Skip to main content
NCBI home page
The Journal of Clinical Investigation logoLink to The Journal of Clinical Investigation
. 1961 Nov;40(11):1935–1951. doi: 10.1172/JCI104419

PREPARATION AND BIOLOGICAL PROPERTIES OF A CHEMICALLY MODIFIED ESCHERICHIA COLI ENDOTOXIN OF HIGH IMMUNOGENIC POTENCY AND LOW TOXICITY

Hans Noll 1,2,*, Abraham I Braude 1,2,†
PMCID: PMC290896  PMID: 14480251

Full text

PDF
1935

Images in this article

1937Image
on p.1937

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BRAUDE A. I., CAREY F. J., SUTHERLAND D., ZALESKY M. Studies with radioactive endotoxin. I. The use of Cr51 to label endotoxin of Escherichia coli. J Clin Invest. 1955 Jun;34(6):850–857. doi: 10.1172/JCI103140. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. BRAUDE A. I., McCONNELL J., DOUGLAS H. Fever from pathogenic fungi. J Clin Invest. 1960 Aug;39:1266–1276. doi: 10.1172/JCI104142. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. BRAUDE A. I. Mechanism of action of a toxic bacterial antigen. Trans Am Acad Ophthalmol Otolaryngol. 1959 Sep-Oct;63:634–641. [PubMed] [Google Scholar]
  4. BRAUDE A. I., SHAPIRO A. P., SIEMIENSKI J. Hematogenous pyelonephritis in rats. I. Its pathogenesis when produced by a simple new method. J Clin Invest. 1955 Oct;34(10):1489–1497. doi: 10.1172/JCI103200. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. BRAUDE A. I., SHAPIRO A. P., SIEMIENSKI J. Hematogenous pyelonephritis in rats. III. Relationship of bacterial species to the pathogenesis of acute pyeionephritis. J Bacteriol. 1959 Mar;77(3):270–280. doi: 10.1128/jb.77.3.270-280.1959. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. FREEDMAN H. H. Further studies on passive transfer of tolerance to pyrogenicity of bacterial endotoxin. The febrile and leucopenic responses. J Exp Med. 1960 Oct 1;112:619–634. doi: 10.1084/jem.112.4.619. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. FROMME I., LUDERITZ O., NOWOTNY A., WESTPHAL O. Chemische Analyse des Lipopolysaccharids aus Salmonella abortus equi. Pharm Acta Helv. 1958 Aug-Oct;33(8-10):391–400. [PubMed] [Google Scholar]
  8. HALBERT S. P., SWICK L., SONN C. The use of precipitin analysis in agar for the study of human streptococcal infections. II. Ouchterlony and Oakley technics. J Exp Med. 1955 May 1;101(5):557–576. doi: 10.1084/jem.101.5.557. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. JERNE N. K. Immunological speculations. Annu Rev Microbiol. 1960;14:341–358. doi: 10.1146/annurev.mi.14.100160.002013. [DOI] [PubMed] [Google Scholar]
  10. JOHNSON R. B. An immunogenic antigen of low toxicity derived from Shigella sonnei. J Immunol. 1955 Apr;74(4):286–292. [PubMed] [Google Scholar]
  11. LANDY M. Enhancement of the immunogenicity of typhoid vaccine by retention of the V1 antigen. Am J Hyg. 1953 Sep;58(2):148–164. doi: 10.1093/oxfordjournals.aje.a119596. [DOI] [PubMed] [Google Scholar]
  12. LANDY M., JOHNSON A. G., WEBSTER M. E., SAGIN J. F. Studies on the O antigen of Salmonella typhosa. II. Immunological properties of the purified antigen. J Immunol. 1955 Jun;74(6):466–478. [PubMed] [Google Scholar]
