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. 1976 May;31(5):685–690. doi: 10.1128/aem.31.5.685-690.1976

Effect of substrate on metabolite production of Alternaria alternata.

R Burroughs, L M Seitz, D B Sauer, H E Mohr
PMCID: PMC291176  PMID: 945039

Abstract

Alternariol and alternariol monomethyl ether are commonly associated with weathered grain sorghum. Production of these metabolites and altenuene by isolates of Alternaria alternata was evaluated on various sterile grain substrates. At 35% moisture content and 25 C, metabolite yields were highest on rice, intermediate on sorghums, and lowest on wheat and yellow corn. Fourteen-to 21-day cultures on milled rice were best in terms of ease of metabolite recovery, even though yields were higher on 28-day cultures of rough and brown rice. Metabolite production was reduced when rice was supplemented with yeast extract or yeast extract plus Czapek-Dox broth.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Eugenio C. P., Christensen C. M., Mirocha C. J. Factors affecting production of the mycotoxin F-2 by Fusarium roseum. Phytopathology. 1970 Jul;(7):1055–1057. doi: 10.1094/phyto-60-1055. [DOI] [PubMed] [Google Scholar]
  2. Hesseltine C. W., Shotwell O. L., Ellis J. J., Stubblefield R. D. Aflatoxin formation by Aspergillus flavus. Bacteriol Rev. 1966 Dec;30(4):795–805. doi: 10.1128/br.30.4.795-805.1966. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Lindenfelser L. A., Ciegler A. Solid-substrate fermentor for ochratoxin A production. Appl Microbiol. 1975 Mar;29(3):323–327. doi: 10.1128/am.29.3.323-327.1975. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Marsh P. B., Simpson M. E., Trucksess M. W. Effects of trace metals on the production of aflatoxins by Aspergillus parasiticus. Appl Microbiol. 1975 Jul;30(1):52–57. doi: 10.1128/am.30.1.52-57.1975. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Meronuck R. A., Steele J. A., Mirocha C. J., Christensen C. M. Tenuazonic acid, a toxic produced by Alternaria alternata. Appl Microbiol. 1972 Mar;23(3):613–617. doi: 10.1128/am.23.3.613-617.1972. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Pero R. W., Posner H., Blois M., Harvan D., Spalding J. W. Toxicity of metabolites produced by the "Alternaria". Environ Health Perspect. 1973 Jun;4:87–94. doi: 10.1289/ehp.730487. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. RAISTRICK H., STICKINGS C. E., THOMAS R. Studies in the biochemistry of microorganisms. 90. Alternariol and alternariol monomethyl ether, metabolic products of Alternaria tenuis. Biochem J. 1953 Oct;55(3):421–433. doi: 10.1042/bj0550421. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. ROSETT T., SANKHALA R. H., STICKINGS C. E., TAYLOR M. E., THOMAS R. Studies in the biochemistry of micro-organisms. 103. Metabolites of Alternaria tenuis auct; culture filtrate products. Biochem J. 1957 Nov;67(3):390–400. doi: 10.1042/bj0670390. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Seitz L. M., Mohr H. E. Analysis of Alternaria metabolites by high-pressure liquid chromatography. Anal Biochem. 1976 Jan;70(1):224–230. doi: 10.1016/s0003-2697(76)80062-0. [DOI] [PubMed] [Google Scholar]
  10. Seitz L. M., Sauer D. B., Monr H. E., Burroughs R., Paukstelis J. V. Metabolites of Alternaria in grain sorghum. Compounds which could be mistaken for zearalenone and aflatoxin. J Agric Food Chem. 1975 Jan-Feb;23(1):1–4. doi: 10.1021/jf60197a015. [DOI] [PubMed] [Google Scholar]
  11. THOMAS R. Studies in the biosynthesis of fungal metabolites. 4. Alternariol monomethyl ether and its relation to other phenolic metabolites of Alternaria tenuis. Biochem J. 1961 Aug;80:234–240. doi: 10.1042/bj0800234. [DOI] [PMC free article] [PubMed] [Google Scholar]

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