TABLE 1.
Body weight (g) |
Blood glucose (mmol/l) |
|||||||
---|---|---|---|---|---|---|---|---|
C-C | C-R | D-C | D-R | C-C | C-R | D-C | D-R | |
Week 0 | 28.3 ± 0.3 | 27.7 ± 0.5 | 21.2 ± 0.5 | 20.4 ± 0.4 | 8.7 ± 0.1 | 9.0 ± 0.3 | 25.4 ± 0.8 | 27.5 ± 0.9 |
Week 2 | 27.6 ± 0.3 | 26.3 ± 0.4 | 21.1 ± 0.6 | 21.1 ± 0.5 | 9.0 ± 0.2 | 7.4 ± 0.2 | 31.8 ± 0.7 | 29.6 ± 0.8 |
Week 4 | 28.5 ± 0.3 | 27.8 ± 0.4 | 20.6 ± 0.6 | 21.2 ± 0.5 | 8.3 ± 0.2 | 7.9 ± 0.2 | 31.2 ± 0.8 | 27.7 ± 1.2* |
Data are means ± SE (n = 10). Resveratrol (in 0.5% CMC) at a dose of 20 mg/kg of body weight and 0.5% CMC alone were administered daily to control and diabetic mice, respectively, by oral gavage for 4 weeks. Time points were 0, 2, and 4 weeks after administration of resveratrol and CMC to control and diabetic mice, respectively, 1 month after STZ treatment: C-C and C-R, CMC- and resveratrol-treated control mice, respectively; D-C and D-R, CMC- and resveratrol-treated diabetic mice, respectively.
*P < 0.05 compared with CMC- and resveratrol-treated diabetic groups.