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Journal of Virology logoLink to Journal of Virology
. 1980 Sep;35(3):741–747. doi: 10.1128/jvi.35.3.741-747.1980

Black Beetle Virus: Propagation in Drosophila Line 1 Cells and an Infection-Resistant Subline Carrying Endogenous Black Beetle Virus-Related Particles

Paul Friesen 1, Paul Scotti 2, John Longworth 2, Roland Rueckert 1
PMCID: PMC288868  PMID: 16789201

Abstract

Black beetle virus (BBV), one of a recently discovered class of viruses with a bipartite genome, multiplied readily in Schneider's line 1 of Drosophila cells. Virus yields, on the order of 100 mg per liter of culture, were unusually high and represented some 20% of the total cell protein within 3 days after infection. A derivative subline of these Drosophila cells was found to be resistant to infection by BBV. These resistant cells were also found to carry small amounts of BBV-related particles, possibly a maturation-defective form of BBV.

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Selected References

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