Skip to main content
. Author manuscript; available in PMC: 2010 Oct 1.
Published in final edited form as: Genesis. 2009 Oct;47(10):647–658. doi: 10.1002/dvg.20543

Figure-1. Modeling of Tik and constructs.

Figure-1

(a) Molecular model of Drosophila Tik based on coordinates of human CK2α. The location of the two substitutions and ATP are shown in space-filling mode. (b) Alignment of the α and α’ subunits of CK2. The green box is the region of human CK2α proposed to mediate interaction with PP2A (Heriche et al., 1997). Inset (boxed) shows a Motif-Logo of residues from Met161-Leu169 in CK2α subunits. (c) Drosophila CK2α constructs. The locations of the substitutions or deletions are shown relative to key motifs of dCK2α.