Following the publication of our article [1] we noticed an error in Table 1 relating to the number of patients who received adjuvant therapy. The correct table is given here (Table 1).
Table 1.
Patient characteristics for model development (ECRIC) and validation (WMCIU) cohorts
| ECRIC | WMCIU | |||
|---|---|---|---|---|
| Total Number of Subjects | 5,694 | 5,468 | ||
| Total time at risk (years) | 31,904 | 25,917 | ||
| Median follow-up (years)* | 5.65 | (0.04-8.00)† | 4.85 | (0.07-8.00)† |
| Number of breast cancer deaths | 737 | 668 | ||
| Number of other deaths | 338 | 287 | ||
| Annual breast cancer mortality rate | 0.023 | (0.021-0.025)‡ | 0.026 | (0.024-0.028)‡ |
| 5-year breast cancer survival rate | 0.89 | (0.88-0.90)‡ | 0.88 | (0.87-0.89)‡ |
| Median age at diagnosis, years | 58 | (23-95)† | 58 | (22-93)† |
| Number | % | Number | % | |
| Age, years | ||||
| <35 | 111 | 2 | 108 | 2 |
| 35-49 | 1,172 | 21 | 1,195 | 22 |
| 50-64 | 2,630 | 46 | 2,393 | 44 |
| 65-74 | 1,124 | 20 | 1,101 | 20 |
| 75+ | 657 | 12 | 671 | 12 |
| Nodal status | ||||
| 0 | 3,532 | 62 | 3,184 | 58 |
| 1 | 741 | 13 | 746 | 14 |
| 2-4 | 806 | 14 | 792 | 14 |
| 5-9 | 380 | 7 | 451 | 8 |
| 10+ | 235 | 4 | 295 | 5 |
| Tumour size, mm | ||||
| <10 | 625 | 11 | 485 | 9 |
| 10-19 | 2,310 | 41 | 2,136 | 39 |
| 20-29 | 1,627 | 29 | 1,566 | 29 |
| 30-49 | 845 | 15 | 923 | 17 |
| 50+ | 287 | 5 | 358 | 7 |
| Grade | ||||
| I | 1,005 | 18 | 1,017 | 19 |
| II | 2,927 | 51 | 2,442 | 45 |
| III | 1,762 | 31 | 2,009 | 37 |
| ER Status | ||||
| ER negative | 991 | 17 | 1,116 | 20 |
| ER positive | 4,703 | 83 | 4,352 | 80 |
| Adjuvant therapy | ||||
| None | 643 | 11 | 1,520 | 28 |
| Chemotherapy only | 783 | 14 | 1,542 | 28 |
| Endocrine therapy | 3,146 | 55 | 1,827 | 33 |
| Combined chemoendocrine | 1,122 | 20 | 579 | 11 |
| Screen detected | ||||
| Yes | 1,621 | 28 | 1,256 | 23 |
| No | 4,073 | 72 | 4,212 | 77 |
*Follow-up censored at 8 years
†Range of variable
‡95 CI
See related research by Wishhart et al., http://breast-cancer-research.com/content/12/1/R1
References
- Wishart GC, Azzato EM, Greenberg DC, Rashbass J, Kearins O, Lawrence G, Caldas C, Pharoah PD. PREDICT: a new UK prognostic model that predicts survival following surgery for invasive breast cancer. Breast Cancer Res. 2010;12:R1. doi: 10.1186/bcr2464. [DOI] [PMC free article] [PubMed] [Google Scholar]
