APPLIED BIOLOGICAL SCIENCES Correction for “Lipid-like materials for low-dose, in vivo gene silencing,” by Kevin T. Love, Kerry P. Mahon, Christopher G. Levins, Kathryn A. Whitehead, William Querbes, J. Robert Dorkin, June Qin, William Cantley, Liu Liang Qin, Timothy Racie, Maria Frank-Kamenetsky, Ka Ning Yip, Rene Alvarez, Dinah W. Y. Sah, Antonin de Fougerolles, Kevin Fitzgerald, Victor Koteliansky, Akin Akinc, Robert Langer, and Daniel G. Anderson, which appeared in issue 5, February 2, 2010, of Proc Natl Acad Sci USA (107:1864–1869; first published January 11, 2010; 10.1073/pnas.0910603106).
The authors note that due to a printer’s error, the caption for Fig. 2 did not appear in full. The caption “(B) Luciferase” should instead appear as “(B) Luciferase silencing at low doses of siRNA (s.d., n = 4).” The figure and its corrected legend appear below.
Fig. 2.
In vitro screening of lipidoid library. Lipidoids were screened in luciferase-expressing Hela-derived cell line. (A) Antifirefly luciferase siRNA was complexed with lipidoids and incubated with cells in presence of growth media. Relative firefly luciferase expression determined by comparison of detected protein levels in treated groups vs. untreated control. (B) Luciferase silencing at low doses of siRNA (s.d., n = 4).