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. 1961 Jul;40(7):1263–1279. doi: 10.1172/JCI104356

THE METABOLISM OF VARIOUSLY C14-LABELED GLUCOSE IN MAN AND AN ESTIMATION OF THE EXTENT OF GLUCOSE METABOLISM BY THE HEXOSE MONOPHOSPHATE PATHWAY

Stanton Segal 1, Mones Berman 1, Alberta Blair 1
PMCID: PMC290839  PMID: 13749668

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ABRAHAM S., CHAIKOFF I. L. Glycolytic pathways and lipogenesis in mammary glands of lactating and nonlactating normal rats. J Biol Chem. 1959 Sep;234:2246–2253. [PubMed] [Google Scholar]
  2. ABRAHAM S., HIRSCH P. F., CHAIKOFF I. L. The quantitative significance of glycolysis and non-glycolysis in glucose utilization by rat mammary gland. J Biol Chem. 1954 Nov;211(1):31–38. [PubMed] [Google Scholar]
  3. AMATUZIO D. S., STUTZMAN F. L., VANDERBILT M. J., NESBITT S. Interpretation of the rapid intravenous glucose tolerance test in normal individuals and in mild diabetes mellitus. J Clin Invest. 1953 May;32(5):428–435. doi: 10.1172/JCI102755. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. ARNSTEIN H. R., KEGLEVIC D. A comparison of alanine and glucose as precursors of serine and glycine. Biochem J. 1956 Feb;62(2):199–205. doi: 10.1042/bj0620199. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. BAKER N., SHIPLEY R. A., CLARK R. E., INCEFY G. E. C14 studies in carbohydrate metabolism: glucose pool size and rate of turnover in the normal rat. Am J Physiol. 1959 Feb;196(2):245–252. doi: 10.1152/ajplegacy.1959.196.2.245. [DOI] [PubMed] [Google Scholar]
  6. BAKER N., SHREEVE W. W., SHIPLEY R. A., INCEFY G. E., MILLER M. C14 studies in carbohydrate metabolism. I. The oxidation of glucose in normal human subjects. J Biol Chem. 1954 Dec;211(2):575–592. [PubMed] [Google Scholar]
  7. BECK W. S. Occurrence and control of the phosphogluconate oxidation pathway in normal and leukemic leukocytes. J Biol Chem. 1958 May;232(1):271–283. [PubMed] [Google Scholar]
  8. BERSON S. A., WEISENFELD S., PASCULLO M. Utilization of glucose in normal and diabetic rabbits; effects of insulin, glucagon and glucose. Diabetes. 1959 Mar-Apr;8(2):116–127. doi: 10.2337/diab.8.2.116. [DOI] [PubMed] [Google Scholar]
  9. BLAIR A., SEGAL S. The isolation of blood glucose as potassium gluconate. J Lab Clin Med. 1960 Jun;55:959–964. [PubMed] [Google Scholar]
  10. BLOOM B. Fraction of glucose catabolized via the Embden-Meyerhof pathway: alloxan-diabetic and fasted rats. J Biol Chem. 1955 Aug;215(2):467–472. [PubMed] [Google Scholar]
  11. BLOOM B., STETTEN M. R., STETTEN D., Jr Evaluation of catabolic pathways of glucose in mammalian systems. J Biol Chem. 1953 Oct;204(2):681–694. [PubMed] [Google Scholar]
  12. BRIN M., YONEMOTO R. H. Stimulation of the glucose oxidative pathway in human erythrocytes by methylene blue. J Biol Chem. 1958 Jan;230(1):307–317. [PubMed] [Google Scholar]
  13. COXON R. V., ROBINSON R. J. The transport of radioactive carbon dioxide in the blood stream of the dog after administration of radioactive bicarbonate. J Physiol. 1959 Oct;147:469–486. doi: 10.1113/jphysiol.1959.sp006257. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. EISENBERG F., Jr, DAYTON P. G., BURNS J. J. Studies on the glucuronic acid pathway of glucose metabolism. J Biol Chem. 1959 Feb;234(2):250–253. [PubMed] [Google Scholar]
  15. ENTNER N., DOUDOROFF M. Glucose and gluconic acid oxidation of Pseudomonas saccharophila. J Biol Chem. 1952 May;196(2):853–862. [PubMed] [Google Scholar]
  16. FREDRICKSON D. S., ONO K. An improved technique for assay of C14O2 in expired air using the liquid scintillation counter. J Lab Clin Med. 1958 Jan;51(1):147–151. [PubMed] [Google Scholar]
  17. FROESCH E. R., RENOLD A. E. Specific enzymatic determination of glucose in blood and urine using glucose oxidase. Diabetes. 1956 Jan-Feb;5(1):1–6. doi: 10.2337/diab.5.1.1. [DOI] [PubMed] [Google Scholar]
  18. HIATT H. H. Studies of ribose metabolism. III. The pathway of ribose carbon conversion to glucose in man. J Clin Invest. 1958 May;37(5):651–654. doi: 10.1172/JCI103649. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. HORECKER B. L., HIATT H. H. Pathways of carbohydrate metabolism in normal and neoplastic cells. N Engl J Med. 1958 Jan 23;258(4):177–contd. doi: 10.1056/NEJM195801232580406. [DOI] [PubMed] [Google Scholar]
  20. HORECKER B. L., MEHLER A. H. Carbohydrate metabolism. Annu Rev Biochem. 1955;24:207–274. doi: 10.1146/annurev.bi.24.070155.001231. [DOI] [PubMed] [Google Scholar]
