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. 1966 Jan;45(1):155–163. doi: 10.1172/JCI105320

Free thyroxine in human serum: simplified measurement with the aid of magnesium precipitation.

K Sterling, M A Brenner
PMCID: PMC292676  PMID: 4158931

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BALFOUR W. E., TUNNICLIFFE H. E. Thyroxine binding by serum proteins. J Physiol. 1960 Aug;153:179–198. doi: 10.1113/jphysiol.1960.sp006527. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. BERSON S. A., YALOW R. S., SORRENTINO J., ROSWIT B. The determination of thyroidal and renal plasma I131 clearance rates as a routine diagnostic test of thyroid dysfunction. J Clin Invest. 1952 Feb;31(2):141–158. doi: 10.1172/JCI102585. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. DOWLING J. T., FREINKEL N., INGBAR S. H. Effect of diethylstilbestrol on the binding of thyroxine in serum. J Clin Endocrinol Metab. 1956 Nov;16(11):1491–1506. doi: 10.1210/jcem-16-11-1491. [DOI] [PubMed] [Google Scholar]
  4. DOWLING J. T., FREINKEL N., INGBAR S. H. Thyroxine-binding by sera of pregnant women, newborn infants, and women with spontaneous abortion. J Clin Invest. 1956 Nov;35(11):1263–1276. doi: 10.1172/JCI103381. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. DOWLING J. T., FREINKEL N., INGBAR S. H. Thyroxine-binding by sera of pregnant women. J Clin Endocrinol Metab. 1956 Feb;16(2):280–282. doi: 10.1210/jcem-16-2-280. [DOI] [PubMed] [Google Scholar]
  6. DOWLING J. T., INGBAR S. H., FREINKEL N. Iodine metabolism in hydatidiform mole and choriocarcinoma. J Clin Endocrinol Metab. 1960 Jan;20:1–12. doi: 10.1210/jcem-20-1-1. [DOI] [PubMed] [Google Scholar]
  7. ENGBRING N. H., ENGSTROM W. W. Effects of estrogen and testosterone on circulating thyroid hormone. J Clin Endocrinol Metab. 1959 Jul;19(7):783–796. doi: 10.1210/jcem-19-7-783. [DOI] [PubMed] [Google Scholar]
  8. HOCH H., SINNETT S. L., MILLER P. O., MAHADY I. B. DIALYZABLE THYROID HORMONE-BINDING MATERIAL IN HUMAN SERUM. Biochemistry. 1965 May;4:931–939. doi: 10.1021/bi00881a020. [DOI] [PubMed] [Google Scholar]
  9. INGBAR S. H., FREINKEL N. Regulation of the peripheral metabolism of the thyroid hormones. Recent Prog Horm Res. 1960;16:353–403. [PubMed] [Google Scholar]
  10. INGBAR S. H., WATERHOUSE C., CUSHMAN P. OBSERVATIONS ON THE NATURE OF THE UNDERLYING DISORDER AND THE OCCURRENCE OF ASSOCIATED PLASMA TRANSPORT ABNORMALITIES IN A PATIENT WITH AN IDIOPATHIC INCREASE IN THE PLASMA THYROXINE-BINDING GLOBULIN. J Clin Invest. 1964 Dec;43:2266–2271. doi: 10.1172/JCI105100. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Ingbar S. H., Braverman L. E., Dawber N. A., Lee G. Y. A new method for measuring the free thyroid hormone in human serum and an analysis of the factors that influence its concentration. J Clin Invest. 1965 Oct;44(10):1679–1689. doi: 10.1172/JCI105275. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. LEE N. D., HENRY R. J., GOLUB O. J. DETERMINATION OF THE FREE THYROXINE CONTENT OF SERUM. J Clin Endocrinol Metab. 1964 Jun;24:486–495. doi: 10.1210/jcem-24-6-486. [DOI] [PubMed] [Google Scholar]