  13. LUDERITZ O., WESTPHAL O., STAUB A. M., LE MINOR L. Preparation and immunological properties of an artificial antigen with colitose (3-deoxy-1-fucose) as the determinant group. Nature. 1960 Nov 12;188:556–558. doi: 10.1038/188556a0. [DOI] [PubMed] [Google Scholar]
  14. Morgan W. T., Partridge S. M. Studies in immunochemistry: The fractionation and nature of antigenic material isolated from Bact. dysenteriae (Shiga). Biochem J. 1940 Feb;34(2):169–191. doi: 10.1042/bj0340169. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. NETER E., WESTPHAL O., LUDERITZ O., GORZYNSKI E. A., EICHENBERGER E. Studies of enterobacterial lipopolysaccharides; effects of heat and chemicals on erythrocyte-modifying, antigenic, toxic and pyrogenic properties. J Immunol. 1956 May;76(5):377–385. [PubMed] [Google Scholar]
  16. NOLL H., BLOCH H., ASSELINEAU J., LEDERER E. The chemical structure of the cord factor of Mycobacterium tuberculosis. Biochim Biophys Acta. 1956 May;20(2):299–309. doi: 10.1016/0006-3002(56)90289-x. [DOI] [PubMed] [Google Scholar]
  17. NOLL H., BLOCH H. Studies on the chemistry of the cord factor of Mycobacterium tuberculosis. J Biol Chem. 1955 May;214(1):251–265. [PubMed] [Google Scholar]
  18. NOLL H., JACKIM E. The chemistry of the native constituents of the acetone-soluble fat of Mycobacterium tuberculosis (Brevannes). I. Glycerides and phosphoglycolipides. J Biol Chem. 1958 Jun;232(2):903–917. [PubMed] [Google Scholar]
  19. NOLL H. The chemistry of some native constituents of the purified wax of Mycobacterium tuberculosis. J Biol Chem. 1957 Jan;224(1):149–164. [PubMed] [Google Scholar]
  20. NOLL H. The physiocochemical characterization of vitamin K homologues. 1. Identification by a novel method of quantitive infrared spectrophotometry. J Biol Chem. 1960 Aug;235:2207–2216. [PubMed] [Google Scholar]
  21. NOLL H., YOUNGNER J. S. Virus-lipid interactions. II. The mechanism of adsorption of lipophilic viruses to water-insoluble polar lipids. Virology. 1959 Jul;8(3):319–343. doi: 10.1016/0042-6822(59)90033-9. [DOI] [PubMed] [Google Scholar]
  22. ROSEN H. A modified ninhydrin colorimetric analysis for amino acids. Arch Biochem Biophys. 1957 Mar;67(1):10–15. doi: 10.1016/0003-9861(57)90241-2. [DOI] [PubMed] [Google Scholar]
  23. SNYDER F., STEPHENS N. A simplified spectrophotometric determination of ester groups in lipids. Biochim Biophys Acta. 1959 Jul;34:244–245. doi: 10.1016/0006-3002(59)90255-0. [DOI] [PubMed] [Google Scholar]
  24. STAUB A. M. [Chemical basis of the immunological specificity of antigens of Salmonella]. Ann Inst Pasteur (Paris) 1960 Jun;98:814–828. [PubMed] [Google Scholar]
  25. TAKEDA Y., KASAI N., ARAKI M., ODAKA T. Die Chemie des O-Antigens, seine Toxizität und Antigenität. Hoppe Seylers Z Physiol Chem. 1957;307(2-6):49–61. [PubMed] [Google Scholar]
  26. WEBSTER M. E., SAGIN J. F., LANDY M., JOHNSON A. G. Studies on the O antigen of Salmonella typhosa. I. Purification of the antigen. J Immunol. 1955 Jun;74(6):455–465. [PubMed] [Google Scholar]
  27. WESTPHAL O. [Recent research on the chemistry and biology of the endotoxins of gram-negative bacteria]. Ann Inst Pasteur (Paris) 1960 Jun;98:789–813. [PubMed] [Google Scholar]

Articles from Journal of Clinical Investigation are provided here courtesy of American Society for Clinical Investigation

RESOURCES