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. 1963 May;42(5):696–706. doi: 10.1172/JCI104761

RELATION OF ACUTE POTASSIUM DEPLETION TO RENAL AMMONIUM METABOLISM IN PATIENTS WITH CIRRHOSIS*

Juan M Baertl 1,†, Salvatore M Sancetta 1, George J Gabuzda 1,‡
PMCID: PMC289335  PMID: 13966067

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. AMATUZIO D. S., STUTZMAN F., SHRIFTER N., NESBITT S. A study of serum electrolytes (Na, K, Ca, P) in patients with severely decompensated portal cirrhosis of the liver. J Lab Clin Med. 1952 Jan;39(1):26–29. [PubMed] [Google Scholar]
  2. ARTMAN E. L., WISE R. A. Hypokalemia in liver cell failure. Am J Med. 1953 Oct;15(4):459–467. doi: 10.1016/0002-9343(53)90136-3. [DOI] [PubMed] [Google Scholar]
  3. CLARKE E., EVANS B. M., MACINTYRE I., MILNE M. D. Acidosis in experimental electrolyte depletion. Clin Sci. 1955 Aug;14(3):421–440. [PubMed] [Google Scholar]
  4. COTLOVE E., TRANTHAM H. V., BOWMAN R. L. An instrument and method for automatic, rapid, accurate, and sensitive titration of chloride in biologic samples. J Lab Clin Med. 1958 Mar;51(3):461–468. [PubMed] [Google Scholar]
  5. GABUZDA G. J., Jr, PHILLIPS G. B., DAVIDSON C. S. Reversible toxic manifestations in patients with cirrhosis of the liver given cation-exchange resins. N Engl J Med. 1952 Jan 24;246(4):124–130. doi: 10.1056/NEJM195201242460402. [DOI] [PubMed] [Google Scholar]
  6. HUTH E. J., SQUIRES R. D., ELKINTON J. R. Experimental potassium depletion in normal human subjects. II. Renal and hormonal factors in the development of extracellular alkalosis during depletion. J Clin Invest. 1959 Jul;38(7):1149–1165. doi: 10.1172/JCI103891. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. IACOBELLIS M., MUNTWYLER E., GRIFFIN G. E. Kidney glutaminase and carbonic anhydrase activity and tissue electrolyte composition in potassium-deficient dogs. Am J Physiol. 1955 Dec;183(3):395–400. doi: 10.1152/ajplegacy.1955.183.3.395. [DOI] [PubMed] [Google Scholar]
  8. MACKIE J. E., STORMONT J. M., HOLLISTER R. M., DAVIDSON C. S. Production of impending hepatic coma by chlorothiazide und its prevention by antibiotics. N Engl J Med. 1958 Dec 11;259(24):1151–1156. doi: 10.1056/NEJM195812112592402. [DOI] [PubMed] [Google Scholar]
  9. MUNTWYLER E., IACOBELLIS M., GRIFFIN G. E. Kidney glutaminase and carbonic anhydrase activities and renal electrolyte excretion in rats. Am J Physiol. 1956 Jan;184(1):83–90. doi: 10.1152/ajplegacy.1955.184.1.83. [DOI] [PubMed] [Google Scholar]
  10. McDERMOTT W. V., Jr, ADAMS R. D. Episodic stupor associated with an Eck fistula in the human with particular reference to the metabolism of ammonia. J Clin Invest. 1954 Jan;33(1):1–9. doi: 10.1172/JCI102862. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. McDERMOTT W. V., Jr, ADAMS R. D., RIDDELL A. G. Ammonia metabolism in man. Ann Surg. 1954 Oct;140(4):539–556. doi: 10.1097/00000658-195410000-00010. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. OWEN E. E., TYOR M. P., FLANAGAN J. F., BERRY J. N. The kidney as a source of blood ammonia in patients with liver disease: the effect of acetazolamide. J Clin Invest. 1960 Feb;39:288–294. doi: 10.1172/JCI104039. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. OWINGS R. H., MANDEL E. E., JONES F. Studies in non-protein nitrogen. I. A convenient method for measuring urea in blood. Proc Soc Exp Biol Med. 1951 Nov;78(2):363–366. doi: 10.3181/00379727-78-19073. [DOI] [PubMed] [Google Scholar]
  14. POSNER J. B., PLUM F. The toxic effects of carbon dioxide and acetazolamide in hepatic encephalopathy. J Clin Invest. 1960 Aug;39:1246–1258. doi: 10.1172/JCI104140. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. READ A. E., LAIDLAW J., HASLAM R. M., SHERLOCK S. Neuropsychiatric complications following chlorothiazide therapy in patients with hepatic cirrhosis: possible relation to hypokalaemia. Clin Sci. 1959 Aug;18:409–423. [PubMed] [Google Scholar]
  16. SCHWARTZ R., PHILLIPS G. B., GABUZDA G. J., Jr, DIVIDSON C. S. Blood ammonia and electrolytes in hepatic coma. J Lab Clin Med. 1953 Oct;42(4):499–508. [PubMed] [Google Scholar]
  17. SCHWARTZ W. B., JENSON R. L., RELMAN A. S. The disposition of acid administered to sodium-depleted subjects: the renal response and the role of the whole body buffers. J Clin Invest. 1954 Apr;33(4):587–597. doi: 10.1172/JCI102930. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. SCHWARTZ W. B., RELMAN A. S. Metabolic and renal studies in chronic potassium depletion resulting from overuse of laxatives. J Clin Invest. 1953 Mar;32(3):258–271. doi: 10.1172/JCI102735. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. SHERLOCK S. Pathogenesis and management of hepatic coma. Am J Med. 1958 May;24(5):805–813. doi: 10.1016/0002-9343(58)90382-6. [DOI] [PubMed] [Google Scholar]
  20. Sartorius O. W., Roemmelt J. C., Pitts R. F., Calhoon D., Miner P. THE RENAL REGULATION OF ACID-BASE BALANCE IN MAN. IV. THE NATURE OF THE RENAL COMPENSATIONS IN AMMONIUM CHLORIDE ACIDOSIS. J Clin Invest. 1949 May;28(3):423–439. doi: 10.1172/JCI102087. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. WEBSTER L. T., Jr, DAVIDSON C. S., GABUZDA G. J. Effect on portal blood ammonium of administering nitrogenous substances to patients with chronic hepatic disease. J Lab Clin Med. 1958 Oct;52(4):501–514. [PubMed] [Google Scholar]
  22. WHITE L. P., PHEAR E. A., SUMMERSKILL W. H., SHERLOCK S. Ammonium tolerance in liver disease: observations based on catheterization of the hepatic veins. J Clin Invest. 1955 Feb;34(2):158–168. doi: 10.1172/JCI103070. [DOI] [PMC free article] [PubMed] [Google Scholar]

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