  21. JACOBS G., REICHARD G., GOODMAN E. H., Jr, FRIEDMANN B., WEINHOUSE S. Action of insulin and tolbutamide on blood glucose entry and removal. Diabetes. 1958 Sep-Oct;7(5):358–364. doi: 10.2337/diab.7.5.358. [DOI] [PubMed] [Google Scholar]
  22. JEANRENAUD B., RENOLD A. E. Studies on rat adipose tissue in vitro. IV. Metabolic patterns produced in rat adipose tissue by varying insulin and glucose concentrations independently from each other. J Biol Chem. 1959 Dec;234:3082–3087. [PubMed] [Google Scholar]
  23. KATZ J., ABRAHAM S., HILL R., CHAIKOFF I. L. The occurrence and mechanism of the hexose monophosphate shunt in rat liver slices. J Biol Chem. 1955 Jun;214(2):853–868. [PubMed] [Google Scholar]
  24. KATZ J., WOOD H. G. The use of glucose-C14 for the evaluation of the pathways of glucose metabolism. J Biol Chem. 1960 Aug;235:2165–2177. [PubMed] [Google Scholar]
  25. KIPNIS D. M., HELMREICH E., CORI C. F. Studies of tissue permeability. IV. The distribution of glucose between plasma and muscle. J Biol Chem. 1959 Jan;234(1):165–170. [PubMed] [Google Scholar]
  26. KORKES S. Carbohydrate metabolism. Annu Rev Biochem. 1956;25:685–734. doi: 10.1146/annurev.bi.25.070156.003345. [DOI] [PubMed] [Google Scholar]
  27. LEONARDS J. R., LANDAU B. R. A study of the equivalence of metabolic patterns in rat adipose tissue: insulin versus glucose concentration. Arch Biochem Biophys. 1960 Dec;91:194–200. doi: 10.1016/0003-9861(60)90489-6. [DOI] [PubMed] [Google Scholar]
  28. MUNTZ J. A., MURPHY J. R. The metabolism of variously labeled glucose in rat liver in vivo. J Biol Chem. 1957 Feb;224(2):971–985. [PubMed] [Google Scholar]
  29. MURPHY J. R. Erythrocyte metabolism. II. Glucose metabolism and pathways. J Lab Clin Med. 1960 Feb;55:286–302. [PubMed] [Google Scholar]
  30. MURPHY J. R., MUNTZ J. A. The metabolism of glucose in the perfused rat liver. J Biol Chem. 1957 Feb;224(2):987–997. [PubMed] [Google Scholar]
  31. SBARRA A. J., KARNOVSKY M. L. The biochemical basis of phagocytosis. I. Metabolic changes during the ingestion of particles by polymorphonuclear leukocytes. J Biol Chem. 1959 Jun;234(6):1355–1362. [PubMed] [Google Scholar]
  32. SEGAL S., FOLEY J. The metabolism of D-ribose in man. J Clin Invest. 1958 May;37(5):719–735. doi: 10.1172/JCI103658. [DOI] [PMC free article] [PubMed] [Google Scholar]
  33. SHIPLEY R. A., BAKER N., INCEFY G. E., CLARK R. E. C14 studies in carbohydrate metabolism. IV. Characteristics of bicarbonate pool system in the rat. Am J Physiol. 1959 Jul;197(1):41–46. doi: 10.1152/ajplegacy.1959.197.1.41. [DOI] [PubMed] [Google Scholar]
  34. SHREEVE W. W., BAKER N., MILLER M., SHIPLEY R. A., INCEFY G. E., CRAIG J. W. C14 studies in carbohydrate metabolism. II. The oxidation of glucose in diabetic human subjects. Metabolism. 1956 Jan;5(1):22–34. [PubMed] [Google Scholar]
  35. SHREEVE W. W., HENNES A. R., SCHWARTZ R. Production of C14O2 from 1- and 2-C14-acetate by human subjects in various metabolic states. Metabolism. 1959 Sep;8:741–756. [PubMed] [Google Scholar]
  36. STEELE R., ALTSZULER N., WALL J. S., DUNN A., DE BODO R. C. Influence of adrenalectomy on glucose turnover and conversion to CO2: studies with C14 glucose in the dog. Am J Physiol. 1959 Feb;196(2):221–230. doi: 10.1152/ajplegacy.1959.196.2.221. [DOI] [PubMed] [Google Scholar]
  37. STEELE R., WALL J. S., DE BODO R. C., ALTSZULER N. Measurement of size and turnover rate of body glucose pool by the isotope dilution method. Am J Physiol. 1956 Sep;187(1):15–24. doi: 10.1152/ajplegacy.1956.187.1.15. [DOI] [PubMed] [Google Scholar]
  38. STETTEN D., Jr, STETTEN M. R. Glycogen metabolism. Physiol Rev. 1960 Jul;40:505–537. doi: 10.1152/physrev.1960.40.3.505. [DOI] [PubMed] [Google Scholar]
  39. STETTEN D., Jr, WELT I. D., INGLE D. J., MORLEY E. H. Rates of glucose production and oxidation in normal and diabetic rats. J Biol Chem. 1951 Oct;192(2):817–830. [PubMed] [Google Scholar]
  40. VAN SLYKE D. D., PLAZIN J., WEISIGER J. R. Reagents for the Van Slyke-Folch wet carbon combustion. J Biol Chem. 1951 Jul;191(1):299–304. [PubMed] [Google Scholar]
  41. WOOD H. G. Significance of alternate pathways in the metabolism of glucose. Physiol Rev. 1955 Oct;35(4):841–859. doi: 10.1152/physrev.1955.35.4.841. [DOI] [PubMed] [Google Scholar]
  42. WYNGAARDEN J. B., SEGAL S., FOLEY J. B. Physiological disposition and metabolic fate of infused pentoses in man. J Clin Invest. 1957 Oct;36(10):1395–1407. doi: 10.1172/JCI103539. [DOI] [PMC free article] [PubMed] [Google Scholar]

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