TABLE 2.
Genotype | Response (%) | na |
---|---|---|
Wild typeb | 82.5 | 80 |
pkd-2c | 54.2* | 96 |
tba-6 | 72.9* | 96 |
tba-9 | 60.0* | 85 |
tbb-4 | 59.3* | 86 |
tba-6; tbb-4 | 50.0* | 42 |
tba-6; tba-9 | 54.8* | 42 |
tba-9 tbb-4 | 35.0* | 40 |
tba-6; pkd-2 | 65.4* | 107 |
pkd-2; tba-9 | 26.4*,** | 91 |
pkd-2; tbb-4 | 57.7* | 97 |
tba-6; tba-9 tbb-4 | 44.7* | 76 |
tba-6; pkd-2; tba-9 tbb-4 | 32.6* | 46 |
*P < 0.01 vs. him-5 (Fisher's exact test); **P < 0.0001 vs. tba-9 or pkd-2 (Fisher's exact test).
n is the number of observations (see materials and methods).
him-5(e1490) is in the background of all strains and is used as the wild-type control.
The pkd-2 null allele sy606 was used for these experiments.