Skip to main content
PMC home page
Journal of Virology logoLink to Journal of Virology
. 1980 Apr;34(1):168–177. doi: 10.1128/jvi.34.1.168-177.1980

Specific antigenic relationships between the RNA-dependent DNA polymerases of avian reticuloendotheliosis viruses and mammalian type C retroviruses.

G Bauer, H M Temin
PMCID: PMC288683  PMID: 6154804

Abstract

Immunoglobulin G directed against the DNA polymerase of Rauscher murine leukemia virus (R-MuLV) could bind to 125I-labeled DNA polymerase of spleen necrosis virus (SNV), a member of the reticuloendotheliosis virus (REV) species. Competition radioimmunoassays showed the specificity of this cross-reaction. The antigenic determinants common to SNV and R-MuLV DNA polymerases were shared completely by the DNA polymerases of Gross MuLV, Moloney MuLV, RD 114 virus, REV-T, and duck infectious anemia virus. Baboon endogenous virus and chicken syncytial virus competed partially for antibodies directed against the common antigenic determinants of SNV and R-MuLV DNA polymerases. DNA polymerases of avian leukosis viruses, pheasant viruses, and mammalian type B and D retroviruses and particles with RNA-dependent DNA polymerase activity from the allantoic fluid of normal chicken eggs and from the medium of a goose cell culture did not compete for the antibodies directed against the common antigenic determinants of SNV and R-MuLV DNA polymerases. We also present data about a factor in normal mammalian immunoglobulin G that specifically inhibits the DNA polymerases of REV and mammalian type C retrovirus DNA polymerases.

