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. 1965 Aug;44(8):1295–1310. doi: 10.1172/JCI105236

Load, Work, and Velocity of Muscle Shortening of the Left Ventricle in Normal and Abnormal Human Hearts*

D E L Wilcken 1,†
PMCID: PMC292608  PMID: 14322037

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ABBOTT B. C., MOMMAERTS W. F. A study of inotropic mechanisms in the papillary muscle preparation. J Gen Physiol. 1959 Jan 20;42(3):533–551. doi: 10.1085/jgp.42.3.533. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. BARNETT G. O., GREENFIELD J. C., Jr, FOX S. M., 3rd The technique of estimating the instantaneous aortic blood velocity in man from the pressure gradient. Am Heart J. 1961 Sep;62:359–366. doi: 10.1016/0002-8703(61)90402-1. [DOI] [PubMed] [Google Scholar]
  3. BICKFORD R. G., POOLE E. W., McCARTHY C. E. Some applications in EEG analysis. Fed Proc. 1962 Jan-Feb;21:103–108. [PubMed] [Google Scholar]
  4. BING R. J., SIEGEL A., VITALE A., BALBONI F., SPARKS E., TAESCHLER M., KLAPPER M., EDWARDS S. Metabolic studies on the human heart in vivo. I. Studies on carbohydrate metabolism of the human heart. Am J Med. 1953 Sep;15(3):284–296. doi: 10.1016/0002-9343(53)90082-5. [DOI] [PubMed] [Google Scholar]
  5. BLAIN J. M., SCHAFER H., SIEGEL A. L., BING R. J. Studies on myocardial metabolism. VI. Myocardial metabolism in congestive failure. Am J Med. 1956 Jun;20(6):820–833. doi: 10.1016/0002-9343(56)90203-0. [DOI] [PubMed] [Google Scholar]
  6. BRAUNWALD E., AYGEN M. M. IDIOPATHIC MYOCARDIAL HYPERTROPHY WITHOUT CONGESTIVE HEART FAILURE OR OBSTRUCTION TO BLOOD FLOW. CLINICAL, HEMODYNAMIC AND ANGIOCARDIOGRAPHIC STUDIES IN FOURTEEN PATIENTS. Am J Med. 1963 Jul;35:7–19. doi: 10.1016/0002-9343(63)90159-1. [DOI] [PubMed] [Google Scholar]
  7. BRISTOW J. D., CRISLIP R. L., FARREHI C., HARRIS W. E., LEWIS R. P., SUTHERLAND D. W., GRISWOLD H. E. LEFT VENTRICULAR VOLUME MEASUREMENTS IN MAN BY THERMODILUTION. J Clin Invest. 1964 Jun;43:1015–1024. doi: 10.1172/JCI104985. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. BRITMAN N. A., LEVINE H. J. CONTRACTILE ELEMENT WORK: A MAJOR DETERMINANT OF MYOCARDIAL OXYGEN CONSUMPTION. J Clin Invest. 1964 Jul;43:1397–1408. doi: 10.1172/JCI105015. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. BURCH G. E., RAY C. T., CRONVICH J. A. Certain mechanical peculiarities of the human cardiac pump in normal and diseased states. Circulation. 1952 Apr;5(4):504–513. doi: 10.1161/01.cir.5.4.504. [DOI] [PubMed] [Google Scholar]
  10. BURTON A. C. The importance of the shape and size of the heart. Am Heart J. 1957 Dec;54(6):801–810. doi: 10.1016/0002-8703(57)90186-2. [DOI] [PubMed] [Google Scholar]
  11. CHAPMAN C. B., BAKER O., MITCHELL J. H. Left ventricular function at rest and during exercise. J Clin Invest. 1959 Jul;38(7):1202–1213. doi: 10.1172/JCI103895. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. CHAPMAN C. B., BAKER O., REYNOLDS J., BONTE F. J. Use of biplane cinefluorography for measurement of ventricular volume. Circulation. 1958 Dec;18(6):1105–1117. doi: 10.1161/01.cir.18.6.1105. [DOI] [PubMed] [Google Scholar]
  13. DODGE H. T., SANDLER H., BALLEW D. W., LORD J. D., Jr The use of biplane angiocardigraphy for the measurement of left ventricular volume in man. Am Heart J. 1960 Nov;60:762–776. doi: 10.1016/0002-8703(60)90359-8. [DOI] [PubMed] [Google Scholar]
  14. ELLIS R. M., FRANKLIN D. L., RUSHMER R. F. Left ventricular dimensions recorded by sonocardiometry. Circ Res. 1956 Nov;4(6):684–688. doi: 10.1161/01.res.4.6.684. [DOI] [PubMed] [Google Scholar]
