Skip to main content
The Journal of Clinical Investigation logoLink to The Journal of Clinical Investigation
. 1965 Mar;44(3):356–365. doi: 10.1172/JCI105149

Decreased Plasma Clearance and Hepatic Extraction of Aldosterone in Patients with Heart Failure*

C A Camargo 1, A J Dowdy 1, E W Hancock 1, J A Luetscher 1,
PMCID: PMC292486  PMID: 14271296

Full text

PDF
356

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ABELSON D., BONDY P. K. Fluorometric determination of delta 4-3-ketosteroids. Arch Biochem Biophys. 1955 Jul;57(1):208–217. doi: 10.1016/0003-9861(55)90193-4. [DOI] [PubMed] [Google Scholar]
  2. AYERS C. R., DAVIS J. O., LIEBERMAN F., CARPENTER C. C., BERMAN M. The effects of chronic hepatic venous congestion on the metabolism of d,1-aldosterone and d-aldosterone. J Clin Invest. 1962 Apr;41:884–895. doi: 10.1172/JCI104545. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. BARGER A. C., MULDOWNEY F. P., LIEBOWITZ M. R. Role of the kidney in the pathogenesis of congestive heart failure. Circulation. 1959 Aug;20(2):273–285. doi: 10.1161/01.cir.20.2.273. [DOI] [PubMed] [Google Scholar]
  4. BUSH I. E. Methods of paper chromatography of steroids applicable to the study of steroids in mammalian blood and tissues. Biochem J. 1952 Jan;50(3):370–378. doi: 10.1042/bj0500370. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. COX J. R., SINGER B., VEREL D. The relationship between urinary aldosterone, plasma volume, extracellular fluid volume and total body water. Clin Sci. 1959 Nov;18:569–578. [PubMed] [Google Scholar]
  6. DAVIS J. O., HOLMAN J. E., CARPENTER C. C., URQUHART J., HIGGINS J. T., Jr AN EXTRA-ADRENAL FACTOR ESSENTIAL FOR CHRONIC RENAL SODIUM RETENTION IN PRESENCE OF INCREASED SODIUM-RETAINING HORMONE. Circ Res. 1964 Jan;14:17–31. doi: 10.1161/01.res.14.1.17. [DOI] [PubMed] [Google Scholar]
  7. DAVIS J. O., HOWELL D. S., HYATT R. E. Sodium excretion in adrenalectomized dogs with chronic cardiac failure produced by pulmonary artery constriction. Am J Physiol. 1955 Nov;183(2):263–268. doi: 10.1152/ajplegacy.1955.183.2.263. [DOI] [PubMed] [Google Scholar]
  8. DAVIS J. O. Mechanisms of salt and water retention in congestive heart failure. The importance of aldosterone. Am J Med. 1960 Sep;29:486–507. doi: 10.1016/0002-9343(60)90045-0. [DOI] [PubMed] [Google Scholar]
  9. DAVIS J. O., PECHET M. M., BALL W. C., Jr, GOODKIND M. J. Increased aldosterone secretion in dogs with right-sided congestive heart failure and in dogs with thoracic inferior vena cava constriction. J Clin Invest. 1957 May;36(5):689–694. doi: 10.1172/JCI103470. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. JOHNSON B. B. Bioassay of adrenal cortical steroids on the basis of electrolyte excretion by rats: effects of 11-desoxy and 11-oxy-steroids. Endocrinology. 1954 Feb;54(2):196–208. doi: 10.1210/endo-54-2-196. [DOI] [PubMed] [Google Scholar]
  11. LARAGH J. H. Hormones and the pathogenesis of congestive heart failure: vasopressin, aldosterone, and angiotensin II. Further evidence for renal-adrenal interaction from studies in hypertension and in cirrhosis. Circulation. 1962 Jun;25:1015–1023. doi: 10.1161/01.cir.25.6.1015. [DOI] [PubMed] [Google Scholar]
