Table 1.
Demographic traits of the study sample by polycystic kidney disease diagnosis and kidney function level
| Combined Cohort, n (%)a | ADPKD, ICD9 753.13, n (%)a | Polycystic Kidney Unspecified, ICD9 753.12, n (%)a | |
|---|---|---|---|
| Full Cohort | n = 1913 | n = 496 | n = 1417 |
| Age in years, mean ± SD | 46.7 ± 12.5b | 46.8 ± 12.4b | 46.7 ± 12.5b |
| Male gender | 828 (43.3)b | 221 (44.6)b | 607 (42.8)b |
| Diabetes | 102 (5.3) | 31 (6.3) | 71 (5.0) |
| Cardiovascular disease | 43 (2.2)b | 13 (2.6)b | 30 (2.1) |
| eGFR ≥90 | n = 295 | n = 68 | n = 227 |
| Age in years, mean ± SD | 37.4 ± 12.1 | 36.9 ± 11.9 | 37.6 ± 12.2 |
| Male gender | 94 (31.9) | 23 (33.8) | 71 (31.3) |
| Diabetes | 14 (4.8) | 3 (4.4) | 11 (4.9) |
| Cardiovascular disease | 3 (1.0) | 0 | 3 (1.3) |
| eGFR 60 to 89 | n = 696 | n = 167 | n = 529 |
| Age in years, mean ± SD | 44.1 ± 11.5 | 43.5 ± 11.3 | 44.2 ± 11.6 |
| Male gender | 272 (39.1) | 67 (40.1) | 205 (38.8) |
| Diabetes | 31 (4.5) | 8 (4.8) | 23 (4.4) |
| Cardiovascular disease | 5 (0.7) | 3 (1.8) | 2 (0.4) |
| eGFR 30 to 59 | n = 582 | n = 158 | n = 424 |
| Age in years, mean ± SD | 51.2 ± 11.0 | 50.3 ± 11.0 | 51.5 ± 11.0 |
| Male gender | 299 (51.4) | 79 (50.0) | 220 (51.9) |
| Diabetes | 33 (5.7) | 15 (9.5) | 18 (4.3) |
| Cardiovascular disease | 18 (3.1) | 7 (4.4) | 11 (2.6) |
| eGFR 15 to 29 | n = 205 | n = 60 | n = 145 |
| Age in years, mean ± SD | 53.1 ± 10.1 | 53.4 ± 9.1 | 53.0 ± 10.5 |
| Male gender | 98 (47.8) | 34 (56.7) | 64 (44.1) |
| Diabetes | 13 (6.3) | 3 (5.0) | 10 (6.9) |
| Cardiovascular disease | 8 (3.9) | 1 (1.7) | 7 (4.8) |
| eGFR <15 | n = 135 | n = 43 | n = 92 |
| Age in years, mean ± SD | 52.1 ± 11.2 | 52.7 ± 12.5 | 51.8 ± 10.6 |
| Male gender | 65 (48.2) | 18 (41.9) | 47 (51.1) |
| Diabetes | 11 (8.2) | 2 (4.6) | 9 (9.8) |
| Cardiovascular disease | 9 (6.7) | 2 (4.6) | 7 (7.6) |
a
Percentages reflect proportions within the polycystic kidney diagnosis code category with the indicated demographic or clinical traits (“column percentages”).
There were no statistically significant differences in distributions of listed clinical traits in 753.13 and 743.12 subgroups at the P < 0.05 level.
b
P < 0.05 for variation in the distribution of clinical traits according to eGFR level within a polycystic kidney diagnosis code category.