Skip to main content
The Journal of Clinical Investigation logoLink to The Journal of Clinical Investigation
. 1966 Apr;45(4):562–572. doi: 10.1172/JCI105370

The renal response to acid loads in metabolic alkalosis; an assessment of the mechanisms regulating acid excretion.

R L Tannen, H L Bleich, W B Schwartz
PMCID: PMC292730  PMID: 5937027

Full text

PDF
562

Images in this article

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ATKINS E. L., SCHWARTZ W. B. Factors governing correction of the alkalosis associated with potassium deficiency; the critical role of chloride in the recovery process. J Clin Invest. 1962 Feb;41:218–229. doi: 10.1172/JCI104473. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. BANK N., SCHWARTZ W. B. The influence of anion penetrating ability on urinary acidification and the excretion of titratable acid. J Clin Invest. 1960 Oct;39:1516–1525. doi: 10.1172/JCI104171. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. EPSTEIN F. H., KLEEMAN C. R., LAMDIN E., RUBINI M. E. Studies of the antidiuresis of quiet standing: observations upon electrolyte and acid-base excretion during sulfate diuresis. J Clin Invest. 1956 Mar;35(3):308–313. doi: 10.1172/JCI103279. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. GULYASSY P. F., VAN YPERSELE DE STRIHOU C., SCHWARTZ W. B. On the mechanism of nitrate-induced alkalosis. The possible role of selective chloride depletion in acid-base regulation. J Clin Invest. 1962 Oct;41:1850–1862. doi: 10.1172/JCI104642. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. LAUSON H. D., THOMPSON D. D. Effects in dogs of decrease in glomerular filtration rate on cation excretion during intravenous administration of unreabsorbable anions. Am J Physiol. 1958 Jan;192(1):198–208. doi: 10.1152/ajplegacy.1957.192.1.198. [DOI] [PubMed] [Google Scholar]
  6. LOGSDON E. E. A method for the determination of ammonia in biological materials on the autoanalyzer. Ann N Y Acad Sci. 1960 Jul 22;87:801–807. doi: 10.1111/j.1749-6632.1960.tb23237.x. [DOI] [PubMed] [Google Scholar]
  7. NEEDLE M. A., KALOYANIDES G. J., SCHWARTZ W. B. THE EFFECTS OF SELECTIVE DEPLETION OF HYDROCHLORIC ACID ON ACID-BASE AND ELECTROLYTE EQUILIBRIUM. J Clin Invest. 1964 Sep;43:1836–1846. doi: 10.1172/JCI105057. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. POLAK A., HAYNIE G. D., HAYS R. M., SCHWARTZ W. B. Effects of chronic hypercapnia on electrolyte and acid-base equilibrium. I. Adaptation. J Clin Invest. 1961 Jul;40:1223–1237. doi: 10.1172/JCI104353. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. RELMAN A. S., LENNON E. J., LEMANN J., Jr Endogenous production of fixed acid and the measurement of the net balance of acid in normal subjects. J Clin Invest. 1961 Sep;40:1621–1630. doi: 10.1172/JCI104384. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. SCHWARTZ W. B., JENSON R. L., RELMAN A. S. Acidification of the urine and increased ammonium excretion without change in acid-base equilibrium: sodium reabsorption as a stimulus to the acidifying process. J Clin Invest. 1955 May;34(5):673–680. doi: 10.1172/JCI103117. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. SCHWARTZ W. B., JENSON R. L., RELMAN A. S. The disposition of acid administered to sodium-depleted subjects: the renal response and the role of the whole body buffers. J Clin Invest. 1954 Apr;33(4):587–597. doi: 10.1172/JCI102930. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. SULLIVAN L. P., WILDE W. S., MALVIN R. L. Renal transport sites for K, H and NH3. Effect of impermeant anions on their transport. Am J Physiol. 1960 Feb;198:244–254. doi: 10.1152/ajplegacy.1960.198.2.244. [DOI] [PubMed] [Google Scholar]
  13. Sartorius O. W., Roemmelt J. C., Pitts R. F., Calhoon D., Miner P. THE RENAL REGULATION OF ACID-BASE BALANCE IN MAN. IV. THE NATURE OF THE RENAL COMPENSATIONS IN AMMONIUM CHLORIDE ACIDOSIS. J Clin Invest. 1949 May;28(3):423–439. doi: 10.1172/JCI102087. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Journal of Clinical Investigation are provided here courtesy of American Society for Clinical Investigation

RESOURCES