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. 1964 May;43(5):894–903. doi: 10.1172/JCI104975

Abnormal Tryptophan Metabolism in Patients with Adult Celiac Disease, with Evidence for Deficiency of Vitamin B6*

O Dhodanand Kowlessar 1,†, Lorraine J Haeffner 1,‡, Gordon D Benson 1,§
PMCID: PMC289568  PMID: 14169518

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BOYER P. H., ANDERSEN D. H. A genetic study of celiac disease; incidence of celiac disease, gastrointestinal disorders, and diabetes in pedigrees of children with celiac disease. AMA J Dis Child. 1956 Feb;91(2):131–137. doi: 10.1001/archpedi.1956.02060020133005. [DOI] [PubMed] [Google Scholar]
  2. BOYLAND E., WILLIAMS D. C. The metabolism of tryptophan. 2. The metabolism of tryptophan in patients suffering from cancer of the bladder. Biochem J. 1956 Nov;64(3):578–582. doi: 10.1042/bj0640578. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Brown R. R., Thornton M. J., Price J. M. THE EFFECT OF VITAMIN SUPPLEMENTATION ON THE URINARY EXCRETION OF TRYPTOPHAN METABOLITES BY PREGNANT WOMEN. J Clin Invest. 1961 Apr;40(4):617–623. doi: 10.1172/JCI104292. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. CARTER C., SHELDON W., WALKER C. The inheritance of coeliac disease. Ann Hum Genet. 1959 Jul;23:266–278. doi: 10.1111/j.1469-1809.1959.tb01470.x. [DOI] [PubMed] [Google Scholar]
  5. DALGLIESH C. E. The relation between pyridoxin and tryptophan metabolism, studied in the rat. Biochem J. 1952 Sep;52(1):3–14. doi: 10.1042/bj0520003. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. FLETCHER R. F., McCRIRICK M. Y. Gluten-free diets. Br Med J. 1958 Aug 2;2(5091):299–301. doi: 10.1136/bmj.2.5091.299. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. GIRDWOOD R. H. Absorption in sprue of vitamins of the B complex. Lancet. 1956 Oct 6;271(6945):700–701. doi: 10.1016/s0140-6736(56)92386-8. [DOI] [PubMed] [Google Scholar]
  8. HAVERBACK B. J., DYCE B., THOMAS H. V. Indole metabolism in the malabsorption syndrome. N Engl J Med. 1960 Apr 14;262:754–757. doi: 10.1056/NEJM196004142621504. [DOI] [PubMed] [Google Scholar]
  9. KOWLESSAR O. D., WILLIAMS R. C., LAW D. H., SLEISENGER M. H. Urinary excretion of 5-hydroxyindolacetic acid in diarrheal states, with special reference to nontropical sprue. N Engl J Med. 1958 Aug 14;259(7):340–341. doi: 10.1056/NEJM195808142590708. [DOI] [PubMed] [Google Scholar]
  10. LOBEL S., WACHSTEIN M. The relation between tryptophane metabolism and vitamin B6 in various diseases as studied by paper chromatography. Am J Clin Pathol. 1956 Aug;26(8):910–925. doi: 10.1093/ajcp/26.8.910. [DOI] [PubMed] [Google Scholar]
  11. MILNE M. D., CRAWFORD M. A., GIRAO C. B., LOUGHRIDGE L. W. The metabolic disorder in Hartnup disease. Q J Med. 1960 Jul;29:407–421. [PubMed] [Google Scholar]
  12. MUSAJO L., BENASSI C. A., PARPAJOLA A. Excretion and isolation of kynurenine and 3-hydroxykynurenine from human pathological urine. Clin Chim Acta. 1956 May-Jun;1(3):229–235. doi: 10.1016/0009-8981(56)90069-9. [DOI] [PubMed] [Google Scholar]
