Correction for Barral et al., Coupling a sensory hair-cell bundle to cyber clones enhances nonlinear amplification

APPLIED PHYSICAL SCIENCES, BIOPHYSICS AND COMPUTATIONAL BIOLOGY Correction for “Coupling a sensory hair-cell bundle to cyber clones enhances nonlinear amplification,” by Jérémie Barral, Kai Dierkes, Benjamin Lindner, Frank Jülicher, and Pascal Martin, which appeared in issue 18, May 4, 2010, of Proc Natl Acad Sci USA (107:8079–8084; first published April 19, 2010; 10.1073/pnas.0913657107).

The authors note that due to a printer’s error, Fig. 3 appeared incorrectly. The corrected figure and its legend appear below.

Fig. 3.

Effects of coupling on nonlinear amplification. (A) Hair-bundle sensitivity as a function of the external force F_EXT without coupling (white disks) and with a coupling stiffness K = 0.2 pN/nm (black disks). (B) Hair-bundle sensitivities at F_EXT = 0.3 pN with K = 0.2 pN/nm (black disks) and without coupling (white disks) were significantly different (Student t test, P < 5.10⁻⁴). Simulations yielded sensitivities shown by thin continuous (coupled) and dashed (uncoupled) lines that were not statistically different from mean experimental values (Student t tests, P = 0.78 and P = 0.59 for coupled and uncoupled conditions, respectively). (C) Hair-bundle sensitivity at F_EXT = 0.5 pN (black disks) and F_EXT = 50 pN (white disks) as a function of coupling stiffness. Simulations yielded similar sensitivities shown by thin lines (Pearson correlation coefficient for F_EXT = 0.5 pN: R = 0.91, P = 0.03). (D) Gain of the hair-bundle amplifier at saturation with K = 0.15–0.4 pN/nm and without coupling, under normal conditions (black) and in the presence of the channel blocker gentamicin (white). Statistical significance was estimated by a Student t test (**, P < 0.01; ***, P < 0.001).