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. Author manuscript; available in PMC: 2010 Aug 13.
Published in final edited form as: Hippocampus. 2005;15(4):491–501. doi: 10.1002/hipo.20074

FIGURE 4.

FIGURE 4

Differential response of intact and adrenalectomized (ADX)/clamped rats to complete corticosterone (CORT) withdrawal. A: Adrenalectomy of 3-month-old rats resulted in increased granule cell production. B: Withdrawal of CORT from 3-month-old ADX/clamped rats did not enhance neurogenesis. However, apoptosis rate was significantly increased in both the adult-ADX (C,E) and the early-life ADX/clamped rats (D,F) after CORT withdrawal. (*P < 0.05; ‡P = 0.06; Student’s t-test). GCL, granule cell layer.