Full text

PDF
168

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Aoki T., Walling M. J., Bushar G. S., Liu M., Hsu K. C. Natural antibodies in sera from healthy humans to antigens on surfaces of type C RNA viruses and cells from primates. Proc Natl Acad Sci U S A. 1976 Jul;73(7):2491–2495. doi: 10.1073/pnas.73.7.2491. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Barbacid M., Hunter E., Aaronson S. A. Avian reticuloendotheliosis viruses: evolutionary linkage with mammalian type C retroviruses. J Virol. 1979 May;30(2):508–514. doi: 10.1128/jvi.30.2.508-514.1979. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Bauer G., Hofschneider P. H. An RNA-dependent DNA polymerase, different from the known viral reverse transcriptases, in the chicken system. Proc Natl Acad Sci U S A. 1976 Sep;73(9):3025–3029. doi: 10.1073/pnas.73.9.3025. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Bauer G., Temin H. M. RNA-directed DNA polymerase from particles released by normal goose cells. J Virol. 1979 Mar;29(3):1006–1013. doi: 10.1128/jvi.29.3.1006-1013.1979. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Bauer G., Temin H. M. Radioimmunological comparison of the DNA polymerases of avian retroviruses. J Virol. 1980 Mar;33(3):1046–1057. doi: 10.1128/jvi.33.3.1046-1057.1980. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Charman H. P., Gilden R. V., Oroszlan S. Reticuloendotheliosis virus: detection of immunological relationship to mammalian type C retroviruses. J Virol. 1979 Mar;29(3):1221–1225. doi: 10.1128/jvi.29.3.1221-1225.1979. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Halpern M. S., Wade E., Rucker E., Baxter-Gabbard K. L., Levine A. S., Friis R. R. A study of the relationship of reticuloendotheliosis virus to the avian leukosis-sarcoma complex of viruses. Virology. 1973 Jun;53(2):287–299. doi: 10.1016/0042-6822(73)90206-7. [DOI] [PubMed] [Google Scholar]
  8. Hanafusa T., Hanafusa H., Metroka C. E., Hayward W. S., Rettenmier C. W., Sawyer R. C., Dougherty R. M., Distefano H. S. Pheasant virus: new class of ribodeoxyvirus. Proc Natl Acad Sci U S A. 1976 Apr;73(4):1333–1337. doi: 10.1073/pnas.73.4.1333. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Hunter E., Bhown A. S., Bennett J. C. Amino-terminal amino acid sequence of the major structural polypeptides of avian retroviruses: sequence homology between reticuloendotheliosis virus p30 and p30s of mammalian retroviruses. Proc Natl Acad Sci U S A. 1978 Jun;75(6):2708–2712. doi: 10.1073/pnas.75.6.2708. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Kang C. Y., Temin H. M. Lack of sequence homology among RNAs of avian leukosis-sarcoma viruses, reticuloendotheliosis viruses, and chicken endogenous RNA-directed DNA polymerase activity. J Virol. 1973 Dec;12(6):1314–1324. doi: 10.1128/jvi.12.6.1314-1324.1973. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Kang C. Y., Temin H. M. Reticuloendotheliosis virus nucleic acid sequences in cellular DNA. J Virol. 1974 Nov;14(5):1179–1188. doi: 10.1128/jvi.14.5.1179-1188.1974. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Kurth R., Teich N. M., Weiss R., Oliver R. T. Natural human antibodies reactive with primate type-C viral antigens. Proc Natl Acad Sci U S A. 1977 Mar;74(3):1237–1241. doi: 10.1073/pnas.74.3.1237. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. LOWRY O. H., ROSEBROUGH N. J., FARR A. L., RANDALL R. J. Protein measurement with the Folin phenol reagent. J Biol Chem. 1951 Nov;193(1):265–275. [PubMed] [Google Scholar]
  14. Maldonado R. L., Bose H. R., Jr Group-specific antigen shared by the members of the reticuloendotheliosis virus complex. J Virol. 1976 Mar;17(3):983–990. doi: 10.1128/jvi.17.3.983-990.1976. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Maldonado R. L., Bose H. R. Relationship of reticuloendotheliosis virus to the avian tumor viruses: nucleic acid and polypeptide composition. J Virol. 1973 May;11(5):741–747. doi: 10.1128/jvi.11.5.741-747.1973. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Mizutani A., Temin H. M. Purification and properties of spleen necrosis virus DNA polymerase. J Virol. 1975 Oct;16(4):797–806. doi: 10.1128/jvi.16.4.797-806.1975. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Mizutani S., Temin H. M. Lack of serological relationship among DNA polymerases of avian leukosis-sarcoma viruses, reticuloendotheliosis viruses, and chicken cells. J Virol. 1973 Sep;12(3):440–448. doi: 10.1128/jvi.12.3.440-448.1973. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Mizutani S., Temin H. M. Specific serological relationships among partially purified DNA polymerases of avian leukosis-sarcoma viruses, reticuloendotheliosis viruses, and avian cells. J Virol. 1974 May;13(5):1020–1029. doi: 10.1128/jvi.13.5.1020-1029.1974. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Moelling K., Gelderblom H., Pauli G., Friis R. A comparative study of the avian reticuloendotheliosis virus: relationship to murine leukemia virus and viruses of the avian sarcoma-leukosis complex. Virology. 1975 Jun;65(2):546–557. doi: 10.1016/0042-6822(75)90059-8. [DOI] [PubMed] [Google Scholar]
  20. Purchase H. G., Ludford C., Nazerian K., Cox H. W. A new group of oncogenic viruses: reticuloendotheliosis, chick syncytial, duck infectious anemia, and spleen necrosis viruses. J Natl Cancer Inst. 1973 Aug;51(2):489–499. [PubMed] [Google Scholar]
  21. Purchase H. G., Witter R. L. The reticuloendotheliosis viruses. Curr Top Microbiol Immunol. 1975;71:103–124. doi: 10.1007/978-3-642-66193-8_3. [DOI] [PubMed] [Google Scholar]
  22. Snyder H. W., Jr, Pincus T., Fleissner E. Specificities of human immunoglobulins reactive with antigens in preparations of several mammalian type-C viruses. Virology. 1976 Nov;75(1):60–73. doi: 10.1016/0042-6822(76)90007-6. [DOI] [PubMed] [Google Scholar]
  23. Zeigel R. F., Theilen G. H., Twiehaus M. J. Electron microscopic observations on RE virus (strain T) that induces reticuloendotheliosis in turkeys, chickens, and Japanese quail. J Natl Cancer Inst. 1966 Dec;37(6):709–729. [PubMed] [Google Scholar]

Articles from Journal of Virology are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES