Table 7.

Studies of single-channel nocturnal oximetry performed at home

Author, Year, Country	Number of subjects	Name of Device	Reference Diagnostic Criteria	Oximeter scoring criteria	Sn (%)	Sp (%)	LR+	LR−
Williams et al,5 1991, USA	40 referred to sleep clinic	Biox 3700 IV*, Nelllcor N100†	AI > 10	ODI 4%	58	92	10.6	0.16
				Oximetry plus clinical score	85	92	7.2	0.46
Series et al,6 1993, Canada	240 sleep clinic patients with possible OSA	Biox IVa‡	AHI ≥ 10	Visual scoring	98	48	1.9	0.04
Gyulay et al,7 1993, Australia	98 with possible OSA	Biox 3700§	AHI ≥ 15	Clinical assessment	79	50	1.6	0.42
				ODI 4%	40	98	20.0	0.61
				ODI 3%	51	90	5.1	0.54
				ODI 2%	65	74	2.5	0.47
				CT < 90	93	51	1.9	0.14
				Visual inspection	72	88	6.0	0.32
Ryan et al,8 1995, UK	69 with possible OSA	Minolta Pulsox-7**	AHI ≥ 15	ODI 4% > 15	32	100		0.68
Olson et al,9 1999, Australia	793 with possible OSA	Biox 4700††	AHI ≥ 15	Delta Index (< 0.6)	88	40	1.5	0.29
				CT 90 ≥ 1%	75	46	1.4	0.54
			AHI ≥ 30	Delta Index (< 0.6)	93	34	1.4	0.21
				CT 90 ≥ 1%	84	44	1.5	0.36
Wiltshire et al,10 2001, England	100 with possible OSA	Biox 3740‡‡	ODI ≥ 10	ODI ≥ 10	41	100	–	0.59
			ODI ≥ 15	ODI ≥ 15	35	100	–	0.65

AHI, Apnea hypopnea Index; AI, Apnea Index; ODI 4%, 3%, 2%, oxygen desaturation index per hour to 4%, 3%, 2%; CT < 90, cumulative time below 90% saturation; Delta Index, the average of the absolute differences of oxygen saturation between successive intervals; Sn, sensitivity; Sp, specificity; LR+, positive likelihood ratio; LR−, negative likelihood ratio;

^*Ohmeda, Boulder, CO, USA;

^†Nellcor Inc, Hayward, CA, USA;

^‡Ohmeda, Boulder, CO, USA;

^§Ohmeda, Boulder, CO, USA;

^**Minolta, Diessenhofen, Switzerland;

^‡‡Ohmeda, Boulder, CO, USA;

^‡‡Ohmeda, Boulder, CO, USA