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. 1965 Nov;44(11):1866–1881. doi: 10.1172/JCI105294

A circulating anticoagulant in gamma-1A-multiple myeloma: its modification by penicillin.

H I Glueck, R Hong
PMCID: PMC289687  PMID: 5843717

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ALKJAERSIG N., FLETCHER A. P., SHERRY S. Pathogenesis of the coagulation defect developing during pathological plasma proteolytic ("fibrinolytic") states. II. The significance, mechanism and consequences of defective fibrin polymerization. J Clin Invest. 1962 Apr;41:917–934. doi: 10.1172/JCI104547. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. BELL W. N., ALTON H. G. A brain extract as a substitute for platelet suspensions in the thromboplastin generation test. Nature. 1954 Nov 6;174(4436):880–881. doi: 10.1038/174880a0. [DOI] [PubMed] [Google Scholar]
  3. BIGGS R., BIDWELL E. A method for the study of antihaemophilic globulin inhibitors with reference to six cases. Br J Haematol. 1959 Oct;5:379–395. doi: 10.1111/j.1365-2141.1959.tb04049.x. [DOI] [PubMed] [Google Scholar]
  4. BIGGS R., DENSON K. W., NOSSEL H. L. A PATIENT WITH AN UNUSUAL CIRCULATING ANTICOAGULANT. Thromb Diath Haemorrh. 1964 Oct 15;12:1–11. [PubMed] [Google Scholar]
  5. BIGGS R., DOUGLAS A. S. The thromboplastin generation test. J Clin Pathol. 1953 Feb;6(1):23–29. doi: 10.1136/jcp.6.1.23. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. CRADDOCK C. G., Jr, ADAMS W. S., FIGUEROA W. G. Interference with fibrin formation in multiple myeloma by an unusual protein found in blood and urine. J Lab Clin Med. 1953 Dec;42(6):847–859. [PubMed] [Google Scholar]
  7. DRESKIN O. H., ROSENTHAL N. A hemophilia-like disease with prolonged coagulation time and a circulating anticoagulant; report of a case in a female. Blood. 1950 Jan;5(1):46–60. [PubMed] [Google Scholar]
  8. FAHEY J. L. STRUCTURAL BASIS FOR THE DIFFERENCES BETWEEN TYPE I AND TYPE II HUMAN GAMMA-GLOBULIN MOLECULES. J Immunol. 1963 Oct;91:448–459. [PubMed] [Google Scholar]
  9. FRANKLIN E. C., FUDENBERG H., MELTZER M., STANWORTH D. R. The structural basis for genetic variations of normal human gamma-globulins. Proc Natl Acad Sci U S A. 1962 Jun 15;48:914–922. doi: 10.1073/pnas.48.6.914. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. FRICK P. G. Inhibition of conversion of fibrinogen to fibrin by abnormal proteins in multiple myeloma. Am J Clin Pathol. 1955 Nov;25(11):1263–1273. doi: 10.1093/ajcp/25.11.1263. [DOI] [PubMed] [Google Scholar]
  11. FROMMEYER W. B., Jr, EPSTEIN R. D., TAYLOR F. H. L. Refractoriness in hemophilia to coagulation-promoting agents: whole blood and plasma derivatives. Blood. 1950 May;5(5):401–420. [PubMed] [Google Scholar]
  12. GLUECK H. I., HERRMANN L. G. COLD-PRECIPITABLE FIBRINOGEN, "CRYOFIBRINOGEN". Arch Intern Med. 1964 May;113:748–757. doi: 10.1001/archinte.1964.00280110128024. [DOI] [PubMed] [Google Scholar]
  13. GLUECK H. I., SUTHERLAND J. M. Inherited factor-VII defect in a Negro family. Pediatrics. 1961 Feb;27:204–213. [PubMed] [Google Scholar]
  14. GLUECK H. I. The utilization of a synthetic substrate (TAMe) to measure the plasma prothrombin in coagulation disorders. J Lab Clin Med. 1957 Jan;49(1):41–60. [PubMed] [Google Scholar]
  15. GLUECK H. I., WAYNE L., GOLDSMITH R. Abnormal calcium binding associated with hyperglobulinemia, clotting defects, and osteoporosis: a study of this relationship. J Lab Clin Med. 1962 Jan;59:40–64. [PubMed] [Google Scholar]
  16. JAMES T. N., MONTO R. W., REBUCK J. W. Thrombocytopenia and abnormal bleeding in multiple myeloma. Ann Intern Med. 1953 Dec;39(6):1281–1287. doi: 10.7326/0003-4819-39-6-1281. [DOI] [PubMed] [Google Scholar]
  17. LEITNER A., BIDWELL E., DIKE G. W. An antihaemophilic globulin (factor VIII) inhibitor: purification, characterization and reaction kinetics. Br J Haematol. 1963 Apr;9:245–258. doi: 10.1111/j.1365-2141.1963.tb05461.x. [DOI] [PubMed] [Google Scholar]
