Table 2.
Mean Initial FACT-C Scores (standard deviation) and MANOVA test statistic, Wilks Lambda P-value.
| P-value1 | N2 | Physical well-being | Social/Family well-being | Emotional well-being | Functional well-being | Colorectal concerns | |
|---|---|---|---|---|---|---|---|
| Age | 0.005 | ||||||
| <=65 | 78 | 20.4 (6.1) | 22.4 (4.5) | 18.9 (4.9) | 18.9 (6.3) | 19.9 (4.9) | |
| >65 | 82 | 23.4 (4.3) | 22.7 (4.6) | 20.7 (3.1) | 19.9 (5.4) | 21.7 (4.4) | |
| Gender | 0.009 | ||||||
| Male | 89 | 22.2 (5.2) | 21.7 (5.0) | 20.0 (3.8) | 19.0 (5.8) | 21.2 (4.6) | |
| Female | 71 | 21.6 (5.7) | 23.7 (3.6) | 19.7 (4.7) | 20.0 (6.0) | 20.3 (4.9) | |
| Race/Ethnicity | 0.19 | ||||||
| White | 125 | 22.3 (5.1) | 22.6 (4.3) | 19.9 (3.9) | 19.4 (5.7) | 20.7 (4.6) | |
| Black | 8 | 20.8 (6.9) | 22.3 (4.2) | 21.0 (4.0) | 20.1 (5.0) | 20.0 (7.1) | |
| Hispanic | 11 | 21.1 (6.3) | 23.3 (4.9) | 20.1 (3.8) | 19.3 (7.2) | 23.5 (3.5) | |
| Asian/PI | 16 | 20.0 (7.1) | 22.3 (6.1) | 18.7 (6.7) | 19.1 (7.4) | 20.3 (5.0) | |
| AJCC stage | 0.0003 | ||||||
| I | 53 | 23.9 (4.0) | 21.8 (5.6) | 21.0 (3.8) | 20.8 (5.7) | 22.1 (3.7) | |
| II | 41 | 21.8 (5.7) | 23.3 (3.5) | 20.1 (4.8) | 19.5 (5.9) | 20.2 (4.9) | |
| III | 56 | 20.9 (5.6) | 23.0 (4.2) | 19.4 (3.8) | 18.3 (5.9) | 20.1 (5.1) | |
| IV | 10 | 17.8 (5.8) | 21.9 (3.1) | 15.0 (5.5) | 18.5 (5.8) | 20.9 (5.5) | |
| Tumor location | 0.51 | ||||||
| Upper | 37 | 21.3 (5.8) | 22.6 (5.3) | 19.6 (4.9) | 19.5 (6.2) | 20.6 (5.7) | |
| Middle | 53 | 21.6 (5.8) | 22.7 (3.7) | 19.7 (3.8) | 18.1 (6.6) | 20.1 (5.0) | |
| Lower | 36 | 20.0 (5.3) | 21.9 (4.6) | 19.6 (4.0) | 19.9 (8.2) | 20.7 (3.8) | |
| Unknown | 34 | 23.0 (4.7) | 23.3 (4.7) | 20.6 (4.3) | 20.9 (5.2) | 22.3 (3.9) | |
| Surgery | 0.96 | ||||||
| LAR3 | 110 | 22.1 (5.2) | 22.8 (4.6) | 20.0 (4.4) | 19.6 (6.0) | 20.9 (4.8) | |
| APR4 | 50 | 21.5 (6.0) | 22.1 (4.3) | 19.5 (3.8) | 19.1 (5.6) | 20.6 (4.6) | |
| Adjuvant Therapy | 0.004 | ||||||
| None | 62 | 24.0 (4.4) | 22.6 (4.8) | 20.9 (3.9) | 20.6 (5.9) | 21.8 (4.3) | |
| Both | 88 | 20.1 (5.7) | 22.6 (4.4) | 19.1 (4.2) | 18.3 (5.8) | 19.9 (5.0) | |
| Some5 | 10 | 24.9 (2.3) | 22.6 (4.1) | 20.1 (4.6) | 21.9 (4.9) | 23.4 (3.0) |
1
P-value for Wilks' Lambda test statistic of multivariate mean differences for the MANOVA. Significant p-values lead to post-hoc analysis (ANOVA and repeated measures)
2
Initial respondents include the 71 patients who completed only the initial survey and the 89 patients who completed both initial and follow-up surveys, for a total of 160.
3
LAR=low anterior resection
4
APR= abdominoperineal resection
5
Either chemotherapy or radiation therapy, but not both.