Skip to main content
PMC home page
The Journal of Clinical Investigation logoLink to The Journal of Clinical Investigation
. 1961 Feb;40(2):261–272. doi: 10.1172/JCI104252

STUDIES OF ANTERIOR PITUITARY TISSUE IN VITRO: EFFECTS OF INSULIN AND EXPERIMENTAL DIABETES MELLITUS UPON CARBOHYDRATE METABOLISM*

Charles J Goodner 1,2,†, Norbert Freinkel 1,2
PMCID: PMC290718  PMID: 13707057

Full text

PDF
261

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BRADY R. O., GURIN S. Biosynthesis of labeled fatty acids and cholesterol in experimental diabetes. J Biol Chem. 1950 Dec;187(2):589–596. [PubMed] [Google Scholar]
  2. CHAIN E. B. Recent studies on carbohydrate metabolism. Br Med J. 1959 Oct 17;2(5154):709–719. doi: 10.1136/bmj.2.5154.709. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. DE BODO R. C., ALTSZULER N. Insulin hypersensitivity and physiological insulin antagonists. Physiol Rev. 1958 Jul;38(3):389–445. doi: 10.1152/physrev.1958.38.3.389. [DOI] [PubMed] [Google Scholar]
  4. ELLIS S. Pituitary proteinase I: Purification and action on growth hormone and prolactin. J Biol Chem. 1960 Jun;235:1694–1699. [PubMed] [Google Scholar]
  5. ENGEL F. L., HEWSON K. Fatty acid and ketone metabolism during hemorrhage and shock in the rat. Proc Soc Exp Biol Med. 1953 Jul;83(3):608–611. doi: 10.3181/00379727-83-20434. [DOI] [PubMed] [Google Scholar]
  6. FOLCH J., LEES M., SLOANE STANLEY G. H. A simple method for the isolation and purification of total lipides from animal tissues. J Biol Chem. 1957 May;226(1):497–509. [PubMed] [Google Scholar]
  7. FREINKEL N., INGBAR S. H. The effects of the arylsulfonylureas on the respiratory activity and glucose metabolism of isolated rabbit kidney cortex. Endocrinology. 1959 Jun;64(6):1002–1009. doi: 10.1210/endo-64-6-1002. [DOI] [PubMed] [Google Scholar]
  8. GREGORY R. L., DRAGER G. A., TSAI S. Y., MAY L. G. The effect of diabetes of pancreatectomy on the pituitary cytology of dogs. Endocrinology. 1956 Jan;58(1):79–82. doi: 10.1210/endo-58-1-79. [DOI] [PubMed] [Google Scholar]
  9. HAFT D. E., MILLER L. L. Alloxan diabetes and demonstrated direct action of insulin on metabolism of isolated perfused rat liver. Am J Physiol. 1958 Jan;192(1):33–42. doi: 10.1152/ajplegacy.1957.192.1.33. [DOI] [PubMed] [Google Scholar]
  10. HAYNES R. C., Jr, BERTHET L. Studies on the mechanism of action of the adrenocorticotropic hormone. J Biol Chem. 1957 Mar;225(1):115–124. [PubMed] [Google Scholar]
  11. HUGGETT A. S., NIXON D. A. Use of glucose oxidase, peroxidase, and O-dianisidine in determination of blood and urinary glucose. Lancet. 1957 Aug 24;273(6991):368–370. doi: 10.1016/s0140-6736(57)92595-3. [DOI] [PubMed] [Google Scholar]
  12. LEVEY H. A., ROBERTS S. Influence of thyroid function on the metabolism of the anterior pituitary gland. Am J Physiol. 1957 Apr;189(1):86–90. doi: 10.1152/ajplegacy.1957.189.1.86. [DOI] [PubMed] [Google Scholar]
  13. MADISON L. L., COMBES B., ADAMS R., STRICKLAND W. The physiological significance of the secretion of endogenous insulin into the portal circulation. III. Evidence for a direct immediate effect of insulin on the balance of glucose across the liver. J Clin Invest. 1960 Mar;39:507–522. doi: 10.1172/JCI104065. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. NARAHARA H. T., WILLIAMS R. H. Degradation of insulin- I 131 by an extract of anterior pituitary gland. Am J Physiol. 1958 Jun;193(3):476–478. doi: 10.1152/ajplegacy.1958.193.3.476. [DOI] [PubMed] [Google Scholar]
