Skip to main content
PMC home page
The Journal of Clinical Investigation logoLink to The Journal of Clinical Investigation
. 1963 Jan;42(1):111–123. doi: 10.1172/JCI104688

HETEROGENEITY OF MYELOMA PROTEINS

John L Fahey 1
PMCID: PMC289255  PMID: 16695891

Full text

PDF

Images in this article

112Image
on p.112
115Image
on p.115
116Image
on p.116

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ASKONAS B. A. A study on globulin formation by plasma-cell neoplasm (5563) transplantable in mice. Biochem J. 1961 Apr;79:33–43. doi: 10.1042/bj0790033. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. ASKONAS B. A., FAHEY J. L. An investigation of closely related gamma-myeloma proteins and normal mouse gamma-globbulin by partial enzymic degradation and starch-gel electrophoresis. Nature. 1961 Jun 10;190:980–983. doi: 10.1038/190980a0. [DOI] [PubMed] [Google Scholar]
  3. CREYSSEL R., FINE J. M., MOREL P. [Biochemical study of various atypical forms of dysproteinemia]. Rev Hematol. 1959 Jul-Sep;14:238–249. [PubMed] [Google Scholar]
  4. DEUTSCH H. F., MORTON J. I. Human serum macroglobulins and dissociation units. I. Physicochemical properties. J Biol Chem. 1958 Apr;231(2):1107–1118. [PubMed] [Google Scholar]
  5. EARLE D. P., HUTT M. P., SCHMID K., GITLIN D. Observations on double albumin: a genetically transmitted serum protein anomaly. J Clin Invest. 1959 Aug;38(8):1412–1420. doi: 10.1172/JCI103917. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. ENGLE R. L., Jr, WOODS K. R., CASTILLO G. B., PERT J. H. Starch gel electrophoresis of serum proteins and urinary proteins from patients with multiple myeloma, macroglobulinemia, and other forms of dysproteinemia. Demonstration of diversity and complexity of protein alterations in 72 cases. J Lab Clin Med. 1961 Jul;58:1–22. [PubMed] [Google Scholar]
  7. FAHEY J. L. Chromatographic studies of anomalous gamma-, beta2a-, and macroblobulins and normal gamma-globulins in myeloma and macroglobulinemic sera. J Biol Chem. 1962 Feb;237:440–445. [PubMed] [Google Scholar]
  8. FAHEY J. L., HORBETT A. P. Human gamma globulin fractionation on anion exchange cellulose columns. J Biol Chem. 1959 Oct;234:2645–2651. [PubMed] [Google Scholar]
  9. FAHEY J. L. Physiocochemical characterization of mouse myeloma proteins: demonstration of heterogeneity for each myeloma globulin. J Exp Med. 1961 Sep 1;114:399–413. doi: 10.1084/jem.114.3.399. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. FLYNN F. V., STOW E. A. Fractionation of Bence-Jones protein by starch gel electrophoresis. J Clin Pathol. 1958 Jul;11(4):334–338. doi: 10.1136/jcp.11.4.334. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. GRABAR P., FAUVERT R., BURTIN P., HARTMANN L. Etude sur les protéines du myélome. II. L'analyse immuno-électrophorétique des sérums de 30 malades. Rev Fr Etud Clin Biol. 1956 Feb;1(2):175–187. [PubMed] [Google Scholar]
  12. HEREMANS J. F., HEREMANS M. T., SCHULTZE H. E. Isolation and description of a few properties of the beta 2A-globulin of human serum. Clin Chim Acta. 1959 Jan;4(1):96–102. doi: 10.1016/0009-8981(59)90088-9. [DOI] [PubMed] [Google Scholar]
  13. INGRAM V. M. Chemistry of the abnormal human haemoglobins. Br Med Bull. 1959 Jan;15(1):27–32. doi: 10.1093/oxfordjournals.bmb.a069709. [DOI] [PubMed] [Google Scholar]
  14. Kekwick R. A. The serum proteins in multiple myelomatosis. Biochem J. 1940 Sep;34(8-9):1248–1257. doi: 10.1042/bj0341248. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. LEWIS L. A., BORTZ D. W., BATTLE J. D., Jr Electrophoretic and ultracentrifugal analysis of serum proteins in multiple myeloma. Cleve Clin Q. 1951 Apr;18(2):119–126. doi: 10.3949/ccjm.18.2.119. [DOI] [PubMed] [Google Scholar]
  16. McCONNELL R. J., MARTIN N. H. The myeloma globulins. Br J Cancer. 1958 Jun;12(2):264–274. doi: 10.1038/bjc.1958.32. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. OWEN J. A., GOT C., SILBERMAN H. J. Heterogeneity of serum myeloma globulins. Clin Chim Acta. 1958 Nov;3(6):605–607. doi: 10.1016/0009-8981(58)90015-9. [DOI] [PubMed] [Google Scholar]
  18. PETERMANN M. L., HAMILTON M. G., KORNGOLD L. Multiple-myeloma proteins. II. Ultracentrigugal and electrophoretic analysis of a paucidisperse myeloma globulin. Cancer. 1956 Jan-Feb;9(1):193–194. doi: 10.1002/1097-0142(195601/02)9:1<193::aid-cncr2820090120>3.0.co;2-l. [DOI] [PubMed] [Google Scholar]
  19. POTTER M., FAHEY J. L. Studies on eight transplantable plasma-cell neoplasms of mice. J Natl Cancer Inst. 1960 May;24:1153–1165. [PubMed] [Google Scholar]
  20. POTTER M. Plasma cell neoplasia in a single host: a mosaic of different protein-producing cell types. J Exp Med. 1962 Feb 1;115:339–356. doi: 10.1084/jem.115.2.339. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. POULIK M. D. Starch gel electrophoresis in a discontinous system of buffers. Nature. 1957 Dec 28;180(4600):1477–1479. doi: 10.1038/1801477a0. [DOI] [PubMed] [Google Scholar]
  22. POULIK M. D. Starch-gel immunoelectrophoresis. J Immunol. 1959 Jun;82(6):502–515. [PubMed] [Google Scholar]
  23. PUTNAM F. W. Aberrations of protein metabolism in multiple myeloma; interrelationships of abnormal serum globulins and Bence-Jones proteins. Physiol Rev. 1957 Oct;37(4):512–538. doi: 10.1152/physrev.1957.37.4.512. [DOI] [PubMed] [Google Scholar]
  24. PUTNAM F. W., UDIN B. Proteins in multiple myeloma. I. Physicochemical study of serum proteins. J Biol Chem. 1953 Jun;202(2):727–743. [PubMed] [Google Scholar]
  25. RUNDLES R. W., COOPER G. R., WILLETT R. W. Multiple myeloma. IV. Abnormal serum components and Bence Jones protein. J Clin Invest. 1951 Oct;30(10):1125–1142. doi: 10.1172/JCI102533. [DOI] [PMC free article] [PubMed] [Google Scholar]
  26. SMITHIES O. An improved procedure for starch-gel electrophoresis: further variations in the serum proteins of normal individuals. Biochem J. 1959 Mar;71(3):585–587. doi: 10.1042/bj0710585. [DOI] [PMC free article] [PubMed] [Google Scholar]
  27. TENNENT D. M., HASHIM S. A., VAN ITALLIE T. B. Bile-acid sequestrants and lipid metabolism. Fed Proc. 1962 Jul-Aug;21(4):77–80. [PubMed] [Google Scholar]

Articles from Journal of Clinical Investigation are provided here courtesy of American Society for Clinical Investigation

RESOURCES