  15. FOLSE R., BRAUNWALD E. Determination of fraction of left ventricular volume ejected per beat and of ventricular end-diastolic and residual volumes. Experimental and clinical observations with a precordial dilution technic. Circulation. 1962 Apr;25:674–685. doi: 10.1161/01.cir.25.4.674. [DOI] [PubMed] [Google Scholar]
  16. GORLIN R., ROLETT E. L., YURCHAK P. M., ELLIOTT W. C. LEFT VENTRICULAR VOLUME IN MAN MEASURED BY THERMODILUTION. J Clin Invest. 1964 Jun;43:1203–1221. doi: 10.1172/JCI105004. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. HAWTHORNE E. W. Instantaneous dimensional changes of the left ventricle in dogs. Circ Res. 1961 Jan;9:110–119. doi: 10.1161/01.res.9.1.110. [DOI] [PubMed] [Google Scholar]
  18. HEFNER L. L., SHEFFIELD L. T., COBBS G. C., KLIP W. Relation between mural force and pressure in the left ventricle of the dog. Circ Res. 1962 Oct;11:654–663. doi: 10.1161/01.res.11.4.654. [DOI] [PubMed] [Google Scholar]
  19. HOLT J. P. Estimation of the residual volume of the ventricle of the dog's heart by two indicator dilution technics. Circ Res. 1956 Mar;4(2):187–195. doi: 10.1161/01.res.4.2.187. [DOI] [PubMed] [Google Scholar]
  20. Hill A. V. The absolute mechanical efficiency of the contraction of an isolated muscle. J Physiol. 1913 Aug 18;46(6):435–469. doi: 10.1113/jphysiol.1913.sp001600. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. LEVINE H. J., BRITMAN N. A. FORCE-VELOCITY RELATIONS IN THE INTACT DOG HEART. J Clin Invest. 1964 Jul;43:1383–1396. doi: 10.1172/JCI105014. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. LINZBACH A. J. Heart failure from the point of view of quantitative anatomy. Am J Cardiol. 1960 Mar;5:370–382. doi: 10.1016/0002-9149(60)90084-9. [DOI] [PubMed] [Google Scholar]
  23. RAPAPORT E., WIEGAND B. D., BRISTOW J. D. Estimation of left ventricular residual volume in the dog by a thermodilution method. Circ Res. 1962 Nov;11:803–810. doi: 10.1161/01.res.11.5.803. [DOI] [PubMed] [Google Scholar]
  24. RUSHMER R. F., THAL N. The mechanics of ventricular contraction; a cinefluorographic study. Circulation. 1951 Aug;4(2):219–228. doi: 10.1161/01.cir.4.2.219. [DOI] [PubMed] [Google Scholar]
  25. SANDLER H., DODGE H. T., HAY R. E., RACKLEY C. E. Quantitation of valvular insufficiency in man by angiocardiography. Am Heart J. 1963 Apr;65:501–513. doi: 10.1016/0002-8703(63)90100-5. [DOI] [PubMed] [Google Scholar]
  26. SONNENBLICK E. H., DOWNING S. E. Afterload as a primary determinat of ventricular performance. Am J Physiol. 1963 Apr;204:604–610. doi: 10.1152/ajplegacy.1963.204.4.604. [DOI] [PubMed] [Google Scholar]
  27. SONNENBLICK E. H. Force-velocity relations in mammalian heart muscle. Am J Physiol. 1962 May;202:931–939. doi: 10.1152/ajplegacy.1962.202.5.931. [DOI] [PubMed] [Google Scholar]
  28. SWAN H. J., BECK W. Ventricular nonmixing as a source of error in the estimation of ventricular volume by the indicator-dilution technic. Circ Res. 1960 Sep;8:989–998. doi: 10.1161/01.res.8.5.989. [DOI] [PubMed] [Google Scholar]
  29. WILCKEN D. E., CHARLIER A. A., HOFFMAN J. I., GUZ A. EFFECTS OF ALTERATIONS IN AORTIC IMPEDANCE ON THE PERFORMANCE OF THE VENTRICLES. Circ Res. 1964 Apr;14:283–293. doi: 10.1161/01.res.14.4.283. [DOI] [PubMed] [Google Scholar]
  30. WILCKEN D. E. THE MEASUREMENT OF THE END-DIASTOLIC AND END-SYSTOLIC, OR RESIDUAL, VOLUMES OF THE LEFT VENTRICLE IN MAN, USING A DYE-DILUTION METHOD. Clin Sci. 1965 Feb;28:131–146. [PubMed] [Google Scholar]
  31. WILSON M. F. Left ventricular diameter, posture, and exercise. Circ Res. 1962 Jul;11:90–95. [PubMed] [Google Scholar]

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