Skip to main content
Cardiovascular Diseases logoLink to Cardiovascular Diseases
. 1981 Dec;8(4):475–479.

Thoracic aortic thrombi and hypercoagulability

Michael A Graham 1, Donald B Butler 1, John D Milam 1
PMCID: PMC287985  PMID: 15216174

Abstract

This unusual report shows the association between thoracic aortic mural thrombus formation and the hypercoagulable state without concomitant disseminated intravascular coagulation. The patient's hypercoagulability was reflected by laboratory results that included elevated Factor VIII and fibrinogen levels, along with a decreased level of antithrombin III. The underlying cause was probably acute peritonitis, a condition associated with coagulopathy.

Full text

PDF
475

Images in this article

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. CRAWFORD T., DEXTER D., TEARE R. D. Coronary-artery pathology in sudden death from myocardial ischaemia. A comparison by age-groups. Lancet. 1961 Jan 28;1(7170):181–185. doi: 10.1016/s0140-6736(61)91363-0. [DOI] [PubMed] [Google Scholar]
  2. Dube B., Bhatnagar B. N., Rao K. S. Blood coagulation profile in patients with acute diffuse peritonitis. Am Surg. 1978 Sep;44(9):594–598. [PubMed] [Google Scholar]
  3. Futrakul P., Poshyachinda M., Mitrakul C. Focal sclerosing glomerulonephritis: a kinetic evaluation of hemostasis and the effect of anticoagulant therapy: a controlled study. Clin Nephrol. 1978 Nov;10(5):180–186. [PubMed] [Google Scholar]
  4. Gomperts E. D., Judelman J. J., Hockley J., Mindel A., Goldberg R. B., Meyers A. M., Salant D. J., Joffe B. I., Myburgh J. A., Seftel H. C. Coagulation studies in long-term survivors after renal allograft transplantation. S Afr Med J. 1976 Jul 31;50(33):1284–1287. [PubMed] [Google Scholar]
  5. Heene D. L., Matthias F. R. Detection of thrombin-induced fibrinogen derivatives in thrombotic states. Bibl Haematol. 1977;44:161–168. doi: 10.1159/000402168. [DOI] [PubMed] [Google Scholar]
  6. Losito R., Beaudry P., Valderrama J. C., Cousineau L., Longpré B. Antithrombin III and Factor VIII in patients with neoplasms. Am J Clin Pathol. 1977 Aug;68(2):258–262. doi: 10.1093/ajcp/68.2.258. [DOI] [PubMed] [Google Scholar]
  7. Oliver D. O. Embolism from mural thrombus in the thoracic aorta. Br Med J. 1967 Sep 9;3(5566):655–656. doi: 10.1136/bmj.3.5566.655. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Peters T. G., Lewis J. D., Flip D. J., Morris L. Antithrombin III deficiency causing postsplenectomy mesenteric venous thrombosis coincident with thrombocytopenia. Ann Surg. 1977 Feb;185(2):229–231. doi: 10.1097/00000658-197702000-00017. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Planner R. S., O'Sullivan E. F., Campbell J. J., Ball D. L. The hypercoagulable state and pulmonary embolism in patients with ovarian carcinoma. Aust N Z J Obstet Gynaecol. 1978 Aug;18(3):209–212. doi: 10.1111/j.1479-828x.1978.tb00052.x. [DOI] [PubMed] [Google Scholar]
  10. Prentice C. R., McNicol G. P., Douglas A. S. Effects on blood coagulation, fibrinolysis, and platelet aggregation of normal and atheronatous aortic tissue. J Clin Pathol. 1966 Mar;19(2):154–158. doi: 10.1136/jcp.19.2.154. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Spaet T. H., Gaynor E., Stemerman M. B. Thrombosis, atherosclerosis, and endothelium. Am Heart J. 1974 May;87(5):661–668. doi: 10.1016/0002-8703(74)90507-9. [DOI] [PubMed] [Google Scholar]

Articles from Cardiovascular Diseases are provided here courtesy of Texas Heart Institute

RESOURCES