  18. LEVY H. B., SOBER H. A. A simple chromatographic method for preparation of gamma globulin. Proc Soc Exp Biol Med. 1960 Jan;103:250–252. doi: 10.3181/00379727-103-25476. [DOI] [PubMed] [Google Scholar]
  19. LEWIS J. H., MERCHANT W. R. Application of continuous flow electrophoresis to the study of the blood coagulation proteins. II. The hemophilias (A and B). J Clin Invest. 1959 Nov;38:1924–1926. doi: 10.1172/JCI103970. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. LEWIS J. H., WALTERS D., DIDISHEIM P., MERCHANT W. R. Application of continuous flow electrophoresis to the study of the blood coagulation proteins and the fibrinolytic enzyme system. I. Normal human materials. J Clin Invest. 1958 Sep;37(9):1323–1331. doi: 10.1172/JCI103721. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. LEWIS L. A., PAGE I. H. AN UNUSUAL SERUM LIPOPROTEIN-GLOBULIN COMPLEX IN A PATIENT WITH HYPERLIPEMIA. Am J Med. 1965 Feb;38:286–297. doi: 10.1016/0002-9343(65)90183-x. [DOI] [PubMed] [Google Scholar]
  22. LONG L. A., RIOPELLE J. L., FRANCOEUR M., PARE A., POIRIER P., GEORGESCO M., COLPRON G. Macroglobulinaemia; effect of macroglobulins on prothrombin conversion accelerators. Can Med Assoc J. 1955 Nov 1;73(9):726–733. [PMC free article] [PubMed] [Google Scholar]
  23. MARGOLIUS A., Jr, JACKSON D. P., RATNOFF O. D. Circulating anticoagulants: a study of 40 cases and a review of the literature. Medicine (Baltimore) 1961 May;40:145–202. [PubMed] [Google Scholar]
  24. MONTREUIL J., CHOSSON A., HAVEZ R., MULLET S. [Isolation of beta2A-globulins from human milk]. C R Seances Soc Biol Fil. 1960;154:732–736. [PubMed] [Google Scholar]
  25. Munro F. L., Munro M. P. ELECTROPHORETIC ISOLATION OF A CIRCULATING ANTICOAGULANT. J Clin Invest. 1946 Nov;25(6):814–815. doi: 10.1172/JCI101768. [DOI] [PMC free article] [PubMed] [Google Scholar]
  26. NUSSEY A. M., DAWSON D. W. Haemophilia-like disease due to an auto-antibody. Br Med J. 1957 Nov 9;2(5053):1077–1079. doi: 10.1136/bmj.2.5053.1077. [DOI] [PMC free article] [PubMed] [Google Scholar]
  27. RATNOFF O. D., MENZIE C. A new method for the determination of fibrinogen in small samples of plasma. J Lab Clin Med. 1951 Feb;37(2):316–320. [PubMed] [Google Scholar]
  28. RITZMANN S. E., COLEMAN S. L., LEVIN W. C. The effect of some mercaptanes upon a macrocryogelglobulin; modifications induced by cysteamine, penicillamine and penicillin. J Clin Invest. 1960 Aug;39:1320–1329. doi: 10.1172/JCI104149. [DOI] [PMC free article] [PubMed] [Google Scholar]
  29. RITZMANN S. E., THURM R. H., TRUAX W. E., LEVIN W. C. The syndrome of macroglobulinemia. Review of the literature and a report of two cases of macrocryogelglobulinemia. Arch Intern Med. 1960 Jun;105:939–965. [PubMed] [Google Scholar]
  30. RODMAN N. F., Jr, BARROW E. M., GRAHAM J. B. Diagnosis and control of the hemophilioid states with the partial thromboplastin time (PTT) test. Am J Clin Pathol. 1958 Jun;29(6):525–538. doi: 10.1093/ajcp/29.6.525. [DOI] [PubMed] [Google Scholar]
  31. SCHEIDEGGER J. J. Une micro-méthode de l'immuno-electrophorèse. Int Arch Allergy Appl Immunol. 1955;7(2):103–110. [PubMed] [Google Scholar]
  32. SCHUR P. H., CHRISTIAN G. D. THE ROLE OF DISULFIDE BONDS IN THE COMPLEMENT-FIXING AND PRECIPITATING PROPERTIES OF 7S RABBIT AND SHEEP ANTIBODIES. J Exp Med. 1964 Oct 1;120:531–545. doi: 10.1084/jem.120.4.531. [DOI] [PMC free article] [PubMed] [Google Scholar]
  33. SUSSMAN L. N., COHEN I. B., GITTLER R. Clinical application of simplified serum prothrombin consumption test. J Am Med Assoc. 1954 Oct 16;156(7):702–705. doi: 10.1001/jama.1954.02950070030008. [DOI] [PubMed] [Google Scholar]
  34. WEST C. D., HINRICHS V., HINKLE N. H. Quantitative determination of the serum globulins beta-2A and beta-2M by immunoelectrophoretic analysis. J Lab Clin Med. 1961 Jul;58:137–148. [PubMed] [Google Scholar]

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