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. 1980 Jul;35(1):252–255. doi: 10.1128/jvi.35.1.252-255.1980

Phenotype of polyoma-induced hamster tumor cells lines.

M A Israel, M A Martin, T Miyamura, K K Takemoto, D Rifkin, R Pollack
PMCID: PMC288802  PMID: 6251273

Abstract

Cell lines from polyoma-induced hamster tumors exhibit a fully transformed phenotype despite the absence of the 105K (105,000-dalton) form of polyoma T-antigen.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Di Mayorca G., Callender J., Marin G., Giordano R. Temperature-sensitive mutants of polyoma virus. Virology. 1969 May;38(1):126–133. doi: 10.1016/0042-6822(69)90134-2. [DOI] [PubMed] [Google Scholar]
  2. Eckhart W. Complementation and transformation by temperature-sensitive mutants of polyoma virus. Virology. 1969 May;38(1):120–125. doi: 10.1016/0042-6822(69)90133-0. [DOI] [PubMed] [Google Scholar]
  3. FRIED M. CELL-TRANSFORMING ABILITY OF A TEMPERATURE-SENSITIVE MUTANT OF POLYOMA VIRUS. Proc Natl Acad Sci U S A. 1965 Mar;53:486–491. doi: 10.1073/pnas.53.3.486. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Fluck M. M., Benjamin T. L. Comparisons of two early gene functions essential for transformation in polyoma virus and SV-40. Virology. 1979 Jul 15;96(1):205–228. doi: 10.1016/0042-6822(79)90185-5. [DOI] [PubMed] [Google Scholar]
  5. Folk W. R. Induction of virus synthesis in polyoma-transformed BHK-21 cells. J Virol. 1973 Mar;11(3):424–431. doi: 10.1128/jvi.11.3.424-431.1973. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Hutchinson M. A., Hunter T., Eckhart W. Characterization of T antigens in polyoma-infected and transformed cells. Cell. 1978 Sep;15(1):65–77. doi: 10.1016/0092-8674(78)90083-1. [DOI] [PubMed] [Google Scholar]
  7. Imada M., Sueoka N., Rifkin D. B. Clonal sublines of rat neurotumor RT4 and cell differentiation. II. A conversion coupling of tumorigenicity and a glial property. Dev Biol. 1978 Sep;66(1):109–116. doi: 10.1016/0012-1606(78)90277-4. [DOI] [PubMed] [Google Scholar]
  8. Israel M. A., Chan H. W., Hourihan S. L., Rowe W. P., Martin M. A. Biological activity of polyoma viral DNA in mice and hamsters. J Virol. 1979 Mar;29(3):990–996. doi: 10.1128/jvi.29.3.990-996.1979. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Israel M. A., Simmons D. T., Hourihan S. L., Rowe W. P., Martin M. A. Interrupting the early region of polyoma virus DNA enhances tumorigenicity. Proc Natl Acad Sci U S A. 1979 Aug;76(8):3713–3716. doi: 10.1073/pnas.76.8.3713. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Ossowski L., Unkeless J. C., Tobia A., Quigley J. P., Rifkin D. B., Reich E. An enzymatic function associated with transformation of fibroblasts by oncogenic viruses. II. Mammalian fibroblast cultures transformed by DNA and RNA tumor viruses. J Exp Med. 1973 Jan 1;137(1):112–126. doi: 10.1084/jem.137.1.112. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Pollack R., Risser R., Conlon S., Rifkin D. Plasminogen activator production accompanies loss of anchorage regulation in transformation of primary rat embryo cells by simian virus 40. Proc Natl Acad Sci U S A. 1974 Dec;71(12):4792–4796. doi: 10.1073/pnas.71.12.4792. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Rifkin D. B., Pollack R. Production of plasminogen activator by established cell lines of mouse origin. J Cell Biol. 1977 Apr;73(1):47–55. doi: 10.1083/jcb.73.1.47. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Risser R., Pollack R. Factors affecting the frequency of transformation of rat embryo cells by simian virus 40. Virology. 1979 Jan 15;92(1):82–90. doi: 10.1016/0042-6822(79)90216-2. [DOI] [PubMed] [Google Scholar]
  14. Risser R., Rifkin D., Pollack R. The stable classes of transformed cells induced by SV40 infection of established 3T3 cells and primary rat embryonic cells. Cold Spring Harb Symp Quant Biol. 1975;39(Pt 1):317–324. doi: 10.1101/sqb.1974.039.01.042. [DOI] [PubMed] [Google Scholar]
  15. Vogt M. Induction of virus multiplication in 3T3 cells transformed by a thermosensitive mutant of polyoma virus. I. Isolation and characterization of Ts-a-3T3 cells. J Mol Biol. 1970 Feb 14;47(3):307–316. doi: 10.1016/0022-2836(70)90304-9. [DOI] [PubMed] [Google Scholar]

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