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. 2010 Jul;12(7):590–598. doi: 10.1593/neo.10726

Figure 4.

Figure 4

ERG protein expression in high-grade prostatic intraepithelial neoplasia (HG PIN) adjacent to ERG-expressing cancer. (A) H&E stain demonstrates small prostatic cancerous glands on the left and a larger atypical gland on the right with a subset of epithelial cells with neoplastic features consistent with HG PIN. (B) ERG protein expression by IHC demonstrates strong expression in both cancer and HG PIN. The arrowheads indicate a discrete demarcation between HG PIN and histologically benign luminal epithelial cells (40x).