Skip to main content
PMC home page
The Journal of Clinical Investigation logoLink to The Journal of Clinical Investigation
. 1964 Jun;43(6):1146–1162. doi: 10.1172/JCI104999

The Influence of Hydrogen Ion Concentration and Hypoxia on the Pulmonary Circulation*

Yale Enson 1,†, Carlo Giuntini 1,‡, Milena L Lewis 1,§, Thomas Q Morris 1,ǁ, M Irené Ferrer 1, Réjane M Harvey 1
PMCID: PMC289596  PMID: 14171792

Full text

PDF
1146

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BERGOFSKY E. H., LEHR D. E., FISHMAN A. P. The effect of changes in hydrogen ion concentration on the pulmonary circulation. J Clin Invest. 1962 Jul;41:1492–1502. doi: 10.1172/JCI104604. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. BERMAN L. B., O'CONNOR T. F., LUCHSINGER P. C. Carbon dioxide buffering in man. J Appl Physiol. 1960 May;15:393–396. doi: 10.1152/jappl.1960.15.3.393. [DOI] [PubMed] [Google Scholar]
  3. BINET L., BURSTEIN M. Sur l'action vasoconstrictrice du sérum salé hypertonique au niveau de la petite circulation. C R Seances Soc Biol Fil. 1951 Dec;145(23-24):1766–1770. [PubMed] [Google Scholar]
  4. BINET L., BURSTEIN M. Sur les effets cardio-vasculaires du sérum salé hypertonique. C R Seances Soc Biol Fil. 1953 Dec;147(23-24):1997–2000. [PubMed] [Google Scholar]
  5. BORDEN C. W., WILSON R. H., EBERT R. V., WELLS H. S. Pulmonary hypertension in chronic pulmonary emphysema. Am J Med. 1950 Jun;8(6):701–709. doi: 10.1016/0002-9343(50)90094-5. [DOI] [PubMed] [Google Scholar]
  6. BRINKMAN G. L., REMP D. G., COATES E. O., Jr, PRIEST E. M. The treatment of respiratory acidosis with THAM. Am J Med Sci. 1960 Mar;239:341–346. doi: 10.1097/00000441-196003000-00012. [DOI] [PubMed] [Google Scholar]
  7. BRUTSAERT D., LACROIX E., LEUSEN I. [Influence of hypertonic solutions on the pulmonary circulation]. Acta Cardiol. 1960;15:273–280. [PubMed] [Google Scholar]
  8. DOYLE J. T., WILSON J. S., WARREN J. V. The pulmonary vascular responses to short-term hypoxia in human subjects. Circulation. 1952 Feb;5(2):263–270. doi: 10.1161/01.cir.5.2.263. [DOI] [PubMed] [Google Scholar]
  9. ELIAKIM M., ROSENBERG S. Z., BRAUN K. Effect of hypertonic saline on the pulmonary and systemic pressures. Circ Res. 1958 May;6(3):357–362. doi: 10.1161/01.res.6.3.357. [DOI] [PubMed] [Google Scholar]
  10. FERRER M. I., HARVEY R. M. Some effects of digoxin upon the heart and circulation in man; digoxin in chronic cor pulmonale. Circulation. 1950 Feb;1(2):161-86, illust. doi: 10.1161/01.cir.1.2.161. [DOI] [PubMed] [Google Scholar]
  11. FISHMAN A. P., FRITTS H. W., Jr, COURNAND A. Effects of acute hypoxia and exercise on the pulmonary circulation. Circulation. 1960 Aug;22:204–215. doi: 10.1161/01.cir.22.2.204. [DOI] [PubMed] [Google Scholar]
  12. FISHMAN A. P., FRITTS H. W., Jr, COURNAND A. Effects of breathing carbon dioxide upon the pulmonary circulation. Circulation. 1960 Aug;22:220–225. doi: 10.1161/01.cir.22.2.220. [DOI] [PubMed] [Google Scholar]