  12. LUETSCHER J. A., CAMARGO C. A., COHN A. P., DOWDY A. J., CALLAGHAN A. M. OBSERVATIONS ON METABOLISM OF ALDOSTERONE IN MAN. Ann Intern Med. 1963 Jul;59:1–7. doi: 10.7326/0003-4819-59-1-1. [DOI] [PubMed] [Google Scholar]
  13. LUETSCHER J. A., CAMARGO C. A., HANCOCK E. W., DOWDY A. J., NOKES G. W. OBSERVATIONS OF ALDOSTERONE METABOLISM IN CONGESTIVE HEART FAILURE. Trans Assoc Am Physicians. 1964;77:224–231. [PubMed] [Google Scholar]
  14. LUETSCHER J. A., COHN A. P., CAMARGO C. A., DOWDY A. J., CALLAGHAN A. M. ALDOSTERONE SECRETION AND METABOLISM IN HYPERTHYROIDISM AND MYXEDEMA. J Clin Endocrinol Metab. 1963 Sep;23:873–880. doi: 10.1210/jcem-23-9-873. [DOI] [PubMed] [Google Scholar]
  15. MULLER A. F., VEYRAT R., MANNING E. L. [Study of aldosterone secretion by aldosterone marked with tritium]. Helv Med Acta. 1959 Nov;26:714–719. [PubMed] [Google Scholar]
  16. Myers J. D., Hickam J. B. AN ESTIMATION OF THE HEPATIC BLOOD FLOW AND SPLANCHNIC OXYGEN CONSUMPTION IN HEART FAILURE. J Clin Invest. 1948 Sep;27(5):620–627. doi: 10.1172/JCI102008. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. NAHAS G. G. Spectrophotometric determination of hemoglobin and oxyhemoglobin in whole hemolyzed blood. Science. 1951 Jun 22;113(2947):723–725. doi: 10.1126/science.113.2947.723. [DOI] [PubMed] [Google Scholar]
  18. RAPAPORT E., WEISBART M. H., LEVINE M. The splanchnic blood volume in congestive heart failure. Circulation. 1958 Oct;18(4 Pt 1):581–587. doi: 10.1161/01.cir.18.4.581. [DOI] [PubMed] [Google Scholar]
  19. SANDERS L. L., MELBY J. C. ALDOSTERONE AND THE EDEMA OF CONGESTIVE HEART FAILURE. Arch Intern Med. 1964 Mar;113:331–341. doi: 10.1001/archinte.1964.00280090017004. [DOI] [PubMed] [Google Scholar]
  20. SHERLOCK S. The liver in heart failure; relation of anatomical, functional, and circulatory changes. Br Heart J. 1951 Jul;13(3):273–293. doi: 10.1136/hrt.13.3.273. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. SIEGENTHALER W. E., DOWDY A., LUETSCHER J. A. Determination of the secretion rate of aldosterone in normal man by use of 7-H3-d-aldosterone and acid hydrolysis of urine. J Clin Endocrinol Metab. 1962 Feb;22:172–177. doi: 10.1210/jcem-22-2-172. [DOI] [PubMed] [Google Scholar]
  22. TAIT J. F., LITTLE B., TAIT S. A., FLOOD C. The metabolic clearance rate of aldosterone in pregnant and nonpregnant subjects estimated by both single-injection and constant-infusion methods. J Clin Invest. 1962 Dec;41:2093–2100. doi: 10.1172/JCI104667. [DOI] [PMC free article] [PubMed] [Google Scholar]
  23. TAIT J. F., TAIT S. A., LITTLE B., LAUMAS K. R. The disappearance of 7-H-3-d-aldosterone in the plasma of normal subjects. J Clin Invest. 1961 Jan;40:72–80. doi: 10.1172/JCI104239. [DOI] [PMC free article] [PubMed] [Google Scholar]
  24. WOLFF H. P., KOCZOREK K. R., BUCHBORN E., RIEKER G. Endocrine factors. J Chronic Dis. 1959 May;9(5):554–570. doi: 10.1016/0021-9681(59)90179-1. [DOI] [PubMed] [Google Scholar]
  25. YATES F. E., URQUHART J., HERBST A. L. Impairment of the enzymatic inactivation of adrenal cortical hormones following passive venous congestion of the liver. Am J Physiol. 1958 Jul;194(1):65–71. doi: 10.1152/ajplegacy.1958.194.1.65. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Clinical Investigation are provided here courtesy of American Society for Clinical Investigation

RESOURCES