  13. PARE C. M., SANDLER M., STACEY R. S. Decreased 5-hydroxytryptophan decarboxylase activity in phenylketonuria. Lancet. 1958 Nov 22;2(7056):1099–1101. doi: 10.1016/s0140-6736(58)92471-1. [DOI] [PubMed] [Google Scholar]
  14. PRICE J. M., BROWN R. R., LARSON F. C. Quantitative studies on human urinary metabolites of tryptophan as affected by isoniazid and deoxypyridoxine. J Clin Invest. 1957 Nov;36(11):1600–1607. doi: 10.1172/JCI103559. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. PRICE J. M., BROWN R. R., PETERS H. A. Tryptophan metabolism in porphyria, schizophrenia, and a variety of neurologic and psychiatric diseases. Neurology. 1959 Jul;9(7):456–468. doi: 10.1212/wnl.9.7.456. [DOI] [PubMed] [Google Scholar]
  16. PRICE J. M., BROWN R. R., RUKAVINA J. G., MENDELSON C., JOHNSON S. A. Scleroderma (acrosclerosis). II. Tryptophan metabolism before and during treatment by Chelaton (EDTA). J Invest Dermatol. 1957 Oct;29(4):289–298. [PubMed] [Google Scholar]
  17. PRICE J. M. Disorders of tryptophan metabolism. Med Bull (Ann Arbor) 1958 Dec;24(12):461–485. [PubMed] [Google Scholar]
  18. ROSS G., WEINSTEIN I. B., KABAKOW B. The influence of phenothiazine and some of its derivatives on the determination of 5-hydroxyindoleacetic acid in urine. Clin Chem. 1958 Feb;4(1):66–76. [PubMed] [Google Scholar]
  19. SATOH K., PRICE J. M. Fluorometric determination of kynurenic acid and xanthurenic acid in human urine. J Biol Chem. 1958 Feb;230(2):781–789. [PubMed] [Google Scholar]
  20. SCRIVER C. R., HUTCHISON J. H. The vitamin B6 deficiency syndrome in human infancy: biochemical and clinical observations. Pediatrics. 1963 Feb;31:240–250. [PubMed] [Google Scholar]
  21. SJOERDSMA A., WEISSBACH H., UDENFRIEND S. A clinical, physiologic and biochemical study of patients with malignant carcinoid (argentaffinoma). Am J Med. 1956 Apr;20(4):520–532. doi: 10.1016/0002-9343(56)90136-x. [DOI] [PubMed] [Google Scholar]
  22. TOMPSETT S. L. The determination in urine of some metabolites of tryptophankynurenine, anthranilic acid and 3-hydroxyanthranilic acid- and reference to the presence of o-aminophenol in urine. Clin Chim Acta. 1959 May;4(3):411–419. doi: 10.1016/0009-8981(59)90112-3. [DOI] [PubMed] [Google Scholar]
  23. UDENFRIEND S., LOVENBERG W., SJOERDSMA A. Physiologically active amines in common fruits and vegetables. Arch Biochem Biophys. 1959 Dec;85:487–490. doi: 10.1016/0003-9861(59)90516-8. [DOI] [PubMed] [Google Scholar]
  24. UDENFRIEND S., TITUS E., WEISSBACH H. The identification of 5-hydroxy-3-indoleacetic acid in normal urine and a method for its assay. J Biol Chem. 1955 Oct;216(2):499–505. [PubMed] [Google Scholar]
  25. WACHSTEIN M., GUDAITIS A. Disturbance of vitamin B6 metabolism in pregnancy. J Lab Clin Med. 1952 Oct;40(4):550–557. [PubMed] [Google Scholar]
  26. WEISSBACH H., KING W., SJOERDSMA A., UDENFRIEND S. Formation of indole-3-acetic acid and tryptamine in animals: a method for estimation of indole-3-acetic acid in tissues. J Biol Chem. 1959 Jan;234(1):81–86. [PubMed] [Google Scholar]

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