  15. NARAHARA H. T., WILLIAMS R. H. Effect of protein added in vitro upon insulin degradation and glucose uptake by muscle. J Biol Chem. 1958 Nov;233(5):1034–1040. [PubMed] [Google Scholar]
  16. PERON F. G., KORITZ S. B. On the exogenous requirements for the action of ACTH in vitro on rat adrenal glands. J Biol Chem. 1958 Jul;233(1):256–259. [PubMed] [Google Scholar]
  17. PIAZZA E. U., GOODNER C. J., FREINKEL N. A re-evaluation of in vitro methods for insulin bio-assay. Diabetes. 1959 Nov-Dec;8:459–465. doi: 10.2337/diab.8.6.459. [DOI] [PubMed] [Google Scholar]
  18. RAFAELSEN O. J. Action of insulin on isolated rat spinal cord. Lancet. 1958 Nov 1;2(7053):941–943. doi: 10.1016/s0140-6736(58)90432-x. [DOI] [PubMed] [Google Scholar]
  19. RENOLD A. E., ASHMORE J., HASTINGS A. B. Regulation of carbohydrate metabolism in isolated tissues. Vitam Horm. 1956;14:139–185. doi: 10.1016/s0083-6729(08)60300-3. [DOI] [PubMed] [Google Scholar]
  20. RENOLD A. E., HASTINGS A. B., NESBETT F. B., ASHMORE J. Studies on carbohydrate metabolism in rat liver slices. IV. Biochemical sequence of events after insulin administration. J Biol Chem. 1955 Mar;213(1):135–146. [PubMed] [Google Scholar]
  21. RENOLD A. E., MARTIN D. B., DAGENAIS Y. M., STEINKE J., NICKERSON R. J., SHEPS M. C. Measurement of small quantities of insulin-like activity using rat adipose tissue. I. A proposed procedure. J Clin Invest. 1960 Sep;39:1487–1498. doi: 10.1172/JCI104168. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. ROBERTS S., KELLER M. R. Respiration and glycolysis in the hypophysis and hypothalamus of the rat. Arch Biochem Biophys. 1953 May;44(1):9–14. doi: 10.1016/0003-9861(53)90003-4. [DOI] [PubMed] [Google Scholar]
  23. SCOW R. O. Total pancreatectomy in the rat: operation, effects, and postoperative care. Endocrinology. 1957 Mar;60(3):359–367. doi: 10.1210/endo-60-3-359. [DOI] [PubMed] [Google Scholar]
  24. SCOW R. O., WAGNER E. M., CARDEZA A. Effect of hypophysectomy on the insulin requirement and response to fasting of totally pancreatectomized rats. Endocrinology. 1957 Oct;61(4):380–391. doi: 10.1210/endo-61-4-380. [DOI] [PubMed] [Google Scholar]
  25. WILLIAMS W. R., HILL R., CHAIKOFF I. L. Portal venous injection of insulin in the diabetic rat: time of induction of changes in hepatic lipogenesis, cholesterogenesis, and glycogenesis. J Lipid Res. 1960 Apr;1:236–240. [PubMed] [Google Scholar]
  26. WILSON J. D., SIPERSTEIN M. D. Studies on the relationship between glucose oxidation and intermediary metabolism. III. The influence of pyridine nucleotides on protein synthesis. J Clin Invest. 1959 Feb;38(2):317–324. doi: 10.1172/JCI103804. [DOI] [PMC free article] [PubMed] [Google Scholar]
  27. WINEGRAD A. I., RENOLD A. E. Studies on rat adipose tissue in vitro. I. Effects of insulin on the metabolism of glucose, pyruvate, and acetate. J Biol Chem. 1958 Aug;233(2):267–272. [PubMed] [Google Scholar]

Articles from Journal of Clinical Investigation are provided here courtesy of American Society for Clinical Investigation

RESOURCES