Skip to main content
The Journal of Clinical Investigation logoLink to The Journal of Clinical Investigation
. 1965 Dec;44(12):1992–2002. doi: 10.1172/JCI105306

Partial purification and properties of the isoniazid transacetylase in human liver. Its relationship to the acetylation of p-aminosalicylic acid.

J W Jennne
PMCID: PMC289702  PMID: 5851956

Full text

PDF
1992

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ALBERT A. The affinity of isonicotinic hydrazide for metals. Experientia. 1953 Oct 15;9(10):370–370. doi: 10.1007/BF02167635. [DOI] [PubMed] [Google Scholar]
  2. BARTMANN K., MASSMANN W. [The blood level of INH in adults and children]. Beitr Klin Tuberk Spezif Tuberkuloseforsch. 1960;122:239–250. [PubMed] [Google Scholar]
  3. DUFOUR A. P., KNIGHT R. A., HARRIS H. W. GENETICS OF ISONIAZID METABOLISM IN CAUCASIAN, NEGRO, AND JAPANESE POPULATIONS. Science. 1964 Jul 24;145(3630):391–391. [PubMed] [Google Scholar]
  4. EVANS D. A. ENZYMES AND DRUG SENSITIVITY. ACETYLATION POLYMORPHISMS. Proc R Soc Med. 1964 Jun;57:508–511. [PMC free article] [PubMed] [Google Scholar]
  5. EVANS D. A., MANLEY K. A., McKUSICK V. A. Genetic control of isoniazid metabolism in man. Br Med J. 1960 Aug 13;2(5197):485–491. doi: 10.1136/bmj.2.5197.485. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. EVANS D. A., WHITE T. A. HUMAN ACETYLATION POLYMORPHISM. J Lab Clin Med. 1964 Mar;63:394–403. [PubMed] [Google Scholar]
  7. FRYMOYER J. W., JACOX R. F. INVESTIGATION OF THE GENETIC CONTROL OF SULFADIAZINE AND ISONIAZID METABOLISM IN THE RABBIT. J Lab Clin Med. 1963 Dec;62:891–904. [PubMed] [Google Scholar]
  8. FRYMOYER J. W., JACOX R. F. STUDIES OF GENETICALLY CONTROLLED SULFADIAZINE ACETYLATION IN RABBIT LIVERS: POSSIBLE IDENTIFICATION OF THE HETEROZYGOUS TRAIT. J Lab Clin Med. 1963 Dec;62:905–909. [PubMed] [Google Scholar]
  9. JENNE J. W., MACDONALD F. M., MENDOZA E. A study of the renal clearances, metabolic inactivation rates, and serum fall-off interaction of isoniazid and paraminosalicylic acid in man. Am Rev Respir Dis. 1961 Sep;84:371–378. doi: 10.1164/arrd.1961.84.3.371. [DOI] [PubMed] [Google Scholar]
  10. JENNE J. W. PHARMACOKINETICS AND THE DOSE OF ISONIAZID AND P-AMINOSALICYLIC ACID IN THE TREATMENT OF TUBERCULOSIS. Antibiot Chemother. 1964;12:407–432. doi: 10.1159/000386751. [DOI] [PubMed] [Google Scholar]
  11. JENNE J. W. Studies of human patterns of isoniazid metabolism using an intravenous fall-off technique with a chemical method. Am Rev Respir Dis. 1960 Jan;81:1–8. doi: 10.1164/arrd.1960.81.1.1. [DOI] [PubMed] [Google Scholar]
  12. JOHNSON W. J. The inhibition of sulphanilamide acetylation by aromatic and heterocyclic carboxamides and carboxhydrazides. Can J Biochem Physiol. 1955 Mar;33(2):107–111. [PubMed] [Google Scholar]
  13. LAUENER H., FAVEZ G. The inhibition of isoniazid inactivation by means of PAS and benzoyl-PAS in man. Am Rev Respir Dis. 1959 Jul;80(1 Pt 1):26–37. doi: 10.1164/arrd.1959.80.1P1.26. [DOI] [PubMed] [Google Scholar]
  14. LOWRY O. H., ROSEBROUGH N. J., FARR A. L., RANDALL R. J. Protein measurement with the Folin phenol reagent. J Biol Chem. 1951 Nov;193(1):265–275. [PubMed] [Google Scholar]
  15. Nelson E. Kinetic considerations in pharmacogenetic studies of drug metabolism. Life Sci. 1965 May;4(9):949–953. doi: 10.1016/0024-3205(65)90195-5. [DOI] [PubMed] [Google Scholar]
  16. PERRY H. M., Jr A method of quantitating 1-hydrazinophthalazine in body fluids. J Lab Clin Med. 1953 Apr;41(4):566–573. [PubMed] [Google Scholar]
  17. PETERS J. H., GORDON G. R., BROWN P. THE RELATIONSHIP BETWEEN THE CAPACITIES OF HUMAN SUBJECTS TO ACETYLATE ISONIAZID, SULFANILAMIDE AND SULFAMETHAZINE. Life Sci. 1965 Jan;4:99–107. doi: 10.1016/0024-3205(65)90040-8. [DOI] [PubMed] [Google Scholar]
  18. PETERS J. H. Studies on the metabolism of isoniazid. 2. The influence of para-aminosalicylic acid on the metabolism of isoniazid by man. Am Rev Respir Dis. 1960 Aug;82:153–163. doi: 10.1164/arrd.1960.82.2.153. [DOI] [PubMed] [Google Scholar]
  19. SCHULERT A. R. Physiological disposition of hydralazine (1-hydrazinophthalazine) and a method for its determination in biological fluids. Arch Int Pharmacodyn Ther. 1961 Jun 1;132:1–15. [PubMed] [Google Scholar]
  20. SUNAHARA S., URANOM, OGAWAM Genetical and geographic studies on isoniazid inactivation. Science. 1961 Nov 10;134(3489):1530–1531. doi: 10.1126/science.134.3489.1530. [DOI] [PubMed] [Google Scholar]
  21. TABOR H., MEHLER A. H., STADTMAN E. R. The enzymatic acetylation of amines. J Biol Chem. 1953 Sep;204(1):127–138. [PubMed] [Google Scholar]
  22. YARD A. S., MCKENNIS H., Jr ASPECTS OF THE METABOLISM OF ISONIAZID AND ACETYLISONIAZID IN THE HUMAN AND THE DOG. J Med Pharm Chem. 1962 Jan;5:196–203. doi: 10.1021/jm01236a019. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Clinical Investigation are provided here courtesy of American Society for Clinical Investigation

RESOURCES