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. 1972 Nov;51(11):2977–2980. doi: 10.1172/JCI107123

HL-A8: a genetic link between dermatitis herpetiformis and gluten-sensitive enteropathy

Stephen I Katz 1,2,3,4, Z Myron Falchuk 1,2,3,4, Mark V Dahl 1,2,3,4, G Nicholas Rogentine 1,2,3,4, Warren Strober 1,2,3,4
PMCID: PMC292449  PMID: 5080422

Abstract

Histocompatibility antigen HL-A8 was found in 58% of 26 patients with dermatitis herpetiformis (DH) compared to 24% of a normal group. This difference in antigen frequency is significant at the P < 0.003 level. In a previous study, the frequency of this same genetic marker was found to be significantly increased in patients with gluten-sensitive enteropathy (GSE) (88% in patients vs. 22% in controls). The finding of an increased incidence of the HL-A8 antigen in both DH and GSE supports the concept that these diseases are related and provides a genetic basis for the association between the two.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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