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. 1979 Sep;6(3):271–282.

SEQUENTIAL HEMODYNAMIC STUDIES OF THE IONESCU-SHILEY PERICARDIAL XENOGRAFT VALVE UP TO SIX YEARS AFTER IMPLANTATION

Anand P Tandon 1, Donald R Smith 1, Marian I Ionescu 1
PMCID: PMC287795  PMID: 15216303

Abstract

Sequential hemodynamic studies consisting of one preoperative and three postoperative cardiac catheterizations were undertaken in 19 patients at approximately 1, 4, and 6 years after valve replacement. Thirteen patients had aortic and six patients had mitral pericardial xenograft valves. Significant improvement was noted in various hemodynamic parameters in both groups of patients at the postoperative studies as compared to the preoperative findings. In patients with aortic valve replacement, the peak systolic gradient was 7.0 ± 1.2 mm Hg at rest, and 10.0 ± 1.6 mm Hg after exercise during the third postoperative study. The calculated xenograft orifice areas were 1.6 ± 0.1 cm2 at rest and 2.1 ± 0.2 cm2 after exercise in the aortic group, and 2.2 ± 0.2 cm2 at rest and 2.7 ± 0.2 cm2 after exercise in the mitral group at the third postoperative investigation. No significant change was noted among the three postoperative studies in the hemodynamic parameters. The results confirm the maintenance of functional performance of the Ionescu-Shiley pericardial xenograft up to 73 months after valve replacement.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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