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. 1960 Jan;39(1):15–20. doi: 10.1172/JCI104013

PYRIMIDINE METABOLISM IN MAN. III. STUDIES ON LEUKOCYTES AND ERYTHROCYTES IN PERNICIOUS ANEMIA*,†

Lloyd H Smith Jr 1, Faith A Baker 1
PMCID: PMC290657  PMID: 13854867

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. COLEMAN D. H., DONOHUE D. M., FINCH C. A., MOTULSKY A. G., REIFF R. H. Erythrokinetics in pernicious anemia. Blood. 1956 Sep;11(9):807–820. [PubMed] [Google Scholar]
  2. DINNING J. S., ALLEN B. K., YOUNG R. S., DAY P. L. The role of vitamin B12 in thymine biosynthesis by Lactobacillus leichmannii. J Biol Chem. 1958 Sep;233(3):674–676. [PubMed] [Google Scholar]
  3. DOWNING M., SCHWEIGERT B. S. Rôle of vitamin B12 in nucleic acid metabolism. IV. Metabolism of C14-labeled thymidine by Lactobacillus leichmannii. J Biol Chem. 1956 Jun;220(2):521–526. [PubMed] [Google Scholar]
  4. GLAZER H. S., MUELLER J. F., JARROLD T., SAKURAI K., WILL J. J., VILTER R. W. The effect of vitamin B12 and folic acid on nucleic acid composition of the bone marrow of patients with megaloblastic anemia. J Lab Clin Med. 1954 Jun;43(6):905–913. [PubMed] [Google Scholar]
  5. HUGULEY C. M., Jr, BAIN J. A., RIVERS S. L., SCOGGINS R. B. Refractory megaloblastic anemia associated with excretion of orotic acid. Blood. 1959 Jun;14(6):615–634. [PubMed] [Google Scholar]
  6. JOHNSON B. C. Studies on the mechanism of action of vitamin B12 in animal nutrition. Am J Clin Nutr. 1958 Jan-Feb;6(1):34–49. doi: 10.1093/ajcn/6.1.34. [DOI] [PubMed] [Google Scholar]
  7. LIEBERMAN I., KORNBERG A. Enzymic synthesis and breakdown of a pyrimidine, orotic acid. I. Dihydro-orotic dehydrogenase. Biochim Biophys Acta. 1953 Sep-Oct;12(1-2):223–234. doi: 10.1016/0006-3002(53)90141-3. [DOI] [PubMed] [Google Scholar]
  8. LOWENSTEIN J. M., COHEN P. P. Studies on the mechanism of carbamylaspartic acid synthesis. J Biol Chem. 1955 Apr;213(2):689–696. [PubMed] [Google Scholar]
  9. PARDEE A. B., YATES R. A. Control of pyrimidine biosynthesis in Escherichia coli by a feed-back mechanism. J Biol Chem. 1956 Aug;221(2):757–770. [PubMed] [Google Scholar]
  10. RUNDLES R. W., BREWER S. S., Jr Hematologic responses in pernicious anemia to orotic acid. Blood. 1958 Feb;13(2):99–115. [PubMed] [Google Scholar]
  11. SMITH L. H., Jr, BAKER F. A. Pyrimidine metabolism in man. I. The biosynthesis of orotic acid. J Clin Invest. 1959 May;38(5):798–809. doi: 10.1172/JCI103862. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. THOMAS E. D., LOCHTE H. L., Jr Studies on the biochemical defect of pernicious anemia. I. In vitro observations on oxygen consumption, heme synthesis and deoxyribonucleic acid synthesis by pernicious anemia bone marrow. J Clin Invest. 1958 Feb;37(2):166–171. doi: 10.1172/JCI103595. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. VILTER R. W., HORRIGAN D., MUELLER J. F., JARROLD T., VILTER C. F., HAWKINS V., SEAMAN A. Studies on the relationships of vitamin B12, folic acid, thymine, uracil and methyl group donors in persons with pernicious anemia and related megaloblastic anemias. Blood. 1950 Aug;5(8):695–717. [PubMed] [Google Scholar]
  14. WYNGAARDEN J. B., ASHTON D. M. The regulation of activity of phosphoribosyl-pyrophosphate amidotransferase by purine ribonacleotides: a potential feedback control of purine biosyntoesis. J Biol Chem. 1959 Jun;234(6):1492–1496. [PubMed] [Google Scholar]
  15. YATES R. A., PARDEE A. B. Control by uracil of formation of enzymes required for orotate synthesis. J Biol Chem. 1957 Aug;227(2):677–692. [PubMed] [Google Scholar]

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