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. 1976;3(4):394–407.

QUANTITATIVE ASSESSMENT OF LEFT VENTRICULAR ASYNERGY

Pedro R Hernandez-Lattuf 1, Efrain Garcia 1, Jose Suarez De Lezo 1,*, William R C Murphy 1,**, Robert J Hall 1
PMCID: PMC287623  PMID: 15216142

Abstract

Myocardial performance in the intact human heart can be assessed from the analysis of ejection phase indices. Accordingly, among 20 consecutive patients who were studied by means of biplane left ventricular cineangio-cardiography, 18 were selected solely on the basis of high quality angiograms. The characteristics of left ventricular contraction were expressed quantitatively by the systolic ejection fraction, the mean velocity of circumferential fiber shortening at the left ventriculalr equator, and at several chords, the mean velocity of shortening of the hemichords and the mean normalized systolic ejection rate. All 18 patients had abnormalities of contraction based on the velocity of the hemichords. Both ejection fraction and mean normalized systolic ejection rate showed a low sensitivity in detecting depressed myocardial function in patients with segmental asynergy. Equatorial VCF provided additional information only when the affected areas were adjacent to the left ventricular minor axis. The sensitivity of this index was markedly increased by construction of several chords perpendicular to the left ventricular long axis (segmental VCF). However, when only one wall was affected, measurement of the velocity of shortening of the hemichords provided a better definition of the regional performance.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Burggraf G. W., Craige E. Echocardiographic studies of left ventricular wall motion and dimensions after valvular heart surgery. Am J Cardiol. 1975 Apr;35(4):473–480. doi: 10.1016/0002-9149(75)90829-2. [DOI] [PubMed] [Google Scholar]
  2. Chatterjee K., Sacoor M., Sutton G. C., Miller G. A. Assessment of left ventricular function by single plane cineangiographic volume analysis. Br Heart J. 1971 Jul;33(4):565–571. doi: 10.1136/hrt.33.4.565. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Dodge H. T., Sandler H., Baxley W. A., Hawley R. R. Usefulness and limitations of radiographic methods for determining left ventricular volume. Am J Cardiol. 1966 Jul;18(1):10–24. doi: 10.1016/0002-9149(66)90191-3. [DOI] [PubMed] [Google Scholar]
  4. Gaasch W. H., Battle W. E., Oboler A. A., Banas J. S., Jr, Levine H. J. Left ventricular stress and compliance in man. With special reference to normalized ventricular function curves. Circulation. 1972 Apr;45(4):746–762. doi: 10.1161/01.cir.45.4.746. [DOI] [PubMed] [Google Scholar]
  5. Herman M. V., Gorlin R. Implications of left ventricular asynergy. Am J Cardiol. 1969 Apr;23(4):538–547. doi: 10.1016/0002-9149(69)90007-1. [DOI] [PubMed] [Google Scholar]
  6. Herman M. V., Heinle R. A., Klein M. D., Gorlin R. Localized disorders in myocardial contraction. Asynergy and its role in congestive heart failure. N Engl J Med. 1967 Aug 3;277(5):222–232. doi: 10.1056/NEJM196708032770502. [DOI] [PubMed] [Google Scholar]
  7. Hernandez-Lattuf P. R., Quinones M. A., Gaasch W. H. Usefulness and limitations of circumferential fibre shortening velocity in evaluating segmental disorders of left ventricular contraction. Br Heart J. 1974 Dec;36(12):1167–1174. doi: 10.1136/hrt.36.12.1167. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Hood W. B., Jr Experimental myocardial infarction. 3. Recovery of left ventricular function in the healing phase. Contribution of increased fiber shortening in noninfarcted myocardium. Am Heart J. 1970 Apr;79(4):531–538. doi: 10.1016/0002-8703(70)90259-0. [DOI] [PubMed] [Google Scholar]
  9. Karliner J. S., Gault J. H., Eckberg D., Mullins C. B., Ross J., Jr Mean velocity of fiber shortening. A simplified measure of left ventricular myocardial contractility. Circulation. 1971 Sep;44(3):323–333. doi: 10.1161/01.cir.44.3.323. [DOI] [PubMed] [Google Scholar]
  10. Krayenbuehl H. P., Rutishauser W., Wirz P., Amende I., Mehmel H. High-fidelity left ventricular pressure measurements for the assessment of cardiac contractility in man. Am J Cardiol. 1973 Apr;31(4):415–427. doi: 10.1016/0002-9149(73)90289-0. [DOI] [PubMed] [Google Scholar]
  11. Liedtke A. J., Gault J. H., Leaman D. M., Blumenthal M. S. Geometry of left ventricular contraction in the systolic click syndrome. Characterization of a segmental myocardial abnormality. Circulation. 1973 Jan;47(1):27–35. doi: 10.1161/01.cir.47.1.27. [DOI] [PubMed] [Google Scholar]
  12. Mirsky I., Pasternac A., Ellison R. C. General index for the assessment of cardiac function. Am J Cardiol. 1972 Oct;30(5):483–491. doi: 10.1016/0002-9149(72)90038-0. [DOI] [PubMed] [Google Scholar]
  13. Noble M. I. Problems concerning the application of concepts of muscle mechanics to the determination of the contractile state of the heart. Circulation. 1972 Feb;45(2):252–255. doi: 10.1161/01.cir.45.2.252. [DOI] [PubMed] [Google Scholar]
  14. Peterson K. L., Skloven D., Ludbrook P., Uther J. B., Ross J., Jr Comparison of isovolumic and ejection phase indices of myocardial performance in man. Circulation. 1974 Jun;49(6):1088–1101. doi: 10.1161/01.cir.49.6.1088. [DOI] [PubMed] [Google Scholar]
  15. Peterson K. L., Uther J. B., Shabeetai R., Braunwald E. Assessment of left ventricular performance in man. Instantaneous tension-velocity-length relations obtained with the aid of an electromagnetic velocity catheter in the ascending aorta. Circulation. 1973 May;47(5):924–935. doi: 10.1161/01.cir.47.5.924. [DOI] [PubMed] [Google Scholar]
  16. Ross J., Jr, Peterson K. L. On the assessment of cardiac inotropic state. Circulation. 1973 Mar;47(3):435–438. doi: 10.1161/01.cir.47.3.435. [DOI] [PubMed] [Google Scholar]
  17. SANDLER H., DODGE H. T. LEFT VENTRICULAR TENSION AND STRESS IN MAN. Circ Res. 1963 Aug;13:91–104. doi: 10.1161/01.res.13.2.91. [DOI] [PubMed] [Google Scholar]

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