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. Author manuscript; available in PMC: 2011 May 11.
Published in final edited form as: Biochemistry. 2010 May 11;49(18):3824–3841. doi: 10.1021/bi100055m

FIGURE 5. Conformational changes in CheA:CheW on binding Tm14.

FIGURE 5

Comparison of initial structure of CheAΔ289/CheW (grey) to the final structure (yellow) in the presence of Tm14 after rigid body refinement against PDS distance restraints of Table 1. P4 domains are omitted from the left and center structures for clarity. Regions of CheW important for binding MCPs are in red. Right - A dimeric MCP (brown) is docked in the pocket created by the rotation of CheW.