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. 1958 Feb;37(2):166–171. doi: 10.1172/JCI103595

STUDIES ON THE BIOCHEMICAL DEFECT OF PERNICIOUS ANEMIA. I. IN VITRO OBSERVATIONS ON OXYGEN CONSUMPTION, HEME SYNTHESIS AND DEOXYRIBONUCLEIC ACID SYNTHESIS BY PERNICIOUS ANEMIA BONE MARROW1,2

E Donnall Thomas 1, Harry L Lochte Jr 1,3
PMCID: PMC293073  PMID: 13513747

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BIRD O. D., PFIFFNER J. J. Water-soluble vitamins. I. Vitamin B12, folic acid, choline, and para-aminobenzoic acid. Annu Rev Biochem. 1956;25:397–434. doi: 10.1146/annurev.bi.25.070156.002145. [DOI] [PubMed] [Google Scholar]
  2. DOWNING M., SCHWEIGERT B. S. Rôle of vitamin B12 in nucleic acid metabolism. IV. Metabolism of C14-labeled thymidine by Lactobacillus leichmannii. J Biol Chem. 1956 Jun;220(2):521–526. [PubMed] [Google Scholar]
  3. FORD J. E., HUTNER S. H. Role of vitamin B12 in the metabolism of microorganisms. Vitam Horm. 1955;(13):101–136. doi: 10.1016/s0083-6729(08)61024-9. [DOI] [PubMed] [Google Scholar]
  4. LAJTHA L. G. Culture of human bone marrow in vitro; the reversibility between normoblastic and megaloblastic series of cells. J Clin Pathol. 1952 Feb;5(1):67–84. doi: 10.1136/jcp.5.1.67. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. LEAR A. A., HARRIS J. W., CASTLE W. B., FLEMING E. M. The serum vitamin B12 concentration in pernicious anemia. J Lab Clin Med. 1954 Nov;44(5):715–722. [PubMed] [Google Scholar]
  6. MUELLER J. F., WILL J. J. Interrelationship of folic acid, vitamin B12 and ascorbic acid in patients with megaloblastic anemia. Am J Clin Nutr. 1955 Jan-Feb;3(1):30–44. doi: 10.1093/ajcn/3.1.30. [DOI] [PubMed] [Google Scholar]
  7. NIEWEG H. O., FABER J. G., DE VRIES J. A., KROESE W. F. The relationship of vitamin B12 and folic acid in megaloblastic anemias. J Lab Clin Med. 1954 Jul;44(1):118–132. [PubMed] [Google Scholar]
  8. SWAN H. T., REISNER E. H., Jr, SILVERMAN M. The effect of various metabolites on the growth of marrow cells in vitro. Blood. 1955 Jul;10(7):735–752. [PubMed] [Google Scholar]
  9. THOMAS E. D. In vitro studies of erythropoiesis. I. The effect of normal serum on heme synthesis and oxygen consumption by bone marrow. Blood. 1955 Jun;10(6):600–611. [PubMed] [Google Scholar]
  10. THOMAS E. D., LOCHTE H. L., Jr Desoxyribonucleic acid synthesis by bone marrow cells in vitro. Blood. 1957 Dec;12(12):1086–1095. [PubMed] [Google Scholar]
  11. THOMPSON R. B. Observations on the effects of vitamin B12, liver extracts, folic acid and thymine on the maturation of megaloblasts in culture. Blood. 1952 May;7(5):522–525. [PubMed] [Google Scholar]
  12. Walsh R. J., Thomas E. D., Chow S. K., Fluharty R. G., Finch C. A. Iron Metabolism. Heme Synthesis in Vitro by Immature Erythrocytes. Science. 1949 Oct 14;110(2859):396–398. doi: 10.1126/science.110.2859.396. [DOI] [PubMed] [Google Scholar]

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