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. 1966 Oct;45(10):1535–1542. doi: 10.1172/JCI105460

Studies on digitalis. XVI. Effects on myocardial oxygen consumption.

J W Covell, E Braunwald, J Ross Jr, E H Sonnenblick
PMCID: PMC292835  PMID: 5925512

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BING R. J., MARAIST F. M., DAMMANN J. F., Jr, DRAPER A., Jr, HEIMBECKER R., DALEY R., GERARD R., CALAZEL P. Effect of strophanthus on coronary blood flow and cardiac oxygen consumption of normal and failing human hearts. Circulation. 1950 Oct;2(4):513–516. doi: 10.1161/01.cir.2.4.513. [DOI] [PubMed] [Google Scholar]
  2. BLAIN J. M., EDDLEMAN E. E., SIEGEL A., BING R. J. Studies on myocardial metabolism. V. The effects of lanatoside-C on the metabolism of the human heart. J Clin Invest. 1956 Mar;35(3):314–321. doi: 10.1172/JCI103280. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Braunwald E., Bloodwell R. D., Goldberg L. I., Morrow A. G. STUDIES ON DIGITALIS. IV. OBSERVATIONS IN MAN ON THE EFFECTS OF DIGITALIS PREPARATIONS ON THE CONTRACTILITY OF THE NON-FAILING HEART AND ON TOTAL VASCULAR RESISTANCE. J Clin Invest. 1961 Jan;40(1):52–59. doi: 10.1172/JCI104236. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. LANGEMANN H., BRODY T. M., BAIN J. A. In vitro effects of ouabain on slices and mitochondrial preparations from heart and brain. J Pharmacol Exp Ther. 1953 Jul;108(3):274–280. [PubMed] [Google Scholar]
  5. LEE K. S. A new technique for the simultaneous recording of oxygen consumption and contraction of muscle: the effect of ouabain on cat papillary muscle. J Pharmacol Exp Ther. 1953 Nov;109(3):304–312. [PubMed] [Google Scholar]
  6. LEE K. S., YU D. H., LEE D. I., BURSTEIN R. The influence of potassium and calcium on the effect of ouabain on cat papillary muscles. J Pharmacol Exp Ther. 1961 May;132:139–148. [PubMed] [Google Scholar]
  7. MASON D. T., BRAUNWALD E. STUDIES ON DIGITALIS. X. EFFECTS OF OUABAIN ON FOREARM VASCULAR RESISTANCE AND VENOUS TONE IN NORMAL SUBJECTS AND IN PATIENTS IN HEART FAILURE. J Clin Invest. 1964 Mar;43:532–543. doi: 10.1172/JCI104939. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. MONROE R. G., FRENCH G. N. Left ventricular pressure-volume relationships and myocardial oxygen consumption in the isolated heart. Circ Res. 1961 Mar;9:362–374. doi: 10.1161/01.res.9.2.362. [DOI] [PubMed] [Google Scholar]
  9. Mason D. T., Braunwald E. STUDIES ON DIGITALIS. IX. EFFECTS OF OUABAIN ON THE NONFAILING HUMAN HEART. J Clin Invest. 1963 Jul;42(7):1105–1111. doi: 10.1172/JCI104796. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. RODBARD S., WILLIAMS F., WILLIAMS C. The spherical dynamics of the heart (myocardial tension, oxygen consumption, coronary blood flow and efficiency). Am Heart J. 1959 Mar;57(3):348–360. doi: 10.1016/0002-8703(59)90316-3. [DOI] [PubMed] [Google Scholar]
  11. ROSS J., Jr, SONNENBLICK E. H., KAISER G. A., FROMMER P. L., BRAUNWALD E. ELECTROAUGMENTATION OF VENTRICULAR PERFORMANCE AND OXYGEN CONSUMPTION BY REPETITIVE APPLICATION OF PAIRED ELECTRICAL STIMULI. Circ Res. 1965 Apr;16:332–342. doi: 10.1161/01.res.16.4.332. [DOI] [PubMed] [Google Scholar]
  12. SARNOFF S. J., BRAUNWALD E., WELCH G. H., Jr, CASE R. B., STAINSBY W. N., MACRUZ R. Hemodynamic determinants of oxygen consumption of the heart with special reference to the tension-time index. Am J Physiol. 1958 Jan;192(1):148–156. doi: 10.1152/ajplegacy.1957.192.1.148. [DOI] [PubMed] [Google Scholar]
  13. SARNOFF S. J., GILMORE J. P., WALLACE A. G., SKINNER N. S., Jr, MITCHELL J. H., DAGGETT W. M. EFFECT OF ACETYL STROPHANTHIDIN THERAPY ON CARDIAC DYNAMICS, OXYGEN CONSUMPTION AND EFFICIENCY IN THE ISOLATED HEART WITH AND WITHOUT HYPOXIA. Am J Med. 1964 Jul;37:3–13. doi: 10.1016/0002-9343(64)90207-4. [DOI] [PubMed] [Google Scholar]
  14. Sonnenblick E. H., Ross J., Jr, Covell J. W., Kaiser G. A., Braunwald E. Velocity of contraction as a determinant of myocardial oxygen consumption. Am J Physiol. 1965 Nov;209(5):919–927. doi: 10.1152/ajplegacy.1965.209.5.919. [DOI] [PubMed] [Google Scholar]
  15. WEISSLER A. M., GAMEL W. G., GRODE H. E., COHEN S., SCHOENFELD C. D. THE EFFECT OF DIGITALIS ON VENTRICULAR EJECTION IN NORMAL HUMAN SUBJECTS. Circulation. 1964 May;29:721–729. doi: 10.1161/01.cir.29.5.721. [DOI] [PubMed] [Google Scholar]

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