Table 2.

Selected optimization of aziridination reaction.

Entry	Catalyst (mol %)	PhI=NTs (equiv)	Solvent	Temp.(°C)	Yield (%)[a]
1	Cu(acac)2 (10)	2	CH3CN	0 to rt	28
2	CuTc (20)	2	CH3CN	0 to rt	29–40
3	Cu(OTf)2 (20)	2	CH3CN	rt	trace
4	CuOTf (10)	2	DME	rt	0
5	CuOTf (30)	3	CH3CN	rt	16
6	CuOTf (10)	2	benzene	0 to rt	30
7	CuOTf (50)	2	benzene	rt	41
8	CuOTf (100)	2	benzene	rt	47
9	Cu(py)2Cl2 (100)	2	DCM	rt	<30
10	Catalyst 13 (50)	5	benzene[b]	0 to rt	52
11	Catalyst 14 (50)	5	benzene	0 to rt	51

^[a]Isolated yield.

^[b]Decomposition was observed when CH₃CN was used as solvent.