Table 3. Overall five-year survival (OS) rates after relapse, by site and time to relapse.
5-year Survival Post Relapse | Relapse Site | ||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Isolated Marrow Relapse | Concurrent Marrow Relapse | Isolated CNS Relapse | Isolated Testicular Relapse | Other extramedullary +/-CNS Relapse | |||||||||||
Time to relapse | n | Survival (%) | SE | n | Survival (%) | SE | n | Survival (%) | SE | n | Survival (%) | SE | n | Survival (%) | SE |
Early1 | 412 | 11.49 | 1.91 | 86 | 11.64 | 4.89 | 175 | 43.51 | 4.45 | 15 | 13.64 | 16.56 | 23 | 10.38 | 11.32 |
Intermediate1 | 324 | 18.42 | 3.09 | 54 | 39.79 | 9.31 | 180 | 67.99 | 4.53 | 35 | 52.20 | 11.41 | 17 | 50.47 | 25.12 |
Late1 | 387 | 43.46 | 5.23 | 124 | 60.34 | 8.29 | 54 | 78.25 | 8.85 | 54 | 59.96 | 15.49 | 21 | 85.15 | 14.67 |
Overall2 | 1123 | 24.1 | 2.1 | 264 | 39.4 | 5.0 | 409 | 58.7 | 3.2 | 104 | 58.0 | 8.2 | 61 | 55.9 | 9.9 |
p-value < 0.0001 compares survival rates by sites of relapse within each time period.
“Overall survival” refers to an unadjusted comparison of sites of relapse.