Skip to main content
PMC home page
The Journal of Clinical Investigation logoLink to The Journal of Clinical Investigation
. 1966 Jan;45(1):40–50. doi: 10.1172/JCI105322

Biochemical studies of energy production in the failing human heart.

C A Chidsey, E C Weinbach, P E Pool, A G Morrow
PMCID: PMC292665  PMID: 5901178

Full text

PDF
40

Images in this article

45Image
on p.45

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BING R. J., SIEGEL A., VITALE A., BALBONI F., SPARKS E., TAESCHLER M., KLAPPER M., EDWARDS S. Metabolic studies on the human heart in vivo. I. Studies on carbohydrate metabolism of the human heart. Am J Med. 1953 Sep;15(3):284–296. doi: 10.1016/0002-9343(53)90082-5. [DOI] [PubMed] [Google Scholar]
  2. BING R. J., WU C., GUDBJARNASON S. MECHANISM OF HEART FAILURE. Circ Res. 1964 Nov;15:SUPPL 2–2:69. [PubMed] [Google Scholar]
  3. BLAIN J. M., SCHAFER H., SIEGEL A. L., BING R. J. Studies on myocardial metabolism. VI. Myocardial metabolism in congestive failure. Am J Med. 1956 Jun;20(6):820–833. doi: 10.1016/0002-9343(56)90203-0. [DOI] [PubMed] [Google Scholar]
  4. BUFFA P., CARAFOLI E., MUSCATELLO U. MITOCHONDRIAL BIOCHEMICAL LESION AND PYROGENIC EFFECT OF PENTACHLOROPHENOL. Biochem Pharmacol. 1963 Aug;12:769–778. doi: 10.1016/0006-2952(63)90107-2. [DOI] [PubMed] [Google Scholar]
  5. CAIN D. F., DAVIES R. E. Breakdown of adenosine triphosphate during a single contraction of working muscle. Biochem Biophys Res Commun. 1962 Aug 7;8:361–366. doi: 10.1016/0006-291x(62)90008-6. [DOI] [PubMed] [Google Scholar]
  6. CAULFIELD J. B. Effects of varying the vehicle for OsO4 in tissue fixation. J Biophys Biochem Cytol. 1957 Sep 25;3(5):827–830. doi: 10.1083/jcb.3.5.827. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Chappell J. B. The oxidation of citrate, isocitrate and cis-aconitate by isolated mitochondria. Biochem J. 1964 Feb;90(2):225–237. doi: 10.1042/bj0900225. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. FEINSTEIN M. B. Effects of experimental congestive heart failure, ouabain, and asphyxia on the high-energy phosphate and creatine content of the guinea pig heart. Circ Res. 1962 Mar;10:333–346. doi: 10.1161/01.res.10.3.333. [DOI] [PubMed] [Google Scholar]
  9. FOX A. C., WIKLER N. S., REED G. E. HIGH ENERGY PHOSPHATE COMPOUNDS IN THE MYOCARDIUM DURING EXPERIMENTAL CONGESTIVE HEART FAILURE. PURINE AND PYRIMIDINE NUCLEOTIDES, CREATINE, AND CREATINE PHOSPHATE IN NORMAL AND IN FAILING HEARTS. J Clin Invest. 1965 Feb;44:202–218. doi: 10.1172/JCI105135. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. FURCHGOTT R. F., DE GUBAREFF T. The high energy phosphate content of cardiac muscle under various experimental conditions which alter contractile strength. J Pharmacol Exp Ther. 1958 Nov;124(3):203–218. [PubMed] [Google Scholar]
  11. GREINER T. The relationship of force of contraction to high-energy phosphate in heart muscle. J Pharmacol Exp Ther. 1952 Jun;105(2):178–195. [PubMed] [Google Scholar]
  12. HATEFI Y., JURTSHUK P., HAAVIK A. G. Studies on the electron transport system. 32. Respiratory control in beef heart mitochondria. Arch Biochem Biophys. 1961 Jul;94:148–155. doi: 10.1016/0003-9861(61)90022-4. [DOI] [PubMed] [Google Scholar]
  13. KATZ L. N., FEINBERG H., SHAFFER A. B. Hemodynamic aspects of congestive heart failure. Circulation. 1960 Jan;21:95–111. doi: 10.1161/01.cir.21.1.95. [DOI] [PubMed] [Google Scholar]
  14. LARDY H. A., JOHNSON D., McMURRAY W. C. Antibiotics as tools for metabolic studies. I. A survey of toxic antibiotics in respiratory, phosphorylative and glycolytic systems. Arch Biochem Biophys. 1958 Dec;78(2):587–597. doi: 10.1016/0003-9861(58)90383-7. [DOI] [PubMed] [Google Scholar]