  13. MYANT N. B., OSORIO C. Paper electrophoresis of thyroxine in tris-maleate buffer. J Physiol. 1960 Jul;152:601–612. doi: 10.1113/jphysiol.1960.sp006511. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. NICOLOFF J. T., NICOLOFF R., DOWLING J. T. Evaluation of vaginal smear, serum gonadotropin, protein-bound iodine, and thyroxine-binding as measures of placental adequacy. J Clin Invest. 1962 Nov;41:1998–2011. doi: 10.1172/JCI104658. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. OPPENHEIMER J. H., SQUEF R., SURKS M. I., HAUER H. BINDING OF THYROXINE BY SERUM PROTEINS EVALUATED BY EQUILIBRUM DIALYSIS AND ELECTROPHORETIC TECHNIQUES. ALTERATIONS IN NONTHYROIDAL ILLNESS. J Clin Invest. 1963 Nov;42:1769–1782. doi: 10.1172/JCI104862. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. OPPENHEIMER J. H., SURKS M. I. DETERMINATION OF FREE THYROXINE IN HUMAN SERUM: A THEORETICAL AND EXPERIMENTAL ANALYSIS. J Clin Endocrinol Metab. 1964 Aug;24:785–793. doi: 10.1210/jcem-24-8-785. [DOI] [PubMed] [Google Scholar]
  17. ROBBINS J., NELSON J. H. Thyroxinebinding by serum protein in pregnancy and in the newborn. J Clin Invest. 1958 Feb;37(2):153–159. doi: 10.1172/JCI103593. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. ROBBINS J., RALL J. E. Proteins associated with the thyroid hormones. Physiol Rev. 1960 Jul;40:415–489. doi: 10.1152/physrev.1960.40.3.415. [DOI] [PubMed] [Google Scholar]
  19. ROBBINS J., RALL J. E. The interaction of thyroid hormones and protein in biological fluids. Recent Prog Horm Res. 1957;13:161–208. [PubMed] [Google Scholar]
  20. STERLING K., CHODOS R. B. Radiothyroxine turnover studies in myxedema, thyrotoxicosis, and hypermetabolism without endocrine disease. J Clin Invest. 1956 Jul;35(7):806–813. doi: 10.1172/JCI103333. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. STERLING K., HEGEDUS A. Measurement of free thyroxine concentration in human serum. J Clin Invest. 1962 May;41:1031–1040. doi: 10.1172/JCI104553. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. STERLING K. MOLECULAR STRUCTURE OF THYROXINE IN RELATION TO ITS BINDING BY HUMAN SERUM ALBUMIN. J Clin Invest. 1964 Sep;43:1721–1729. doi: 10.1172/JCI105047. [DOI] [PMC free article] [PubMed] [Google Scholar]
  23. STERLING K., ROSEN P., TABACHNICK M. Equilibrium dialysis studies of the binding of thyroxine by human serum albumin. J Clin Invest. 1962 May;41:1021–1030. doi: 10.1172/JCI104552. [DOI] [PMC free article] [PubMed] [Google Scholar]
  24. STERLING K. Radiothyroxine turnover studies in thyroid disease after therapy. J Clin Invest. 1958 Oct;37(10):1348–1356. doi: 10.1172/JCI103724. [DOI] [PMC free article] [PubMed] [Google Scholar]
  25. STERLING K. THYROXINE IN BLOOD. Mayo Clin Proc. 1964 Aug;39:586–608. [PubMed] [Google Scholar]
  26. SURKS M. I., OPPENHEIMER J. H. POSTOPERATIVE CHANGES IN THE CONCENTRATION OF THYROXINE-BINDING PREALBUMIN AND SERUM FREE THYROXINE. J Clin Endocrinol Metab. 1964 Aug;24:794–802. doi: 10.1210/jcem-24-8-794. [DOI] [PubMed] [Google Scholar]
  27. TORIBARA T. Y., TEREPKA A. R., DEWEY P. A. The ultrafiltrable calcium of human serum. I. Ultrafiltration methods and normal values. J Clin Invest. 1957 May;36(5):738–748. doi: 10.1172/JCI103477. [DOI] [PMC free article] [PubMed] [Google Scholar]
  28. WALSER M. Ion association. VI. Interactions between calcium, magnesium, inorganic phosphate, citrate and protein in normal human plasma. J Clin Invest. 1961 Apr;40:723–730. doi: 10.1172/JCI104306. [DOI] [PMC free article] [PubMed] [Google Scholar]

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