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. Author manuscript; available in PMC: 2011 May 25.
Published in final edited form as: Circulation. 2010 May 10;121(20):2211–2220. doi: 10.1161/CIRCULATIONAHA.109.928796

Figure 2.

Figure 2

Adoptive transfer of human HSPCs to NOD/SCID mice following kidney ischemia reperfusion injury decreases mortality and improves kidney function. (A) Plasma creatinine levels on days 1 and 2 following bilateral IRI followed IV injection with PBS (Vehicle, n=16) or 2.5×106 (HSC, n=10) 1day following injury. Data are mean ± SD. (B) Curves showing the proportion of mice with plasma creatinine ≤0.4 mg/dL at each time point following IRI. (C) Survival curves and number at each time point, for mice undergoing bilateral IRI followed IV injection with PBS (vehicle) or 2.5×106 human HSPCs (HSC) 1 day following injury.