  15. LUFT R., IKKOS D., PALMIERI G., ERNSTER L., AFZELIUS B. A case of severe hypermetabolism of nonthyroid origin with a defect in the maintenance of mitochondrial respiratory control: a correlated clinical, biochemical, and morphological study. J Clin Invest. 1962 Sep;41:1776–1804. doi: 10.1172/JCI104637. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. MEERSON F. Z. Compensatory hyperfunction of the heart and cardiac insufficiency. Circ Res. 1962 Mar;10:250–258. doi: 10.1161/01.res.10.3.250. [DOI] [PubMed] [Google Scholar]
  17. MEERSON F. Z., ZALETAYEVA T. A., LAGUTCHEV S. S., PSHENNIKOVA M. G. STRUCTURE AND MASS OF MITOCHONDRIA IN THE PROCESS OF COMPENSATORY HYPERFUNCTION AND HYPERTROPHY OF THE HEART. Exp Cell Res. 1964 Dec;36:568–578. doi: 10.1016/0014-4827(64)90313-1. [DOI] [PubMed] [Google Scholar]
  18. MORROW A. G., CLARK W. D., HARRISON D. C., BRAUNWALD E. PROSTHETIC REPLACEMENT OF THE MITRAL VALVE. OPERATIVE METHODS AND THE RESULTS OF PREOPERATIVE AND POSTOPERATIVE HEMODYNAMIC ASSESSMENTS. Circulation. 1964 Apr;29:SUPPL–SUPPL13. [PubMed] [Google Scholar]
  19. OLSON R. E. ABNORMALITIES OF MYOCARDIAL METABOLISM. Circ Res. 1964 Nov;15:SUPPL 2–2:119. [PubMed] [Google Scholar]
  20. PLAUT G. W., GERTLER M. M. Oxidative phosphorylation studies in normal and experimentally produced congestive heart failure in guinea pigs: a comparison. Ann N Y Acad Sci. 1959 Feb 6;72(12):515–517. doi: 10.1111/j.1749-6632.1959.tb44178.x. [DOI] [PubMed] [Google Scholar]
  21. PROCITA L., SCHWARTZ A., LEE K. S. OXIDATIVE PHOSPHORYLATION IN THE FAILING DOG HEART-LUNG PREPARATION. Circ Res. 1965 Apr;16:391–395. doi: 10.1161/01.res.16.4.391. [DOI] [PubMed] [Google Scholar]
  22. RACKER E. Mechanisms of synthesis of adenosine triphosphate. Adv Enzymol Relat Subj Biochem. 1961;23:323–399. doi: 10.1002/9780470122686.ch7. [DOI] [PubMed] [Google Scholar]
  23. SCHWARTZ A., LEE K. S. Study of heart mitochondria and glycolytic metabolism in experimentally induced cardiac failure. Circ Res. 1962 Mar;10:321–332. doi: 10.1161/01.res.10.3.321. [DOI] [PubMed] [Google Scholar]
  24. SONNENBLICK E. H., SPOTNITZ H. M., SPIRO D. ROLE OF THE SARCOMERE IN VENTRICULAR FUNCTION AND THE MECHANISM OF HEART FAILURE. Circ Res. 1964 Nov;15:SUPPL 2–2:81. doi: 10.1161/01.res.15.3.270. [DOI] [PubMed] [Google Scholar]
  25. SZEKERES L., SCHEIN M. Cell metabolism of the overloaded mammalian heart in situ. Cardiologia. 1959;34(1):19–27. doi: 10.1159/000166392. [DOI] [PubMed] [Google Scholar]
  26. WEINBACH E. C. Stability of oxidative phosphorylation and related reactions in isolated liver mitochondria. J Biol Chem. 1959 Jun;234(6):1580–1586. [PubMed] [Google Scholar]
  27. WOLLENBERGER A., KLEITKE B., RAABE G. Some metabolic characteristics of mitochondria from chronically overloaded, hypertrophied hearts. Exp Mol Pathol. 1963 Jun;2:251–260. doi: 10.1016/0014-4800(63)90040-6. [DOI] [PubMed] [Google Scholar]
  28. WOLLENBERGER A., SCHULZE W. Mitochondrial alterations in the myocardium of dogs with aortic stenosis. J Biophys Biochem Cytol. 1961 Jun;10:285–288. doi: 10.1083/jcb.10.2.285. [DOI] [PMC free article] [PubMed] [Google Scholar]
  29. Zierler K. L. THEORY OF THE USE OF ARTERIOVENOUS CONCENTRATION DIFFERENCES FOR MEASURING METABOLISM IN STEADY AND NON-STEADY STATES. J Clin Invest. 1961 Dec;40(12):2111–2125. doi: 10.1172/JCI104437. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Journal of Clinical Investigation are provided here courtesy of American Society for Clinical Investigation

RESOURCES