  13. FISHMAN A. P., McCLEMENT J., HIMMELSTEIN A., COURNAND A. Effects of acute anoxia on the circulation and respiration in patients with chronic pulmonary disease studied during the steady state. J Clin Invest. 1952 Aug;31(8):770–781. doi: 10.1172/JCI102662. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. FRITTS H. W., Jr, HARDEWIG A., ROCHESTER D. F., DURAND J., COURNAND A. Estimation of pulmonary arteriovenous shunt-flow using intravenous injections of T-1824 dye and Kr85. J Clin Invest. 1960 Dec;39:1841–1850. doi: 10.1172/JCI104208. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. GIUNTINI C., LEWIS M. L., LUIS A. S., HARVEY R. M. A STUDY OF THE PULMONARY BLOOD VOLUME IN MAN BY QUANTITATIVE RADIOCARDIOGRAPHY. J Clin Invest. 1963 Oct;42:1589–1605. doi: 10.1172/JCI104844. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. HARVEY R. M., FERRER M. I., RICHARDS D. W., Jr, COURNAND A. Influence of chronic pulmonary disease on the heart and circulation. Am J Med. 1951 Jun;10(6):719–738. doi: 10.1016/0002-9343(51)90340-3. [DOI] [PubMed] [Google Scholar]
  17. Hickam J. B., Cargill W. H. EFFECT OF EXERCISE ON CARDIAC OUTPUT AND PULMONARY ARTERIAL PRESSURE IN NORMAL PERSONS AND IN PATIENTS WITH CARDIOVASCULAR DISEASE AND PULMONARY EMPHYSEMA. J Clin Invest. 1948 Jan;27(1):10–23. doi: 10.1172/JCI101912. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. JAMESON A. G. Diffusion of gases from alveolus to precapillary arteries. Science. 1963 Mar 1;139(3557):826–828. doi: 10.1126/science.139.3557.826. [DOI] [PubMed] [Google Scholar]
  19. JORGENSEN K., ASTRUP P. The effect of 2-amino-2-hydroxy-methyl-1,3-propanediol on blood-buffering capacity. Ann N Y Acad Sci. 1961 Jun 17;92:491–499. doi: 10.1111/j.1749-6632.1961.tb44999.x. [DOI] [PubMed] [Google Scholar]
  20. LILJESTRAND G. Chemical control of the distribution of the pulmonary blood flow. Acta Physiol Scand. 1958 Dec 15;44(3-4):216–240. doi: 10.1111/j.1748-1716.1958.tb01623.x. [DOI] [PubMed] [Google Scholar]
  21. MASSARO D. J., KATZ S., LUCHSINGER P. C. The use of a carbon dioxide buffer (trishydroxymethylaminomethane) in the treatment of respiratory acidosis. Am Rev Respir Dis. 1962 Sep;86:353–359. doi: 10.1164/arrd.1962.86.3.353. [DOI] [PubMed] [Google Scholar]
  22. Noble R. P., Gregersen M. I., Porter P. M., Buckman A. BLOOD VOLUME IN CLINICAL SHOCK. I. MIXING TIME AND DISAPPEARANCE RATE OF T-1824 IN NORMAL SUBJECTS AND IN PATIENTS IN SHOCK; DETERMINATION OF PLASMA VOLUME IN MAN FROM 10-MINUTE SAMPLE. J Clin Invest. 1946 Mar;25(2):158–171. doi: 10.1172/JCI101695. [DOI] [PMC free article] [PubMed] [Google Scholar]
  23. READ R. C., JOHNSON J. A., VICK J. A., MEYER M. W. Vascular effects of hypertonic solutions. Circ Res. 1960 May;8:538–548. doi: 10.1161/01.res.8.3.538. [DOI] [PubMed] [Google Scholar]
  24. READ R. C., VICK J. A. Cholinergic-like effects of hypertonic solutions. Am J Physiol. 1961 Feb;200:233–237. doi: 10.1152/ajplegacy.1961.200.2.233. [DOI] [PubMed] [Google Scholar]
  25. ROSSIER P. H., BUHLMANN A. Cor pulmonale et pathophysiologie alvéolaire. Cardiologia. 1954;25(2-3):132–146. [PubMed] [Google Scholar]
  26. SEMLER H. J., SHEPHERD J. T., SWAN H. J. Pressor effect of hypertonic saline on pulmonary circulation. Circ Res. 1959 Nov;7:1011–1017. doi: 10.1161/01.res.7.6.1011. [DOI] [PubMed] [Google Scholar]
  27. SWANSON A. G. Potential harmful effects of treating pulmonary encephalopathy with a carbon dioxide buffering agent. Am J Med Sci. 1960 Oct;240:433–437. doi: 10.1097/00000441-196010000-00004. [DOI] [PubMed] [Google Scholar]
  28. WESTCOTT R. N., FOWLER N. O., SCOTT R. C., HAUENSTEIN V. D., McGUIRE J. Anoxia and human pulmonary vascular resistance. J Clin Invest. 1951 Sep;30(9):957–970. doi: 10.1172/JCI102517. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Journal of Clinical Investigation are provided here courtesy of American Society for Clinical Investigation

RESOURCES