Skip to main content
NCBI home page
The Journal of Clinical Investigation logoLink to The Journal of Clinical Investigation
. 1961 Jan;40(1):130–139. doi: 10.1172/JCI104226

EFFECTS OF PRIMAQUINE AND OTHER RELATED COMPOUNDS ON THE RED BLOOD CELL MEMBRANE. I. NA+ AND K+ PERMEABILITY IN NORMAL HUMAN CELLS*

R Weed 1,2,†, J Eber 1,2, A Rothstein 1,2
PMCID: PMC290697  PMID: 13783698

Full text

PDF
130

Images in this article

134Image
on p.134

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ALTMAN K. I., IZZO M. J., SWISHER S. N., YOUNG L. E. Studies on spontaneous in vitro autohemolysis in hemolytic disorders. Blood. 1956 Nov;11(11):977–997. [PubMed] [Google Scholar]
  2. ALVING A. S., CARSON P. E., FLANAGAN C. L., ICKES C. E. Enzymatic deficiency in primaquine-sensitive erythrocytes. Science. 1956 Sep 14;124(3220):484–485. doi: 10.1126/science.124.3220.484-a. [DOI] [PubMed] [Google Scholar]
  3. BENESCH R. E., BENESCH R. Relation between erythrocyte integrity and sulfhydryl groups. Arch Biochem Biophys. 1954 Jan;48(1):38–42. doi: 10.1016/0003-9861(54)90302-1. [DOI] [PubMed] [Google Scholar]
  4. BEUTLER E., DERN R. J., ALVING A. S. The hemolytic effect of primaquine. III. A study of primaquine-sensitive erythrocytes. J Lab Clin Med. 1954 Aug;44(2):177–184. [PubMed] [Google Scholar]
  5. BEUTLER E., DERN R. J., FLANAGAN C. L., ALVING A. S. The hemolytic effect of primaquine. VII. Biochemical studies of drug-sensitive erythrocytes. J Lab Clin Med. 1955 Feb;45(2):286–295. [PubMed] [Google Scholar]
  6. BEUTLER E. The glutathione instability of drug-sensitive red cells; a new method for the in vitro detection of drug sensitivity. J Lab Clin Med. 1957 Jan;49(1):84–95. [PubMed] [Google Scholar]
  7. BEUTLER E. The hemolytic effect of primaquine and related compounds: a review. Blood. 1959 Feb;14(2):103–139. [PubMed] [Google Scholar]
  8. DERN R. J., BEUTLER E., ALVING A. S. The hemolytic effect of primaquine. II. The natural course of the hemolytic anemia and the mechanism of its self-limited character. J Lab Clin Med. 1954 Aug;44(2):171–176. [PubMed] [Google Scholar]
  9. DERN R. J., BEUTLER E., ALVING A. S. The hemolytic effect of primaquine. V. Primaquine sensitivity as a manifestation of a multiple drug sensitivity. J Lab Clin Med. 1955 Jan;45(1):30–39. [PubMed] [Google Scholar]
  10. DERN R. J., WEINSTEIN I. M., LEROY G. V., TALMAGE D. W., ALVING A. S. The hemolytic effect of primaquine. I. The localization of the drug-induced hemolytic defect in primaquine-sensitive individuals. J Lab Clin Med. 1954 Feb;43(2):303–309. [PubMed] [Google Scholar]
  11. ECKEL R. E. Potassium exchange in human erythrocytes. I. General aspects of the fluoride effect. J Cell Physiol. 1958 Feb;51(1):81–108. doi: 10.1002/jcp.1030510106. [DOI] [PubMed] [Google Scholar]
  12. ECKEL R. E. Potassium exchange in human erythrocytes. II. The division of cell potassium into two fractions during incubation with 0.025 M NaF. J Cell Physiol. 1958 Feb;51(1):109–132. doi: 10.1002/jcp.1030510107. [DOI] [PubMed] [Google Scholar]
  13. FEGLER G. Relationship between reduced glutathione content and spontaneous haemolysis in shed blood. Nature. 1952 Oct 11;170(4328):624–625. doi: 10.1038/170624a0. [DOI] [PubMed] [Google Scholar]
  14. GRUNERT R. R., PHILLIPS P. H. A modification of the nitroprusside method of analysis for glutathione. Arch Biochem. 1951 Feb;30(2):217–225. [PubMed] [Google Scholar]
  15. HEEDMAN P. A. Hemolysis of individual red blood cells; an interferometer microscopic investigation. Exp Cell Res. 1958 Feb;14(1):9–22. doi: 10.1016/0014-4827(58)90209-x. [DOI] [PubMed] [Google Scholar]
  16. HOUCHIN D. N., MUNN J. I., PARNELL B. L. A method for the measurement of red cell dimensions and calculation of mean corpuscular volume and surface area. Blood. 1958 Dec;13(12):1185–1191. [PubMed] [Google Scholar]
  17. PASSOW H., ROTHSTEIN A., LOEWENSTEIN B. An all-ornone response in thh release of potassium by yeast cells with methylene blue and other basic redox dyes. J Gen Physiol. 1959 Sep;43:97–107. doi: 10.1085/jgp.43.1.97. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. PASSOW H., TILLMAN K. Untersuchungen über den Kaliumverlust bleivergifteter Menschenerythrocyten. Pflugers Arch. 1955;262(1):23–36. doi: 10.1007/BF00369731. [DOI] [PubMed] [Google Scholar]
  19. PONDER E., COX R. T. Hemolysis considered as a progressive reaction in a heterogeneous system. J Gen Physiol. 1952 Mar;35(4):595–603. doi: 10.1085/jgp.35.4.595. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. Parpart A. K., Lorenz P. B., Parpart E. R., Gregg J. R., Chase A. M. THE OSMOTIC RESISTANCE (FRAGILITY) OF HUMAN RED CELLS. J Clin Invest. 1947 Jul;26(4):636–640. doi: 10.1172/JCI101847. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. ROTHSTEIN A. Cell membrane as site of action of heavy metals. Fed Proc. 1959 Dec;18:1026–1038. [PubMed] [Google Scholar]
  22. SHEETS R. F., HAMILTON H. E., DEGOWIN E. L. Hemolysis of human erythrocytes by a sulfhydryl inhibitor, p-chloromercuribenzoic acid. Proc Soc Exp Biol Med. 1956 Mar;91(3):423–427. doi: 10.3181/00379727-91-22283. [DOI] [PubMed] [Google Scholar]
  23. VINCENT P. C. The effects of heavy metal ions on the human erythrocyte. II. The effects of lead and mercury. Aust J Exp Biol Med Sci. 1958 Dec;36(6):589–601. doi: 10.1038/icb.1958.64. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Clinical Investigation are provided here courtesy of American Society for Clinical Investigation

RESOURCES