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. 1980 Jul;35(1):259–264. doi: 10.1128/jvi.35.1.259-264.1980

Three independent isolates of feline sarcoma virus code for three distinct gag-x polyproteins.

S K Ruscetti, L P Turek, C J Sherr
PMCID: PMC288804  PMID: 6251274

Abstract

Cells nonproductively transformed by the Snyder-Theilen, Gardner-Arnstein, and McDonough strains of feline sarcoma virus synthesize gag-x polyproteins of 78,000, 100,000, and 180,000 daltons, respectively. These feline sarcoma virus-coded products were precipitated by antisera to polypeptides encoded by the gag gene of feline leukemia virus and by rat antisera raised to feline sarcoma virus-transformed rat tumor cells. Precipitation with rat antisera absorbed with feline leukemia virus showed that the x-portions of the three gag-x proteins were each antigenically distinct, suggesting that the src genes of the three independent isolates are not identical. Anti-x sera did not precipitate products from radiolabeled cat lymphoid tumor cells (FL74) and therefore lacked reactivity to the feline leukemia virus-induced tumor-specific antigen, FOCMA.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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