Table 2.
Qualitative scores in brain structures of 18 good and 15 poor outcome patients
| Structure | FLAIR qualitative score median (IQR, range) |
DWI qualitative score median (IQR, range) |
||||
|---|---|---|---|---|---|---|
| (maximum possible score) |
Good outcome (19 scans) |
Poor outcome (18 scans) |
p- value |
Good outcome (20 scans) |
Poor outcome (18 scans) |
p- value |
| Temporal lobe (8) | 0 (0-1, 0-2.5) | 3 (1-4, 0-4.5) | 0.001 | 0.25 (0-1, 0-2) | 3.5 (1.5-4, 0-5) | <0.001 |
| Gray Matter (4) | 0 (0-1, 0-2.5) | 3 (1-4, 0-4) | 0.001 | 0 (0-1, 0-2) | 3.5 (1.5-4, 0-4) | <0.001 |
| White Matter (4) | 0 (0-0, 0-0) | 0 (0-0, 0-0.5) | 0.578 | 0 (0-0, 0-0.5) | 0 (0-0, 0-1) | 0.965 |
| Occipital lobe (8) | 0 (0-1, 0-2.5) | 3.25 (2-4, 0-4.5) | <0.001 | 0 (0-1, 0-3) | 4 (3.5-4, 0-5) | <0.001 |
| Gray Matter (4) | 0 (0-1, 0-2.5) | 3.25 (2-4, 0-4) | <0.001 | 0 (0-1, 0-3) | 4 (3.5-4, 0-4) | <0.001 |
| White Matter (4) | 0 (0-0, 0-0) | 0 (0-0, 0-0) | 0.391 | 0 (0-0, 0-1.5) | 0 (0-0, 0-1) | 0.784 |
| Frontal lobe (8) | 0 (0-1, 0-2.5) | 3.25 (1-4.5, 0-5) | <0.001 | 0.5 (0-1.5, 0-2.5) | 3.75 (2-4, 0-5.5) | <0.001 |
| Gray Matter (4) | 0 (0-0.75, 0-2.5) | 3.25 (1-4.5, 0-4) | <0.001 | 0.5 (0-1.25, 0-2.5) | 3.75 (2-4, 0-4) | <0.001 |
| White Matter (4) | 0 (0-0, 0-0.5) | 0 (0-0.5, 0-1) | 0.142 | 0 (0-0, 0-0.5) | 0 (0-0, 0-1.5) | 0.965 |
| Parietal lobe (8) | 0 (0-1, 0-2.5) | 3.5 (2-4.5, 0-5) | <0.001 | 0.5 (0-1.75, 0-3) | 4 (2-4, 0-5.5) | <0.001 |
| Gray Matter (4) | 0 (0-0.75, 0-2.5) | 3.5 (1-4, 0-4) | <0.001 | 0.25 (0-1.5, 0-3) | 4 (2-4, 0-4) | <0.001 |
| White Matter (4) | 0 (0-0, 0-1) | 0 (0-0.5, 0-2) | 0.358 | 0 (0-0.5, 0-0.5) | 0 (0-0, 0-1.5) | 0.613 |
| Hippocampus (4) | 1 (0.5-2.25, 0-3.5) | 2.75 (2-4, 0-4) | 0.003 | 1.5 (0.5-2.5, 0-3.5) | 3 (1-4, 0-4) | 0.038 |
| Thalamus (4) | 1 (0-2, 0-3) | 3 (2.5-4, 0-4) | <0.001 | 1 (0.25-1.5, 0-3) | 2.25 (2-3, 0-4) | 0.002 |
| Caudate Nucleus (4) | 0.5 (0-1, 0-4) | 3.25 (2-4, 0-4) | <0.001 | 1 (0-1.75, 0-3.5) | 3.25 (2.5-3.5, 0-4) | <0.001 |
| Putamen (4) | 0 (0-1, 0-4) | 3.5 (1.5-4, 0-4) | <0.001 | 0.5 (0-1.25, 0-3.5 | 3 (2-3.5, 0-4) | 0.001 |
| Cerebellum (8) | 0 (0-0.25, 0-5) | 2.5 (0.5-4, 0-6.5) | <0.001 | 1.75 (0.5-2.25, 0-5) | 3.25 (2-4, 0-6) | 0.007 |
| Cortex (4) | 0 (0-0.25, 0-4) | 2.5 (0.5-3, 0-4) | <0.001 | 1 (0.5-2, 0-4) | 3 (2-4, 0-4) | 0.001 |
| White Matter (4) | 0 (0-0, 0-1) | 0 (0-0, 0-2.5) | 0.730 | 0 (0-0.5, 0-1.5) | 0 (0-0, 0-2) | 0.264 |
| Pons (4) | 0 (0-0, 0-1) | 0 (0-1.5, 0-3.5) | 0.070 | 0 (0-0, 0-0.5) | 0 (0-0.5, 0-3) | 0.276 |
Qualitative scores: 0=no abnormality, 1=possibly abnormal, 2=mildly abnormal, 3=moderately abnormal and 4=severely abnormal; lobar and cerebellar scores are sums of the component scores; all p-values <0.05 are significant after adjustment for multiple comparisons.