Abstract
The serum-growth hormone response to exercise is greater and occurs earlier in juvenile diabetics than in nondiabetics. A simple exercise test has been devised which unequivocally reveals the growth hormone hypersecretion of juvenile diabetics. Using this procedure we have shown that after a period of exceedingly strict metabolic control of the diabetes, complete normalization of growth hormone secretion is attained. It is concluded that the abnormalities in serum growth hormone found in juvenile diabetics are of a metabolic origin.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Christensen N. J. Notes on the glucose oxidase method. Scand J Clin Lab Invest. 1967;19(4):379–384. doi: 10.3109/00365516709090653. [DOI] [PubMed] [Google Scholar]
- FETERIS W. A. A SERUM GLUCOSE METHOD WITHOUT PROTEIN PRECIPITATION. Am J Med Technol. 1965 Jan-Feb;31:17–21. [PubMed] [Google Scholar]
- Hansen A. P. Abnormal serum growth hormone response to exercise in juvenile diabetics. J Clin Invest. 1970 Aug;49(8):1467–1478. doi: 10.1172/JCI106364. [DOI] [PMC free article] [PubMed] [Google Scholar]
- JENNINGS G. H., HAMILTON-PATERSON J. L., MacCALLUM F. O. Fatal case of polio-encephalitis due to poliomyelitis virus. Br Med J. 1949 Jul 23;2(4620):210–213. doi: 10.1136/bmj.2.4620.210. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Johansen K., Hansen A. P. Diurnal serum growth hormone levels in poorly and well-controlled juvenile diabetics. Diabetes. 1971 Apr;20(4):239–245. doi: 10.2337/diab.20.4.239. [DOI] [PubMed] [Google Scholar]
- Laurell S., Tibbling G. Colorimetric micro-determination of free fatty acids in plasma. Clin Chim Acta. 1967 Apr;16(1):57–62. doi: 10.1016/0009-8981(67)90269-0. [DOI] [PubMed] [Google Scholar]
- Lundbaek K., Christensen N. J., Jensen V. A., Johansen K., Olsen T. S., Hansen A. P., Orskov H., Osterby R. Diabetes, diabetic angiopathy, and growth hormone. Lancet. 1970 Jul 18;2(7664):131–133. doi: 10.1016/s0140-6736(70)92706-6. [DOI] [PubMed] [Google Scholar]
- Orskov H., Thomsen H. G., Yde H. Wick chromatography for rapid and reliable immunoassay of insulin, glucagon and growth hormone. Nature. 1968 Jul 13;219(5150):193–195. doi: 10.1038/219193b0. [DOI] [PubMed] [Google Scholar]