0.3*+ 1.4±0.9 3.2±0.7*
Inflammatory Cells in BAL ×105/kg 1.9±4 147±130* 247±157* 115±46* 146±60*
Protein in BAL mg/kg 25±12 60±31* 107±24*+ 94±21*+ 86±20*

UVC= unventilated control group, NTNI= normothermic positive control group, NT= normothermic injury group, LT= hypothermic injury group, HT= hyperthermic injury group. bpm= beats per minute, PIE= pulmonary interstitial emphysema, ALI= acute lung injury, BAL= bronchoalveolar lavage fluid. (N) represents the number of affected animals per group. Data presented as mean ± SD.

*

p < 0.05 vs. UVC

+

p < 0.05 vs. NTNI.